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Alexandru Ioan Cuza University

UniversityIași, Iași County, Romania

Research output, citation impact, and the most-cited recent papers from Alexandru Ioan Cuza University (Romania). Aggregated across the NobleBlocks index of 300M+ scholarly works.

Total works
23.2K
Citations
430.5K
h-index
174
i10-index
10.1K
Also known as
Alexandru Ioan Cuza UniversityUniversitatea "Alexandru Ioan Cuza"Universitatea Alexandru Ioan Cuza

Top-cited papers from Alexandru Ioan Cuza University

How Reliable are Measurement Scales? External Factors with Indirect Influence on Reliability Estimators
George Ursachi, Ioana Alexandra Horodnic, Adriana Zaiţ
2015· Procedia Economics and Finance1.4Kdoi:10.1016/s2212-5671(15)00123-9

In social economic researches we often need to measure non-observable, latent variables. For this we use special research instruments, with uni and multi dimensional scales designed for measuring the constructs of interest. Validity and reliability of these scales are crucial and special tests have been developed in this respect. Reliability concerns often arise, due to external factors that can influence the power and significance of such tests. Even for standardized instruments variations are possible, and they could seriously affect research results. The purpose of the present study is to investigate if and how external factors could influence a largely used reliability estimator - Cronbach Alpha. Several scales commonly used in marketing researches were tested, using a bootstrapping technique. Results show that important differences in the values of Cronbach Alpha are possible due to indirect influence from external factors - respondents’ age, gender, level of study, religiousness, rural/urban living, survey type and relevance of the research subject for the participants to the survey.

Grain-size effects on the ferroelectric behavior of dense nanocrystalline<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">BaTiO</mml:mi></mml:mrow><mml:mn>3</mml:mn></mml:msub></mml:mrow></mml:math>ceramics
Zhe Zhao, Vincenzo Buscaglia, Massimo Viviani, María Teresa Buscaglia +4 more
2004· Physical Review B899doi:10.1103/physrevb.70.024107

A progressive reduction of tetragonal distortion, heat of transition, Curie temperature, and relative dielectric constant has been observed on dense ${\mathrm{BaTiO}}_{3}$ ceramics with grain size decreasing from 1200 to $50\phantom{\rule{0.3em}{0ex}}\mathrm{nm}$. The correlations between grain size, extent of tetragonal distortion, and ferroelectric properties strongly support the existence of an intrinsic size effect. From the experimental trends the critical size for disappearance of ferroelectricity has been evaluated to be $10--30\phantom{\rule{0.3em}{0ex}}\mathrm{nm}$. The strong depression of the relative permittivity observed for the nanocrystalline ceramics can be ascribed to the combination of the intrinsic size effect and of the size-dependent ``dilution'' effect of a grain boundary ``dead'' layer.

Entrepreneurship Education through Successful Entrepreneurial Models in Higher Education Institutions
Gabriela Boldureanu, Alina Măriuca Ionescu, Ana‐Maria Bercu, Maria Viorica Bedrule-Grigoruță +1 more
2020· Sustainability621doi:10.3390/su12031267

In higher education institutions, entrepreneurship learning based on successful entrepreneurial role models may promote education for sustainable development. Several theoretical perspectives, such as the human capital theory, the entrepreneurial self-efficacy and self-determination theory, argue that entrepreneurship education is positively correlated with entrepreneurial intentions of students, as it provides adequate know-how and skills and motivates them to develop their entrepreneurial careers. In entrepreneurship education programmes, exposure to successful entrepreneurial models could be a significant factor for stimulating students’ confidence in their ability to start a business and for improving their attitudes towards entrepreneurship. This study aims (i) to identify characteristics viewed by students as being specific to a successful entrepreneur, (ii) to establish the influence of exposure to successful entrepreneurial role models (chosen by students) during entrepreneurship education classes on student entrepreneurial intentions, and (iii) to assess how such exposure influences the attitudes of students towards entrepreneurship. For this purpose, the authors ran a pilot experiment with 30 graduate students enrolled in a Business Creation course using a research methodology that combined qualitative techniques with quantitative measures. Content and statistical analyses were utilised to examine differences in student entrepreneurial intentions and attitudes towards entrepreneurship after being exposed to successful entrepreneurial models. Our study provides evidence that entrepreneurship education based on successful entrepreneurial role models may positively influence the entrepreneurial attitudes and intentions of students and could lead to higher orientation of student perception towards social benefits of entrepreneurship (new jobs) compared to financial ones (high income). However, our findings stress that if educators want to improve the efficiency of education focused on developing entrepreneurial skills, graduate programmes should be designed differently for business and non-business students, since studying successful entrepreneurial stories impacts these two groups differently.

