NobleBlocks

China Railway Group (China)

companyBeijing, China

Research output, citation impact, and the most-cited recent papers from China Railway Group (China) (China). Aggregated across the NobleBlocks index of 300M+ scholarly works.

Total works
9.5K
Citations
68.9K
h-index
82
i10-index
2.0K
Also known as
China Railway Group (China)中國中鐵股份有限公司

Top-cited papers from China Railway Group (China)

Effect of Remote Ischemic Conditioning vs Usual Care on Neurologic Function in Patients With Acute Moderate Ischemic Stroke
Dawei Chen, Yu Cui, Xiaoqiu Li, Xinhong Wang +4 more
2022· JAMA175doi:10.1001/jama.2022.13123

Importance: Preclinical and clinical studies have suggested a neuroprotective effect of remote ischemic conditioning (RIC), which involves repeated occlusion/release cycles on bilateral upper limb arteries; however, robust evidence in patients with ischemic stroke is lacking. Objective: To assess the efficacy of RIC for acute moderate ischemic stroke. Design, Setting, and Participants: This multicenter, open-label, blinded-end point, randomized clinical trial including 1893 patients with acute moderate ischemic stroke was conducted at 55 hospitals in China from December 26, 2018, through January 19, 2021, and the date of final follow-up was April 19, 2021. Interventions: Eligible patients were randomly assigned within 48 hours after symptom onset to receive treatment with RIC (using a pneumatic electronic device and consisting of 5 cycles of cuff inflation for 5 minutes and deflation for 5 minutes to the bilateral upper limbs to 200 mm Hg) for 10 to 14 days as an adjunct to guideline-based treatment (n = 922) or guideline-based treatment alone (n = 971). Main Outcomes and Measures: The primary end point was excellent functional outcome at 90 days, defined as a modified Rankin Scale score of 0 to 1. All end points had blinded assessment and were analyzed on a full analysis set. Results: Among 1893 eligible patients with acute moderate ischemic stroke who were randomized (mean [SD] age, 65 [10.3] years; 606 women [34.1%]), 1776 (93.8%) completed the trial. The number with excellent functional outcome at 90 days was 582 (67.4%) in the RIC group and 566 (62.0%) in the control group (risk difference, 5.4% [95% CI, 1.0%-9.9%]; odds ratio, 1.27 [95% CI, 1.05-1.54]; P = .02). The proportion of patients with any adverse events was 6.8% (59/863) in the RIC group and 5.6% (51/913) in the control group. Conclusions and Relevance: Among adults with acute moderate ischemic stroke, treatment with remote ischemic conditioning compared with usual care significantly increased the likelihood of excellent neurologic function at 90 days. However, these findings require replication in another trial before concluding efficacy for this intervention. Trial Registration: ClinicalTrials.gov Identifier: NCT03740971.

Overview of Harmonic and Resonance in Railway Electrification Systems
Haitao Hu, Yang Shao, Li Tang, Jin Ma +2 more
2018· IEEE Transactions on Industry Applications164doi:10.1109/tia.2018.2813967

Harmonic distortion and harmonic resonance problems have been widely concerned and reported in railway electrification systems (RESs) due to the harmonic injection from the nonlinear electric train, especially high-speed/high-capacity/large-power trains. This paper presents an overview of the harmonic and resonance problems in the RES, including harmonic problem composition, harmonic modeling, available influential factors assessment, harmonic resonance, and associated suppression methods. The harmonic problem mainly consists of the background harmonics brought from the utility system, resonance-region harmonics interacted by capacitive and inductive network elements, and characteristic harmonics generated from the switching process of the onboard power conversion system. The mathematical modeling and analysis methods are introduced, including frequency scanning analysis, S-domain analysis, resonance mode analysis, and modal sensitivity analysis. Available influential factors/parameters have been fully investigated against above-mentioned harmonic problems. Finally, different harmonic suppression methods have been compared and summarized in this paper.

