Government College University, Lahore

Solution-processed organic photovoltaics (OPV) offer the attractive prospect of low-cost, light-weight and environmentally benign solar energy production. The highest efficiency OPV at present use low-bandgap donor polymers, many of which suffer from problems with stability and synthetic scalability. They also rely on fullerene-based acceptors, which themselves have issues with cost, stability and limited spectral absorption. Here we present a new non-fullerene acceptor that has been specifically designed to give improved performance alongside the wide bandgap donor poly(3-hexylthiophene), a polymer with significantly better prospects for commercial OPV due to its relative scalability and stability. Thanks to the well-matched optoelectronic and morphological properties of these materials, efficiencies of 6.4% are achieved which is the highest reported for fullerene-free P3HT devices. In addition, dramatically improved air stability is demonstrated relative to other high-efficiency OPV, showing the excellent potential of this new material combination for future technological applications.

The pandemic situation with the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from China has endangered human lives. Coronavirus disease 2019 (COVID-19) is presented with asymptomatic, mild, or severe pneumonia-like symptoms. COVID-19 patients with diabetes, chronic obstructive pulmonary disease (COPD), cardiovascular diseases (CVD), hypertension, malignancies, HIV, and other comorbidities could develop a life-threatening situation. SARS-CoV-2 utilizes ACE-2 receptors found at the surface of the host cells to get inside the cell. Certain comorbidities are associated with a strong ACE-2 receptor expression and higher release of proprotein convertase that enhances the viral entry into the host cells. The comorbidities lead to the COVID-19 patient into a vicious infectious circle of life and are substantially associated with significant morbidity and mortality. The comorbid individuals must adopt the vigilant preventive measure and require scrupulous management. In this review, we rigorously focused on the impact of common morbidities in COVID-19 patients and recapitulated the management strategies with recent directions. We found limited resources describing the association of comorbidities in COVID-19; however, our review delineates the broader spectrum of comorbidities with COVID-19 patients.

Energy Storage Technology is one of the major components of renewable energy integration and decarbonization of world energy systems. It significantly benefits addressing ancillary power services, power quality stability, and power supply reliability. However, the recent years of the COVID-19 pandemic have given rise to the energy crisis in various industrial and technology sectors. An integrated survey of energy storage technology development, its classification, performance, and safe management is made to resolve these challenges. The development of energy storage technology has been classified into electromechanical, mechanical, electromagnetic, thermodynamics, chemical, and hybrid methods. The current study identifies potential technologies, operational framework, comparison analysis, and practical characteristics. This proposed study also provides useful and practical information to readers, engineers, and practitioners on the global economic effects, global environmental effects, organization resilience, key challenges, and projections of energy storage technologies. An optimal scheduling model is also proposed. Policies for sustainable adaptation are then described. An extensive list of publications to date in the open literature is canvassed to portray various developments in this area.

Nanotechnology is capturing great interest worldwide due to their stirring applications in various fields. Among nanoparticles (NPs), titanium dioxide (TiO2) NPs have been widely used in daily life and can be synthesized through various physical, chemical, and green methods. Green synthesis is a non-toxic, cost-effective, and eco-friendly route for the synthesis of NPs. Plenty of work has been reported on the green, chemical, physical and biological synthesis of TiO2 NPs and these NPs can be characterized through high tech. instruments. In the present review, dense data have been presented on the comparative synthesis of TiO2 NPs with different characteristics and their wide range of applications. Among the TiO2 NPs synthesis techniques, the green methods have been proven to be efficient than chemical synthesis methods because of the less use of precursors, time-effectiveness, and energy-efficiency during the green synthesis procedures. Moreover, this review describes the types of plants (shrubs, herbs and trees), microorganisms (bacteria, fungi and algae), biological derivatives (proteins, peptides, and starches) employed for the synthesis of TiO2 NPs. The TiO2 NPs can be effectively used for the treatment of polluted water and positively affected the plant physiology especially under abiotic stresses but the response varied with types, size, shapes, doses, duration of exposure, metal species along with other factors. This review also highlights the regulating features and future standpoints for the measurable enrichment in TiO2 NPs product and perspectives of TiO2 NPs reliable application.