Electron and photon performance measurements with the ATLAS detector using the 2015–2017 LHC proton-proton collision data
G. Aad, B. Abbott, D. C. Abbott, A. Abed Abud +4 more
2019· Journal of Instrumentation530doi:10.1088/1748-0221/14/12/p12006

: This paper describes the reconstruction of electrons and photons with the ATLAS detector, employed for measurements and searches exploiting the complete LHC Run 2 dataset. An improved energy clustering algorithm is introduced, and its implications for the measurement and identification of prompt electrons and photons are discussed in detail. Corrections and calibrations that affect performance, including energy calibration, identification and isolation efficiencies, and the measurement of the charge of reconstructed electron candidates are determined using up to 81 fb -1 of proton-proton collision data collected at s = 13 TeV between 2015 and 2017.

Climate anxiety, wellbeing and pro-environmental action: correlates of negative emotional responses to climate change in 32 countries
Charles A. Ogunbode, Rouven Doran, Daniel Hanss, Maria Ojala +4 more
2022· Journal of Environmental Psychology529doi:10.1016/j.jenvp.2022.101887

This study explored the correlates of climate anxiety in a diverse range of national contexts. We analysed cross-sectional data gathered in 32 countries (N = 12,246). Our results show that climate anxiety is positively related to rate of exposure to information about climate change impacts, the amount of attention people pay to climate change information, and perceived descriptive norms about emotional responding to climate change. Climate anxiety was also positively linked to pro-environmental behaviours and negatively linked to mental wellbeing. Notably, climate anxiety had a significant inverse association with mental wellbeing in 31 out of 32 countries. In contrast, it had a significant association with pro-environmental behaviour in 24 countries, and with environmental activism in 12 countries. Our findings highlight contextual boundaries to engagement in environmental action as an antidote to climate anxiety, and the broad international significance of considering negative climate-related emotions as a plausible threat to wellbeing.

Combined measurements of Higgs boson production and decay using up to <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mn>80</mml:mn><mml:mtext> </mml:mtext><mml:mtext> </mml:mtext><mml:msup><mml:mrow><mml:mi>fb</mml:mi></mml:mrow><mml:mrow><mml:mo>−</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math> of proton-proton collision data at <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msqrt><mml:mi>s</mml:mi></mml:msqrt><mml:mo>=</mml:mo><mml:mn>13</mml:mn><mml:mtext> </mml:mtext><mml:mtext> </mml:mtext><mml:mi>TeV</mml:mi></mml:math> collected with the ATLAS experiment
G. Aad, B. Abbott, D. C. Abbott, O. Abdinov +4 more
2020· Physical review. D/Physical review. D.495doi:10.1103/physrevd.101.012002