Zoned Excavation of an Oversized Pit Close to an Existing Metro Line in Stiff Clay: Case Study
Yong Tan, Xiang Li, Zhijun Kang, Junxi Liu +1 more
2014· Journal of Performance of Constructed Facilities155doi:10.1061/(asce)cf.1943-5509.0000652

Because greenfields available for new developments in congested urban areas are scarce in China, more and more excavations for building basements or other underground facilities (e.g., new metro lines, underground shopping malls, parking garages) have to be carried out in the close proximity of existing metro lines. To ensure project safety, it is essential to know potential adverse effects of excavations on adjacent metro lines in service. Until now, many studies have contributed to the cases of excavations overlying existing tunnels. In contrast, only a few were known for excavations parallel to adjacent existing tunnels. With regard to the responses of existing metro stations to adjacent excavations, few case studies were reported in the literature. Through an extensive field instrumentation program in combination of numerical simulations, this study examines the performance of an oversized deep excavation in stiff clayey deposits and the corresponding responses of the adjacent metro station and twin shield tunnels in service. Taking advantage of the adopted zoned-construction procedure, both wall deflections and ground settlements of this oversized pit were not as significant as those reported in the literature, even smaller than those of long and narrow metro station pits. Consequently, both deformations and displacements of the existing metro line were within acceptable limits, and no obvious structural damage was observed. Throughout the excavation, the two-level island-type metro station exhibited a good structural integrity, which settled uniformly along the transverse direction and tilted slightly along the longitudinal direction. As to the twin shield tunnel linings, the one located within the primary ground influence zone developed considerably larger settlements and deformations than the other one within the secondary influence zone. As a product of the lateral stress relief attributable to soil removal, the tunnel lining experienced apparent elongations in the horizontal direction.

A Comprehensive Operation and Revenue Analysis Algorithm for LTE/5G Wireless System Based on Telecom Operator Data
Lexi Xu, Xueqing Zhao, Yanli Yu, Yuting Luan +4 more
2019137doi:10.1109/smartworld-uic-atc-scalcom-iop-sci.2019.00274

The operation condition of wireless system directly impacts both the system performance and the quality of experience (QoE). On the basis of telecom operator data, this paper designs a comprehensive operation and revenue analysis (CORA) algorithm for LTE/5G wireless system. The objective of the proposed CORA algorithm is to analyze and evaluate both the operation state and the revenue of base station (BS) in the wireless system. The designed CORA algorithm is applied in the realistic 4G wireless system. The CORA algorithm can assist telecom operator to effectively analyze and evaluate the BS comprehensive state of operation and revenue.

Review of PPP–RTK: achievements, challenges, and opportunities
Xingxing Li, Jiaxin Huang, Xin Li, Zhiheng Shen +3 more
2022· Satellite Navigation127doi:10.1186/s43020-022-00089-9

Abstract The PPP–RTK method, which combines the concepts of Precise of Point Positioning (PPP) and Real-Time Kinematic (RTK), is proposed to provide a centimeter-accuracy positioning service for an unlimited number of users. Recently, the PPP–RTK technique is becoming a promising tool for emerging applications such as autonomous vehicles and unmanned logistics as it has several advantages including high precision, full flexibility, and good privacy. This paper gives a detailed review of PPP–RTK focusing on its implementation methods, recent achievements as well as challenges and opportunities. Firstly, the fundamental approach to implement PPP–RTK is described and an overview of the research on key techniques, such as Uncalibrated Phase Delay (UPD) estimation, precise atmospheric correction retrieval and modeling, and fast PPP ambiguity resolution, is given. Then, the recent efforts and progress are addressed, such as improving the performance of PPP–RTK by combining multi-GNSS and multi-frequency observations, single-frequency PPP–RTK for low-cost devices, and PPP–RTK for vehicle navigation. Also, the system construction and applications based on the PPP–RTK method are summarized. Moreover, the main issues that impact PPP–RTK performance are highlighted, including signal occlusion in complex urban areas and atmosphere modeling in extreme weather events. The new opportunities brought by the rapid development of low-cost markets, multiple sensors, and new-generation Low Earth Orbit (LEO) navigation constellation are also discussed. Finally, the paper concludes with some comments and the prospects for future research.