Zinc is an imperative micronutrient required for optimum plant growth. Zinc solubilizing bacteria are potential alternatives for zinc supplementation and convert applied inorganic zinc to available forms. This study was conducted to screen zinc solubilizing rhizobacteria isolated from wheat and sugarcane, and to analyze their effect on wheat growth and development. Fourteen exo-polysaccharides producing bacterial isolates of wheat were identified and characterized biochemically as well as on the basis of 16S rRNA gene sequences. Along these, ten identified sugarcane isolates were also screened for zinc solubilizing ability on five different insoluble zinc sources. Out of twenty four, five strains, i.e., EPS 1 (Pseudomonas fragi), EPS 6 (Pantoea dispersa), EPS 13 (Pantoea agglomerans), PBS 2 (E. cloacae) and LHRW1 (Rhizobium sp.) were selected (based on their zinc solubilizing and PGP activities) for pot scale plant experiments. ZnCO3 was used as zinc source and wheat seedlings were inoculated with these five strains, individually, to assess their effect on plant growth and development. The effect on plants was analyzed based on growth parameters and quantifying zinc content of shoot, root and grains using atomic absorption spectroscopy. Plant experiment was performed in two sets. For first set of plant experiments (harvested after one month), maximum shoot and root dry weights and shoot lengths were noted for the plants inoculated with Rhizobium sp. (LHRW1) while E. cloacae (PBS 2) increased both shoot and root lengths. Highest zinc content was found in shoots of E. cloacae (PBS 2) and in roots of P. agglomerans (EPS 13) followed by zinc supplemented control. For second set of plant experiment, when plants were harvested after three months, Pantoea dispersa (EPS 6), P. agglomerans (EPS 13) and E. cloacae (PBS 2) significantly increased shoot dry weights. However, significant increase in root dry weights and maximum zinc content was recorded for Pseudomonas fragi (EPS 1) inoculated plants, isolated from wheat rhizosphere. While maximum zinc content for roots was quantified in the control plants indicating the plant’s inability to transport zinc to grains, supporting accelerated bioavailability of zinc to plant grains with zinc solubilizing rhizobacteria.

Psidium guajava (guava) is well known tropic tree which is abundantly grown for fruit. Many countries have a long history of using guava for medicinal purposes. This plant finds applications for the treatment of diarrhea, dysentery, gastroenteritis, hypertension, diabetes, caries and pain relief and for improvement in locomotors coordination. Its leaf’s extract is being used as a medicine in cough, diarrhea, and oral ulcers and in some swollen gums wound. Its fruit is rich in vitamins A, C, iron, phosphorus and calcium and minerals. It contains high content of organic and inorganic compounds like secondary metabolites e.g. antioxidants, polyphenols, antiviral compounds, anti-inflammatory compounds. The phenolic compounds in guava help to cure cancerous cells and prevent skin aging before time. The presence of terpenes, caryophyllene oxide and p-selinene produces relaxation effects. Guava leaves contain many compounds which act as fungistatic and bacteriostatic agents. Guava has a high content of important antioxidants and has radio-protective ability. Quercetin is considered as most active antioxidant in the guava leaves and is responsible for its spasmolytic activity. Its ethyl acetate extract can stop the germ infection and thymus production. Guava possesses anti-viral, anti-inflammatory, anti-plaque and anti-mutagenic activities. Guava extract shows antinociceptive activity and is also effective in liver damage inflammation and serum production. Ethanolic extract of guava can increase the sperm quality as well as quantity and can be used for the treatment of infertile males.

Brain tumors (BTs) are spreading very rapidly across the world. Every year, thousands of people die due to deadly brain tumors. Therefore, accurate detection and classification are essential in the treatment of brain tumors. Numerous research techniques have been introduced for BT detection as well as classification based on traditional machine learning (ML) and deep learning (DL). The traditional ML classifiers require hand-crafted features, which is very time-consuming. On the contrary, DL is very robust in feature extraction and has recently been widely used for classification and detection purposes. Therefore, in this work, we propose a hybrid deep learning model called DeepTumorNet for three types of brain tumors (BTs)—glioma, meningioma, and pituitary tumor classification—by adopting a basic convolutional neural network (CNN) architecture. The GoogLeNet architecture of the CNN model was used as a base. While developing the hybrid DeepTumorNet approach, the last 5 layers of GoogLeNet were removed, and 15 new layers were added instead of these 5 layers. Furthermore, we also utilized a leaky ReLU activation function in the feature map to increase the expressiveness of the model. The proposed model was tested on a publicly available research dataset for evaluation purposes, and it obtained 99.67% accuracy, 99.6% precision, 100% recall, and a 99.66% F1-score. The proposed methodology obtained the highest accuracy compared with the state-of-the-art classification results obtained with Alex net, Resnet50, darknet53, Shufflenet, GoogLeNet, SqueezeNet, ResNet101, Exception Net, and MobileNetv2. The proposed model showed its superiority over the existing models for BT classification from the MRI images.