Combined measurements of Higgs boson production cross sections and branching fractions are presented. The combination is based on the analyses of the Higgs boson decay modes $H\ensuremath{\rightarrow}\ensuremath{\gamma}\ensuremath{\gamma}$, $Z{Z}^{*}$, $W{W}^{*}$, $\ensuremath{\tau}\ensuremath{\tau}$, $b\overline{b}$, $\ensuremath{\mu}\ensuremath{\mu}$, searches for decays into invisible final states, and on measurements of off-shell Higgs boson production. Up to $79.8\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of proton--proton collision data collected at $\sqrt{s}=13\text{ }\text{ }\mathrm{TeV}$ with the ATLAS detector are used. Results are presented for the gluon--gluon fusion and vector-boson fusion processes, and for associated production with vector bosons or top-quarks. The global signal strength is determined to be $\ensuremath{\mu}=1.1{1}_{\ensuremath{-}0.08}^{+0.09}$. The combined measurement yields an observed (expected) significance for the vector-boson fusion production process of $6.5\ensuremath{\sigma}$ ($5.3\ensuremath{\sigma}$). Measurements in kinematic regions defined within the simplified template cross section framework are also shown. The results are interpreted in terms of modifiers applied to the Standard Model couplings of the Higgs boson to other particles, and are used to set exclusion limits on parameters in two-Higgs-doublet models and in the simplified minimal supersymmetric Standard Model. No significant deviations from Standard Model predictions are observed.

Determinants of Banks’ Profitability: Evidence from EU 27 Banking Systems
Nicolae Petria, Bogdan Căpraru, Iulian Ihnatov
2015· Procedia Economics and Finance472doi:10.1016/s2212-5671(15)00104-5

In this study we assess the main determinants of banks’ profitability in EU27 over the period 2004-2011. We split the factors that influence bank profitability in two large groups: bank-specific (internal) factors and industry specific and macroeconomic (external) factors. We consider as proxy for banks profitability the return on average assets (ROAA) and the return on average equity (ROAE). The empirical findings are consistent with the expected results. Credit and liquidity risk, management efficiency, the diversification of business, the market concentration/competition and the economic growth have influence on bank profitability, both on ROAA and ROAE. An interesting and valuable result is the positive influence of competition on bank profitability in EU27.

EUNIS Habitat Classification: Expert system, characteristic species combinations and distribution maps of European habitats
Milan Chytrý, Lubomír Tichý, S.M. Hennekens, Ilona Knollová +4 more
2020· Applied Vegetation Science440doi:10.1111/avsc.12519

Abstract Aim The EUNIS Habitat Classification is a widely used reference framework for European habitat types (habitats), but it lacks formal definitions of individual habitats that would enable their unequivocal identification. Our goal was to develop a tool for assigning vegetation‐plot records to the habitats of the EUNIS system, use it to classify a European vegetation‐plot database, and compile statistically‐derived characteristic species combinations and distribution maps for these habitats. Location Europe. Methods We developed the classification expert system EUNIS‐ESy, which contains definitions of individual EUNIS habitats based on their species composition and geographic location. Each habitat was formally defined as a formula in a computer language combining algebraic and set‐theoretic concepts with formal logical operators. We applied this expert system to classify 1,261,373 vegetation plots from the European Vegetation Archive (EVA) and other databases. Then we determined diagnostic, constant and dominant species for each habitat by calculating species‐to‐habitat fidelity and constancy (occurrence frequency) in the classified data set. Finally, we mapped the plot locations for each habitat. Results Formal definitions were developed for 199 habitats at Level 3 of the EUNIS hierarchy, including 25 coastal, 18 wetland, 55 grassland, 43 shrubland, 46 forest and 12 man‐made habitats. The expert system classified 1,125,121 vegetation plots to these habitat groups and 73,188 to other habitats, while 63,064 plots remained unclassified or were classified to more than one habitat. Data on each habitat were summarized in factsheets containing habitat description, distribution map, corresponding syntaxa and characteristic species combination. Conclusions EUNIS habitats were characterized for the first time in terms of their species composition and distribution, based on a classification of a European database of vegetation plots using the newly developed electronic expert system EUNIS‐ESy. The data provided and the expert system have considerable potential for future use in European nature conservation planning, monitoring and assessment.