When do emotionally exhausted employees speak up? Exploring the potential curvilinear relationship between emotional exhaustion and voice
Xin Qin, Marco S. DiRenzo, Minya Xu, Yilong Duan
2014· Journal of Organizational Behavior115doi:10.1002/job.1948

Summary Two studies were conducted to address the potential nonlinear relationship between emotional exhaustion and voice. Study 1 developed and tested a model rooted in conservation of resources theory in which responses to emotional exhaustion are determined by individual‐level and group‐level conditions that influence the perceived safety and efficacy of voice and drive prohibitive voice behaviors by giving rise to either resource‐conservation‐based or resource‐acquisition‐based motivation. Specifically, there was a curvilinear (U‐shaped) relationship between emotional exhaustion and prohibitive voice under conditions of (i) high job security and (ii) high interactional justice climate, but a linearly negative relationship when these resources were low. Study 2 replicated and extended these findings to include an empirical examination of these effects on promotive versus prohibitive voice. Results confirmed the findings of Study 1, provided evidence of differences in the nomological networks of promotive and prohibitive voice, and indicated that prohibitive voice is more salient to the experience of high emotional strain. Implications of the findings and areas for future research are discussed. Copyright © 2014 John Wiley & Sons, Ltd.

Cyclic constitutive equations of rock with coupled damage induced by compaction and cracking
Chonghong Ren, Jin Yu, Xueying Liu, Zhuqing Zhang +1 more
2022· International Journal of Mining Science and Technology104doi:10.1016/j.ijmst.2022.06.010

In this paper, the cyclic constitutive equations were proposed to describe the constitutive behavior of cyclic loading and unloading. Firstly, a coupled damage variable was derived, which contains two parts, i.e., the compaction-induced damage and the cracking-induced damage. The compaction-induced damage variable was derived from a nonlinear stress–strain relation of the initial compaction stage, and the cracking-induced damage variable was established based on the statistical damage theory. Secondly, based on the total damage variable, a damage constitutive equation was proposed to describe the constitutive relation of rock under the monotonic uniaxial compression conditions, whereafter, the application of this model is extended to cyclic loading and unloading conditions. To validate the proposed monotonic and cyclic constitutive equations, a series of mechanical tests for marble specimens were carried out, which contained the monotonic uniaxial compression (MUC) experiment, cyclic uniaxial compression experiments under the variable amplitude (CUC-VA) and constant amplitude (CUC-CA) conditions. The results show that the proposed total damage variable comprehensively reflects the damage evolution characteristic, i.e., the damage variable firstly decreases, then increases no matter under the conditions of MUC, CUC-VA or CUC-CA. Then a reasonable consistency is observed between the experimental and theoretical curves. The proposed cyclic constitutive equations can simulate the whole cyclic loading and unloading behaviors, such as the initial compaction, the strain hardening and the strain softening. Furthermore, the shapes of the theoretical curves are controlled by the modified coefficient, compaction sensitivity coefficient and two Weibull distributed parameters.

Lessons Learned from Construction of Shanghai Metro Stations: Importance of Quick Excavation, Prompt Propping, Timely Casting, and Segmented Construction
Yong Tan, Bin Wei, Xin Zhou, Yanping Diao
2014· Journal of Performance of Constructed Facilities102doi:10.1061/(asce)cf.1943-5509.0000599