Plastics play an important part in every sector of economy all over the world due to their extensive use in agriculture, building and construction, health and consumer goods. They are the backbone of many industries because they are used in the manufacturing of different products including defense materials, sanitary wares, tiles, plastic bottles, artificial leather and different other household items. Plastics are also used in packaging of food items, pharmaceuticals, detergents, and cosmetics. Excessive use of plastics poses a serious threat to the ecosystem and human life on the planet. Plastics accumulation on land and sea has aroused interest to degrade these polymers. There is a need to use adequate biodegradable methods in order to reduce plastics burden from the environment. In order to overcome plastics associated environmental problems, understanding of the interaction between microbes and polymers is of prime importance. Many living organisms but predominantly microorganisms have evolved strategies to survive and degrade plastics. The present review focuses on the types of plastics on the basis of thermal and biodegradable nature, degradation and biodegradation types, types of degradable plastics, characterization of biodegradation, and factors affecting biodegradation. Plastic degradation and bioremediation potential make these microorganisms propitious for green chemistry to eliminate harmful plastics from the ecosystem.

Abstract Lipid oxidation is the principal cause of quality loss in seafood, which is known to contain high amounts of polyunsaturated fatty acids. Such quality deterioration, associated with the development of off‐flavor as well as lowering of nutritive value, can be retarded by incorporation of additives having antioxidative properties. The use of synthetic antioxidants has long been practiced in retarding lipid oxidation. However, due to the potential health concerns of synthetic antioxidants, polyphenolic compounds, which are found in different plants and their manufactured by‐products, have been used as an alternative natural antioxidants to retard lipid oxidation in different seafood systems. Both pure phenolic compounds and crude plant phenolic extracts have been successfully used in delaying oxidation in fish muscle, fish oil, and fish oil‐in‐water emulsions. This article reviews in detail the phenolic antioxidants and their natural sources as well as focuses on the role of pure phenolic compounds and crude plant phenolic extracts on the prevention of lipid oxidation in different seafood systems.

Zinc-air batteries (ZABs) are gaining attention as an ideal option for various applications requiring high-capacity batteries, such as portable electronics, electric vehicles, and renewable energy storage. ZABs offer advantages such as low environmental impact, enhanced safety compared to Li-ion batteries, and cost-effectiveness due to the abundance of zinc. However, early research faced challenges due to parasitic reactions at the zinc anode and slow oxygen redox kinetics. Recent advancements in restructuring the anode, utilizing alternative electrolytes, and developing bifunctional oxygen catalysts have significantly improved ZABs. Scientists have achieved battery reversibility over thousands of cycles, introduced new electrolytes, and achieved energy efficiency records surpassing 70%. Despite these achievements, there are challenges related to lower power density, shorter lifespan, and air electrode corrosion leading to performance degradation. This review paper discusses different battery configurations, and reaction mechanisms for electrically and mechanically rechargeable ZABs, and proposes remedies to enhance overall battery performance. The paper also explores recent advancements, applications, and the future prospects of electrically/mechanically rechargeable ZABs.

Objective: The main objective of the present study was to explore the frequency of Depression, anxiety and stress among university students in Sialkot, Pakistan. Method: Survey research method was used to collect data from three universities of Sialkot by using simple random sampling technique from 500 university students. The study was conducted at GC Women University, Sialkot in total duration of five months from February 2019 to June 2019. A demographic sheet and DASS-21 (Depression, Anxiety Stress Scale) were used to measure the level of depression, anxiety and stress. Data was scored according to the standard scoring procedure for each subscale and for further analysis frequency distribution method was applied through statistical package for social sciences (SPSS. 21). Results: The means of Depression, Anxiety and stress are M=15.08, M=18.24 and M=19.02 respectively. The frequency of depression, anxiety and stress among university students was found 75%, 88.4% and 84.4% respectively. The findings of the study showed the prevalence of Depression within the range of normal (25%), mild (16%), moderate (35.8%), severe (14.6%) and extremely severe (8.6%). The prevalence of anxiety was found to be in the range of normal (11.6%), mild (4.4%), moderate (19.4%), severe (17.8%) and extremely severe (46.8%). Stress was normal (15.6%), mild (33.8%), moderate (35.4%), severe (13.2%) and extremely severe (2.8%). Conclusion: It is concluded that symptoms of anxiety and stress are more prevalent with moderate to extremely severe range than depression in the current sample. These findings suggest urgent need of some preventive measures and interventions to improve the mental health of students. doi: https://doi.org/10.12669/pjms.36.5.1873 How to cite this:Asif S, Mudassar A, Shahzad TZ, Raouf M, Pervaiz T. Frequency of depression, anxiety and stress among university students. Pak J Med Sci. 2020;36(5):971-976. doi: https://doi.org/10.12669/pjms.36.5.1873 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The rapid development of population, industry, and urbanization have generated significant issues including energy consumption and water contamination. Advanced materials are needed to clean up the surroundings and develop potential energy storage devices. Metal sulfides (MSs) nanomaterials are prospective candidates for multidimensional applications in medicine, biology, environmental sciences, and energy production/utilization due to their light absorption, optical characteristics, high specific capacitance, and catalytic/photocatalytic capability. Recent developments showed its use as electrode material for Li, Na, K, and Mg ion batteries, solar cells, and supercapacitors, electrocatalysts for the oxygen/hydrogen evolution reaction, sensors for gases/chemicals, and catalysts/photocatalysts for environmental remediation. Scalable techniques for producing high-quality, low-cost metal sulfides, heterostructures, and hybrids are needed to realize the potential of these interesting materials fully. This review summarizes current achievements in MSs notably, manganese sulfide (MnS), iron sulfide (FeS), cobalt sulfide (CoS), nickel sulfide (NiS), copper sulfide (CuS), zinc sulfide (ZnS), silver sulfide (AgS), cadmium sulfide (CdS), tungsten sufide (WS), tin sulfide (SnS), lead sulfide (PbS), and molybdenum disufide (MOS 2 ) and their efficient physiochemical and biological production to get controlled morphologies, sizes, and compositions.