ATLAS b-jet identification performance and efficiency measurement with $$t{\bar{t}}$$ events in pp collisions at $$\sqrt{s}=13$$ TeV
G. Aad, B. Abbott, D. C. Abbott, A. Abed Abud +4 more
2019· The European Physical Journal C437doi:10.1140/epjc/s10052-019-7450-8

Abstract The algorithms used by the ATLAS Collaboration during Run 2 of the Large Hadron Collider to identify jets containing b -hadrons are presented. The performance of the algorithms is evaluated in the simulation and the efficiency with which these algorithms identify jets containing b -hadrons is measured in collision data. The measurement uses a likelihood-based method in a sample highly enriched in $$t{\bar{t}}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>t</mml:mi><mml:mover><mml:mrow><mml:mi>t</mml:mi></mml:mrow><mml:mrow><mml:mo>¯</mml:mo></mml:mrow></mml:mover></mml:mrow></mml:math> events. The topology of the $$t \rightarrow W b$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>t</mml:mi><mml:mo>→</mml:mo><mml:mi>W</mml:mi><mml:mi>b</mml:mi></mml:mrow></mml:math> decays is exploited to simultaneously measure both the jet flavour composition of the sample and the efficiency in a transverse momentum range from 20 to 600 GeV. The efficiency measurement is subsequently compared with that predicted by the simulation. The data used in this measurement, corresponding to a total integrated luminosity of 80.5 $$\hbox {fb}^{-1}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msup><mml:mtext>fb</mml:mtext><mml:mrow><mml:mo>-</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msup></mml:math> , were collected in proton–proton collisions during the years 2015–2017 at a centre-of-mass energy $$\sqrt{s}=$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msqrt><mml:mi>s</mml:mi></mml:msqrt><mml:mo>=</mml:mo></mml:mrow></mml:math> 13 TeV. By simultaneously extracting both the efficiency and jet flavour composition, this measurement significantly improves the precision compared to previous results, with uncertainties ranging from 1 to 8% depending on the jet transverse momentum.

Differential equations driven by fractional Brownian motion
David Nualart, Aurel Răşcanu
2002· Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)434

A global existence and uniqueness result of the solution for multidimensional, time dependent, stochastic differential equations driven by a fractional Brownian motion with Hurst parameter H> is proved. It is shown, also, that the solution has finite moments. The result is based on a deterministic existence and uniqueness theorem whose proof uses a contraction principle and a priori estimates.

Study of the material of the ATLAS inner detector for Run 2 of the LHC
M. Aaboud, G. Aad, B. Abbott, J. Abdallah +4 more
2017· Journal of Instrumentation431doi:10.1088/1748-0221/12/12/p12009

The ATLAS inner detector comprises three different sub-detectors: the pixel detector, the silicon strip tracker, and the transition-radiation drift-tube tracker. The Insertable $B$-Layer, a new innermost pixel layer, was installed during the shutdown period in 2014, together with modifications to the layout of the cables and support structures of the existing pixel detector. The material in the inner detector is studied with several methods, using a low-luminosity $\sqrt{s}=13$ TeV $pp$ collision sample corresponding to around $2.0\,\mathrm{nb}^{-1}$ collected in 2015 with the ATLAS experiment at the LHC. In this paper, the material within the innermost barrel region is studied using reconstructed hadronic interaction and photon conversion vertices. For the forward rapidity region, the material is probed by a measurement of the efficiency with which single tracks reconstructed from pixel detector hits alone can be extended with hits on the track in the strip layers. The results of these studies have been taken into account in an improved description of the material in the ATLAS inner detector simulation, resulting in a reduction in the uncertainties associated with the charged-particle reconstruction efficiency determined from simulation.