Four metro stations with similar supporting systems and pit geometries in Shanghai soft clay were excavated using different soil removal procedures, which led to distinctly different pit behaviors. Through analyzing and comparing the well-documented field data from these four bottom-up excavations, the significances of quick excavation, promptly propping, timely casting of floor slabs, and segmented construction in control of pit deformations were identified and their influences were comprehensively quantified. As to these four pits, the measured time-dependent wall deflections and wall heaves in 20–35 days at relatively deep excavation levels were up to 47–94% the magnitudes at completion of excavation to the final depths. The measured postexcavation wall deflections in about 20–30 days were up to 36–45% the maximum wall deflections at completion of excavation and the corresponding postexcavation deflection rates were up to twice those during excavation. The poorly excavated pits, which featured long excavation duration, long wall exposure lengths, or delay in propping struts or casting floor slabs, experienced wall deflections and ground settlements 1–4 times greater than the appropriately excavated pit. The wall deflection rates of the poorly excavated pits were up to 2–3× and 4–6× those of the appropriately excavated pit during and after excavation, respectively. Compared with the countermeasure of increasing supporting system stiffness by casting rigid concrete struts and/or bracing double steel pipe struts at one level, the approach of quick excavation, promptly propping, and timely casting of rigid floor slabs in combination with a segmented construction procedure was demonstrated to be much more efficient in controlling excavation-induced deformations.

Degradation of concrete in marine environment under coupled chloride and sulfate attack: A numerical and experimental study
Dandan Sun, Zhenjie Cao, Changfu Huang, Kai Wu +2 more
2022· Case Studies in Construction Materials95doi:10.1016/j.cscm.2022.e01218

The corrosion of offshore reinforced concrete structures under combined chloride and sulfate ions attack is a complex corrosion phenomenon. The purpose of this study is to develop numerical models in conjunction with experimental studies for long-term durability assessment of offshore concrete structures. A numerical model was developed to describe the simultaneously transport of chloride and sulfate ions considering the competitive binding by hardened cement pastes effect. The model was validated by a series of experimental studies. The validated model was implemented to predict the service life of the offshore RC structures under various chloride and sulfate solutions. The results show that chloride ions induced corrosion of steel bars in offshore RC structures is highly influenced by the concentration of sulfate ions. The sulfate ions induced concrete expansion and cracking from ettringite formation could potentially accelerate chloride ions induced corrosion of steel bars in concrete, ultimately the premature failure of the offshore RC structures.

Iron-Based Shape Memory Alloys in Construction: Research, Applications and Opportunities
Zhe-Xi Zhang, Jie Zhang, Honglei Wu, Yuezhen Ji +1 more
2022· Materials94doi:10.3390/ma15051723

As a promising candidate in the construction industry, iron-based shape memory alloy (Fe-SMA) has attracted lots of attention in the engineering and metallography communities because of its foreseeable benefits including corrosion resistance, shape recovery capability, excellent plastic deformability, and outstanding fatigue resistance. Pilot applications have proved the feasibility of Fe-SMA as a highly efficient functional material in the construction sector. This paper provides a review of recent developments in research and design practice related to Fe-SMA. The basic mechanical properties are presented and compared with conventional structural steel, and some necessary explanations are given on the metallographic transformation mechanism. Newly emerged applications, such as Fe-SMA-based prestressing/strengthening techniques and seismic-resistant components/devices, are discussed. It is believed that Fe-SMA offers a wide range of applications in the construction industry but there still remains problems to be addressed and areas to be further explored. Some research needs at material-level, component-level, and system-level are highlighted in this paper. With the systematic information provided, this paper not only benefits professionals and researchers who have been working in this area for a long time and wanting to gain an in-depth understanding of the state-of-the-art, but also helps enlighten a wider audience intending to get acquainted with this exciting topic.

Significance and methodology: Preprocessing the big data for machine learning on TBM performance
Haohan Xiao, Wenkun Yang, Jing Hu, Yunpei Zhang +2 more
2022· Underground Space89doi:10.1016/j.undsp.2021.12.003

This paper addresses the significance of preprocessing big data collected during a tunnel boring machine (TBM) excavation before it is used for machine learning on various TBM performance predictions. The research work is based on two water diversion tunneling projects that cover 29.52 km and 17 051 boring cycles. It has been found that the penetration rate calculated from the raw measured penetration distances exhibits more random behavior owing to their percussive and vibratory behavior of the cutterhead. A moving average method to process the negative instantaneous velocities and a noise reduction filter to deal with signals with abnormal frequencies have been recommended. An index called the drilling efficiency index is introduced to assess the relationships between the mechanical parameters in a boring cycle, whose linear regression coefficient R2 is taken for a preliminary investigation of possible problems requiring preprocessing. The research work defines the irrelevant data whose errors are caused by human or mechanical mistakes, and therefore should be cleaned or amended. These irrelevant data can be divided into five categories: (1) premature cycles, (2) sensor defects, (3) mechanical defects, (4) human interruption, and (5) missing files. A program TBM-Processing has been coded for the recognition and classification of these categories. PDF books generated by the program have been uploaded at GitHub to encourage discussions, collaboration, and upgrading of the data processing work with our peers.

Feedback on a shared big dataset for intelligent TBM Part I: Feature extraction and machine learning methods
Jianbin Li, Zuyu Chen, Xu Li, Liujie Jing +4 more
2023· Underground Space88doi:10.1016/j.undsp.2023.01.001

This review summarizes the research outcomes and findings documented in 45 journal papers using a shared tunnel boring machine (TBM) dataset for performance prediction and boring efficiency optimization using machine learning methods. The big dataset was collected during the Yinsong water diversion project construction in China, covering the tunnel excavation of a 20 km-section with 199 items of monitoring metrics taken with an interval of one second. The research papers were the result of a call for contributions during a TBM machine learning contest in 2019 and covered a variety of topics related to the intelligent construction of TBM. This review comprises two parts. Part I is concerned with the data processing, feature extraction, and machine learning methods applied by the contributors. The review finds that the data-driven and knowledge-driven approaches in extracting important features applied by various authors are diversified, requiring further studies to achieve commonly accepted criteria. The techniques for cleaning and amending the raw data adopted by the contributors were summarized, indicating some highlights such as the importance of sufficiently high frequency of data acquisition (higher than 1 second), classification and standardization for the data preprocessing process, and the appropriate selections of features in a boring cycle. The review finds that both supervised and unsupervised machine learning methods have been utilized by various researchers. The ensemble and deep learning methods have found wide applications. Part I highlights the important features of the individual methods applied by the contributors, including the structures of the algorithm, selection of hyperparameters, and model validation approaches.

Analysis of Effects of CO<sub>2</sub> Injection on Coalbed Permeability: Implications for Coal Seam CO<sub>2</sub> Sequestration
Erlei Su, Yunpei Liang, Quanle Zou, Fanfan Niu +1 more
2019· Energy & Fuels87doi:10.1021/acs.energyfuels.9b01190

A proper understanding of permeability reductions of CH4-containing coal seams after CO2 injection is essential, as coal permeability is the key parameter influencing the efficiency of enhanced coalbed methane recovery with CO2 sequestration and theoretical research on it is lacking. The main objective of this study was to accurately quantify the effects of CO2 injection on coalbed permeability. Therefore, permeability decrease coefficients and permeability rebound and recovery pressures of a binary gas (CH4 + CO2) are proposed based on the Shi–Durucan and extended Langmuir models. Then, the trends of these parameters under the influence of the main influencing factors are detailed. Specifically, the permeability decrease coefficient increased with an increase in CO2 proportion and increased rapidly when the reservoir gas pressure was low. Permeability recovery pressure decreased with an increase in CO2 proportion; the range of decrease was larger at low CO2 proportions. CO2 proportion had little effect on the permeability rebound pressure. Besides, the larger the Langmuir volume constant of CO2, the larger was the permeability decrease coefficient and permeability rebound pressure, and the smaller the permeability recovery pressure. However, the effect of the Langmuir pressure constant on these parameters was relatively weak. Finally, in light of these results, the implications of different characteristics of permeability evolution for CO2 injection pressure adjustment in the process of enhanced coalbed methane recovery with CO2 sequestration are discussed from a macroscopic perspective. The results of this study may provide a reference to select appropriate coal seams and injection pressures for CO2 sequestration.