Jet reconstruction and performance using particle flow with the ATLAS Detector
M. Aaboud, G. Aad, B. Abbott, J. Abdallah +4 more
2017· The European Physical Journal C425doi:10.1140/epjc/s10052-017-5031-2

This paper describes the implementation and performance of a particle flow algorithm applied to 20.2 fb[Formula: see text] of ATLAS data from 8 TeV proton-proton collisions in Run 1 of the LHC. The algorithm removes calorimeter energy deposits due to charged hadrons from consideration during jet reconstruction, instead using measurements of their momenta from the inner tracker. This improves the accuracy of the charged-hadron measurement, while retaining the calorimeter measurements of neutral-particle energies. The paper places emphasis on how this is achieved, while minimising double-counting of charged-hadron signals between the inner tracker and calorimeter. The performance of particle flow jets, formed from the ensemble of signals from the calorimeter and the inner tracker, is compared to that of jets reconstructed from calorimeter energy deposits alone, demonstrating improvements in resolution and pile-up stability.

Advantages and Challenges of Adopting Cloud Computing from an Enterprise Perspective
Mihai Avram
2014· Procedia Technology414doi:10.1016/j.protcy.2013.12.525

With the rapid development of processing and storage technologies and the success of the Internet, computing resources have become cheaper, more powerful and more available than ever before. This technological trend has enabled the realization of a new computing model called cloud computing, in which resources are provided as general utilities that can be leased and released by users through the Internet in an on-demand fashion. The organizations are gaining more experience in the cloud and they start to shift more core business functions onto cloud platforms. Because of this fact, we are seeing that cloud adoption is significantly more complex than we imagined initially, particularly in terms of data management, system integration and the management of multiple cloud providers. Cloud computing is of growing interest to companies around the globe, but many are finding greater costs and greater obstacles to the adoption of cloud computing than they anticipated. In this case, is cloud computing still able to deliver all the promises? In this paper we will analyze from a company's point of view the factors that need to be considered by an enterprise when making the decision of using cloud computing. Some of the companies are moving towards cloud computing just because it is the latest trend in information technology. On the other hand, other companies cannot even take into consideration the idea of having their sensitive data outside their premises. Both of these cases represent companies that are just not very well informed. We are not sustaining that cloud computing is a perfect solution for everybody, but adopting it or not should be result of a very well informed analysis. We will analyze the positive and negative aspects of each of the following factors: integration with existing IT infrastructure and existing software, costs, return on investment, performances, security. Also, we will correlate all these factors with the company size and business area in order to identify if or what type of cloud computing solution is suitable for their needs.

A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery
G. Aad, B. Abbott, D. C. Abbott, K. Abeling +4 more
2022· Nature412doi:10.1038/s41586-022-04893-w

Abstract The standard model of particle physics 1–4 describes the known fundamental particles and forces that make up our Universe, with the exception of gravity. One of the central features of the standard model is a field that permeates all of space and interacts with fundamental particles 5–9 . The quantum excitation of this field, known as the Higgs field, manifests itself as the Higgs boson, the only fundamental particle with no spin. In 2012, a particle with properties consistent with the Higgs boson of the standard model was observed by the ATLAS and CMS experiments at the Large Hadron Collider at CERN 10,11 . Since then, more than 30 times as many Higgs bosons have been recorded by the ATLAS experiment, enabling much more precise measurements and new tests of the theory. Here, on the basis of this larger dataset, we combine an unprecedented number of production and decay processes of the Higgs boson to scrutinize its interactions with elementary particles. Interactions with gluons, photons, and W and Z bosons—the carriers of the strong, electromagnetic and weak forces—are studied in detail. Interactions with three third-generation matter particles (bottom ( b ) and top ( t ) quarks, and tau leptons ( τ )) are well measured and indications of interactions with a second-generation particle (muons, μ ) are emerging. These tests reveal that the Higgs boson discovered ten years ago is remarkably consistent with the predictions of the theory and provide stringent constraints on many models of new phenomena beyond the standard model.