Landslides Information Extraction Using Object-Oriented Image Analysis Paradigm Based on Deep Learning and Transfer Learning
Heng Lü, Lei Ma, Fu Xiao, Chao Liu +3 more
2020· Remote Sensing86doi:10.3390/rs12050752

How to acquire landslide disaster information quickly and accurately has become the focus and difficulty of disaster prevention and relief by remote sensing. Landslide disasters are generally featured by sudden occurrence, proposing high demand for emergency data acquisition. The low-altitude Unmanned Aerial Vehicle (UAV) remote sensing technology is widely applied to acquire landslide disaster data, due to its convenience, high efficiency, and ability to fly at low altitude under cloud. However, the spectrum information of UAV images is generally deficient and manual interpretation is difficult for meeting the need of quick acquisition of emergency data. Based on this, UAV images of high-occurrence areas of landslide disaster in Wenchuan County and Baoxing County in Sichuan Province, China were selected for research in the paper. Firstly, the acquired UAV images were pre-processed to generate orthoimages. Subsequently, multi-resolution segmentation was carried out to obtain image objects, and the barycenter of each object was calculated to generate a landslide sample database (including positive and negative samples) for deep learning. Next, four landslide feature models of deep learning and transfer learning, namely Histograms of Oriented Gradients (HOG), Bag of Visual Word (BOVW), Convolutional Neural Network (CNN), and Transfer Learning (TL) were compared, and it was found that the TL model possesses the best feature extraction effect, so a landslide extraction method based on the TL model and object-oriented image analysis (TLOEL) was proposed; finally, the TLOEL method was compared with the object-oriented nearest neighbor classification (NNC) method. The research results show that the accuracy of the TLOEL method is higher than the NNC method, which can not only achieve the edge extraction of large landslides, but also detect and extract middle and small landslides accurately that are scatteredly distributed.

Microstructure, mechanical and tribological properties of multilayer Ti-DLC thick films on Al alloys by filtered cathodic vacuum arc technology
Hongshuai Cao, Xue Ye, Hao Li, Fugang Qi +4 more
2020· Materials & Design84doi:10.1016/j.matdes.2020.109320

Low hardness and poor wear resistance are major limitations of Al alloys, which hinder their application in several fields, especially automotive moving parts. DLC can effectively improve hardness and wear resistance of Al alloys, but high residual stress and poor adhesion limit the film thickness. Multilayer thick films (~10 μm) composed of alternating Ti and Ti-DLC layers were successfully deposited on Al alloys. The influence of Ti content on the microstructure, mechanical and tribological properties of the film was emphasized. As the Ti content decreased from 10.42 to 1.35 at.%, the microstructure evolved from a polycrystalline composite film to a nanocrystalline composite film, and then to an amorphous film. The mechanical and tribological properties of the film depended on the microstructure. The amorphous composite film (Ti >6.06 at.%) exhibited better wear resistance than the polycrystalline composite film (Ti <6.06 at.%) due to the higher H/E⁎ (>0.1), H3/E⁎2 (>0.2) and elastic recovery (>60%). When the doped Ti content was 6.06 at.%, the nanocrystalline composite multilayer film showed superior comprehensive performance of high hardness (~23 GPa), high elastic recovery (~69%), low friction coefficient (~0.13) and low wear rate (1.0 × 10−7 mm3/Nm).

Low-frequency vibration control of floating slab tracks using dynamic vibration absorbers
Shengyang Zhu, Jizhong Yang, Hua Yan, Longqing Zhang +1 more
2015· Vehicle System Dynamics82doi:10.1080/00423114.2015.1046460

This study aims to effectively and robustly suppress the low-frequency vibrations of floating slab tracks (FSTs) using dynamic vibration absorbers (DVAs). First, the optimal locations where the DVAs are attached are determined by modal analysis with a finite element model of the FST. Further, by identifying the equivalent mass of the concerned modes, the optimal stiffness and damping coefficient of each DVA are obtained to minimise the resonant vibration amplitudes based on fixed-point theory. Finally, a three-dimensional coupled dynamic model of a metro vehicle and the FST with the DVAs is developed based on the nonlinear Hertzian contact theory and the modified Kalker linear creep theory. The track irregularities are included and generated by means of a time–frequency transformation technique. The effect of the DVAs on the vibration absorption of the FST subjected to the vehicle dynamic loads is evaluated with the help of the insertion loss in one-third octave frequency bands. The sensitivities of the mass ratio of DVAs and the damping ratio of steel-springs under the floating slab are discussed as well, which provided engineers with the DVA's adjustable room for vibration mitigation. The numerical results show that the proposed DVAs could effectively suppress low-frequency vibrations of the FST when tuned correctly and attached properly. The insertion loss due to the attachment of DVAs increases as the mass ratio increases, whereas it decreases with the increase in the damping ratio of steel-springs.

Cumulative settlement of track subgrade in high-speed railway under varying water levels
Renpeng Chen, Jinmiao Chen, Xing Zhao, Xuecheng Bian +1 more
2014· International Journal of Rail Transportation81doi:10.1080/23248378.2014.959083

Water-level variation in the subgrade of high-speed railway influences the cumulative settlement of the subgrade. Full-scale model test on high-speed railway under varying water levels within the subgrade was conducted in this research. Dynamic soil pressures in different depths within the subgrade and cumulative settlements of subgrade were measured under different train speeds. The results demonstrated that the dynamic soil pressure increases significantly after the first wetting-drying cycles and then remains stable. The measured dynamic soil pressure was compared to the requirements in the current design method. Increasing train speed leads to higher cumulative settlement. Furthermore, a modified model is proposed in the article for the determination of cumulative settlement considering the influence of initial stress state, material properties of subgrade, and dynamic stresses of train loadings.

Clopidogrel Plus Aspirin vs Aspirin Alone in Patients With Acute Mild to Moderate Stroke
Hui-Sheng Chen, Yu Cui, Xinhong Wang, Yu-Tong Ma +4 more
2024· JAMA Neurology76doi:10.1001/jamaneurol.2024.0146

Importance: Dual antiplatelet therapy has been demonstrated to be superior to single antiplatelet in reducing recurrent stroke among patients with transient ischemic attack or minor stroke, but robust evidence for its effect in patients with mild to moderate ischemic stroke is lacking. Objective: To evaluate whether dual antiplatelet therapy is superior to single antiplatelet among patients with mild to moderate ischemic stroke. Design, Setting, and Participants: This was a multicenter, open-label, blinded end point, randomized clinical trial conducted at 66 hospitals in China from December 20, 2016, through August 9, 2022. The date of final follow-up was October 30, 2022. The analysis was reported on March 12, 2023. Of 3065 patients with ischemic stroke, 3000 patients with acute mild to moderate stroke within 48 hours of symptom onset were enrolled, after excluding 65 patients who did not meet eligibility criteria or had no randomization outcome. Interventions: Within 48 hours after symptom onset, patients were randomly assigned to receive clopidogrel plus aspirin (n = 1541) or aspirin alone (n = 1459) in a 1:1 ratio. Main Outcomes and Measures: The primary end point was early neurologic deterioration at 7 days, defined as an increase of 2 or more points in National Institutes of Health Stroke Scale (NIHSS) score, but not as a result of cerebral hemorrhage, compared with baseline. The superiority of clopidogrel plus aspirin to aspirin alone was assessed based on a modified intention-to-treat population, which included all randomized participants with at least 1 efficacy evaluation regardless of treatment allocation. Bleeding events were safety end points. Results: Of the 3000 randomized patients, 1942 (64.6%) were men, the mean (SD) age was 65.9 (10.6) years, median (IQR) NIHSS score at admission was 5 (4-6), and 1830 (61.0%) had a stroke of undetermined cause. A total of 2915 patients were included in the modified intention-to-treat analysis. Early neurologic deterioration occurred in 72 of 1502 (4.8%) in the dual antiplatelet therapy group vs 95 of 1413 (6.7%) in the aspirin alone group (risk difference -1.9%; 95% CI, -3.6 to -0.2; P = .03). Similar bleeding events were found between 2 groups. Conclusions and Relevance: Among Chinese patients with acute mild to moderate ischemic stroke, clopidogrel plus aspirin was superior to aspirin alone with regard to reducing early neurologic deterioration at 7 days with similar safety profile. These findings indicate that dual antiplatelet therapy may be a superior choice to aspirin alone in treating patients with acute mild to moderate stroke. Trial Registration: ClinicalTrials.gov Identifier: NCT02869009.