Performance of electron and photon triggers in ATLAS during LHC Run 2
G. Aad, B. Abbott, D. C. Abbott, A. Abed Abud +4 more
2020· The European Physical Journal C407doi:10.1140/epjc/s10052-019-7500-2

Abstract Electron and photon triggers covering transverse energies from 5 $$\text {GeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>GeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> to several $$\text {TeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>TeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> are essential for the ATLAS experiment to record signals for a wide variety of physics: from Standard Model processes to searches for new phenomena in both proton–proton and heavy-ion collisions. To cope with a fourfold increase of peak LHC luminosity from 2015 to 2018 (Run 2), to $$2.1 \times 10^{34}\,\hbox {cm}^{-2}\hbox { s}^{-1}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mn>2.1</mml:mn><mml:mo>×</mml:mo><mml:msup><mml:mn>10</mml:mn><mml:mn>34</mml:mn></mml:msup><mml:mspace/><mml:msup><mml:mtext>cm</mml:mtext><mml:mrow><mml:mo>-</mml:mo><mml:mn>2</mml:mn></mml:mrow></mml:msup><mml:mspace/><mml:msup><mml:mtext>s</mml:mtext><mml:mrow><mml:mo>-</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math> , and a similar increase in the number of interactions per beam-crossing to about 60, trigger algorithms and selections were optimised to control the rates while retaining a high efficiency for physics analyses. For proton–proton collisions, the single-electron trigger efficiency relative to a single-electron offline selection is at least 75% for an offline electron of 31 $$\text {GeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>GeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> , and rises to 96% at 60 $$\text {GeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>GeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> ; the trigger efficiency of a 25 $$\text {GeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>GeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> leg of the primary diphoton trigger relative to a tight offline photon selection is more than 96% for an offline photon of 30 $$\text {GeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>GeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> . For heavy-ion collisions, the primary electron and photon trigger efficiencies relative to the corresponding standard offline selections are at least 84% and 95%, respectively, at 5 $$\text {GeV }$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mtext>GeV</mml:mtext><mml:mspace/></mml:mrow></mml:math> above the corresponding trigger threshold.

Evidence for light-by-light scattering in heavy-ion collisions with the ATLAS detector at the LHC
P. Jackson, L. Lee, A. Petridis, M. J. White +4 more
2017· Nature Physics394doi:10.1038/nphys4208

Light-by-light scattering (γγ → γγ) is a quantum-mechanical process that is forbidden in the classical theory of electrodynamics. This reaction is accessible at the Large Hadron Collider thanks to the large electromagnetic field strengths generated by ultra-relativistic colliding lead ions. Using 480 μb−1 of lead–lead collision data recorded at a centre-of-mass energy per nucleon pair of 5.02 TeV by the ATLAS detector, here we report evidence for light-by-light scattering. A total of 13 candidate events were observed with an expected background of 2.6 ± 0.7 events. After background subtraction and analysis corrections, the fiducial cross-section of the process Pb + Pb (γγ) → Pb(∗) + Pb(∗)γγ, for photon transverse energy ET > 3 GeV, photon absolute pseudorapidity |η| < 2.4, diphoton invariant mass greater than 6 GeV, diphoton transverse momentum lower than 2 GeV and diphoton acoplanarity below 0.01, is measured to be 70 ± 24 (stat.) ± 17 (syst.) nb, which is in agreement with the standard model predictions. Quantum electrodynamics predicts a rare process in which light is scattered by light. The ATLAS Collaboration reports signs of this elusive effect in the collisions of ultra-relativistic lead ions.

Future Antimicrobials: Natural and Functionalized Phenolics
Andrei Lobiuc, Naomi-Eunicia Pavăl, Ionel I. Mangalagiu, Roxana Gheorghiță +3 more
2023· Molecules392doi:10.3390/molecules28031114

With incidence of antimicrobial resistance rising globally, there is a continuous need for development of new antimicrobial molecules. Phenolic compounds having a versatile scaffold that allows for a broad range of chemical additions; they also exhibit potent antimicrobial activities which can be enhanced significantly through functionalization. Synthetic routes such as esterification, phosphorylation, hydroxylation or enzymatic conjugation may increase the antimicrobial activity of compounds and reduce minimal concentrations needed. With potent action mechanisms interfering with bacterial cell wall synthesis, DNA replication or enzyme production, phenolics can target multiple sites in bacteria, leading to a much higher sensitivity of cells towards these natural compounds. The current review summarizes some of the most important knowledge on functionalization of natural phenolic compounds and the effects on their antimicrobial activity.