Longitudinal mechanical response of tunnels under active normal faulting
Yafei Qiao, Jie Tang, Guozhao Liu, Manchao He
2022· Underground Space75doi:10.1016/j.undsp.2021.12.002

This paper aims to clarify the mechanism of the longitudinal response of a tunnel under normal faulting via a comprehensive analysis of available experimental data and numerical simulations. Four 1 g condition model tests were reviewed and reanalysed to highlight the key characteristics of the tunnel response under normal faulting: S-shaped deformation and inverted S-shaped bending strain distribution in the longitudinal direction; the main affected zone of faulting is approximately six times the tunnel diameter to the fault plane. A three-dimensional finite element model was also established and verified, followed by a sensitivity analysis of key parameters, including the fault dislocation, dip angle, tunnel rigidity and relative stiffness between the hanging wall and footwall. All results reveal that the longitudinal mechanical response under normal faulting is dominated by a combination of bending, tension, and shearing. Bending and shearing are induced by the large unbalanced rock pressure at the vault in the hanging wall and the inverted arch in the footwall; the value of unbalanced rock pressure is directly proportional to the dislocation but negatively correlated with the dip angle. Although the main part of the tunnel stays in tension, axial compressive strain exists around the fault plane when the dip angle is greater than 70°, which may be related to the ovaling effect of the tunnel. Such an ovaling effect is caused by the compression at the cross-section of the tunnel and may lead to more complicated internal strain.

A Power Allocation Method for Multistack PEMFC System Considering Fuel Cell Performance Consistency
Tianhong Wang, Qi Li, Xiaotong Wang, Weirong Chen +2 more
2020· IEEE Transactions on Industry Applications75doi:10.1109/tia.2020.3001254

The purpose of this work is to design a power allocation method (PAM) for multistack fuel cell system (MFCS). Due to the limitations of technology, large-scale application of proton exchange membrane fuel cell (PEMFC) in the field of rail transportation has not been implemented. Therefore, this study presents an MFCS to promote the use of PEMFCs in the high-power energy market. During the operation of the MFCS, since the output power of the FC varies dynamically with different operation conditions, the performance of each stack is usually inconsistent. A method for evaluating the degree of performance degradation (DOPD) of stacks is presented in this study. In addition, a fuel cell (FC) semiempirical model is also adopted to simulate the effects of aging on the stacks' performance. In order to maintain the uniform performance of stacks and enhance the lifespan of the MFCS, a PAM that considers the DOPD of each stack is presented. Besides, in order to facilitate system expansion, this article proposes a virtual droop control method to realize power splitting among the stacks. Also, a voltage control strategy is presented to compensate for the bus voltage drop caused by the droop control. The effectiveness and practicability of the presented PAM and MFCS are verified on the hardware-in-the-loop test bench constructed by RT-LAB.