Muon reconstruction and identification efficiency in ATLAS using the full Run 2 pp collision data set at $$\sqrt{s}=13$$ TeV
G. Aad, B. Abbott, D. C. Abbott, A. Abed Abud +4 more
2021· The European Physical Journal C378doi:10.1140/epjc/s10052-021-09233-2

Abstract This article documents the muon reconstruction and identification efficiency obtained by the ATLAS experiment for 139 $$\hbox {fb}^{-1}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msup><mml:mtext>fb</mml:mtext><mml:mrow><mml:mo>-</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msup></mml:math> of pp collision data at $$\sqrt{s}=13$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msqrt><mml:mi>s</mml:mi></mml:msqrt><mml:mo>=</mml:mo><mml:mn>13</mml:mn></mml:mrow></mml:math> TeV collected between 2015 and 2018 during Run 2 of the LHC. The increased instantaneous luminosity delivered by the LHC over this period required a reoptimisation of the criteria for the identification of prompt muons. Improved and newly developed algorithms were deployed to preserve high muon identification efficiency with a low misidentification rate and good momentum resolution. The availability of large samples of $$Z\rightarrow \mu \mu $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>Z</mml:mi><mml:mo>→</mml:mo><mml:mi>μ</mml:mi><mml:mi>μ</mml:mi></mml:mrow></mml:math> and $$J/\psi \rightarrow \mu \mu $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>J</mml:mi><mml:mo>/</mml:mo><mml:mi>ψ</mml:mi><mml:mo>→</mml:mo><mml:mi>μ</mml:mi><mml:mi>μ</mml:mi></mml:mrow></mml:math> decays, and the minimisation of systematic uncertainties, allows the efficiencies of criteria for muon identification, primary vertex association, and isolation to be measured with an accuracy at the per-mille level in the bulk of the phase space, and up to the percent level in complex kinematic configurations. Excellent performance is achieved over a range of transverse momenta from 3 GeV to several hundred GeV, and across the full muon detector acceptance of $$|\eta |&lt;2.7$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mo>|</mml:mo><mml:mi>η</mml:mi><mml:mo>|</mml:mo><mml:mo>&lt;</mml:mo><mml:mn>2.7</mml:mn></mml:mrow></mml:math> .

Performance of missing transverse momentum reconstruction with the ATLAS detector using proton–proton collisions at $$\sqrt{s}=13~\hbox {TeV}$$ s = 13 TeV
M. Aaboud, G. Aad, B. Abbott, O. Abdinov +4 more
2018· The European Physical Journal C375doi:10.1140/epjc/s10052-018-6288-9

The performance of the missing transverse momentum (E miss T ) reconstruction with the ATLAS detector is evaluated using data collected in proton-proton collisions at the LHC at a centre-of-mass energy of 13 TeV in 2015.

A Critical Review of Bottom-Up Proteomics: The Good, the Bad, and the Future of This Field
Emmalyn J. Dupree, Madhuri Jayathirtha, Hannah Yorkey, Marius Mihăşan +2 more
2020· Proteomes362doi:10.3390/proteomes8030014

Proteomics is the field of study that includes the analysis of proteins, from either a basic science prospective or a clinical one. Proteins can be investigated for their abundance, variety of proteoforms due to post-translational modifications (PTMs), and their stable or transient protein-protein interactions. This can be especially beneficial in the clinical setting when studying proteins involved in different diseases and conditions. Here, we aim to describe a bottom-up proteomics workflow from sample preparation to data analysis, including all of its benefits and pitfalls. We also describe potential improvements in this type of proteomics workflow for the future.