Phyto-synthesized nanoparticles (NPs) having reduced chemical toxicity have been focused globally and become essential component of nanotechnology recently. We prepared green phytochemically (ginger and garlic) reduced NiO-NPs to replace synthetic bactericidal and catalytic agent in textile industry. NPs were characterized using ultra-violet visible spectroscopy (UV-Vis), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FTIR), energy-dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The synthesis of NPs was confirmed by XRD and UV-Vis having strong absorption at 350 nm with size ranged between 16-52 nm for ginger and 11-59 nm for garlic. Scanning and transmission electron microscopy confirmed pleomorphism with cubic- and more spherical-shaped NPs. Moreover, exact quantities of garlic and ginger extracts (1:3.6 ml) incorporated to synthesize NiO-NPs have been successfully confirmed by FTIR. Phytochemically reduced NPs by garlic presented enhanced bactericidal activity against multiple drug-resistant Staphylococcus aureus at increasing concentrations (0.5, 1.0 mg/50 μl) and also degraded methylene blue (MB) dye efficiently. Conclusively, green synthesized NiO-NPs are impending activists to resolve drug resistance as well as environment friendly catalytic agent that may be opted at industrial scale.

Abstract This study aims to evaluate the impact of internship programs on the professional as well as on personal development and skills of business students in Pakistan. The data of the study consisted of 800 undergraduating business students of 4-year degree programs from 15 universities of Pakistan. The study used structured questionnaire (35 close-ended questions assessed using 5-point Likert scale) comprised of six parts: Part I: Demographic information, Part II: Reasons for participation in internship, and Part III to VI: Assessment of information related to professional and personal growth and skills. The study employed descriptive analysis to evaluate demographic information and central tendencies of the responses. Furthermore, scale measurement analysis is used to check distribution normality of study data and reliability of the questionnaire. The results of the study depict the impact of internship programs on the professional and personal growth and skills of the business students of Pakistan.

In spherical galaxies, binary supermassive black holes (SMBHs) have difficulty reaching sub-parsec separations due to depletion of stars on orbits that intersect the massive binary - the final-parsec problem. Galaxies that form via major mergers are substantially nonspherical, and it has been argued that the centrophilic orbits in triaxial galaxies might provide stars to the massive binary at a high enough rate to avoid stalling. Here we test that idea by carrying out fully self-consistent merger simulations of galaxies containing central SMBHs. We find hardening rates of the massive binaries that are indeed much higher than in spherical models, and essentially independent of the number of particles used in the simulations. Binary eccentricities remain high throughout the simulations. Our results constitute a fully stellar-dynamical solution to the final-parsec problem and imply a potentially high rate of events for low-frequency gravitational wave detectors like LISA.

Polyhydroxyalkanoates (PHAs) are biopolymers with desirable material properties similar to petrochemically derived plastics. PHAs are naturally produced by a wide range of microorganisms as a carbon storage mechanism and can accumulate to significantly high levels. PHAs are an environmentally friendly alternative to their petroleum counterparts because they can be easily degraded, potentially reducing the burden on municipal waste systems. Nevertheless, widespread use of PHAs is not currently realistic due to a variety of factors. One of the major constraints of large-scale PHA production is the cost of carbon substrate for PHA-producing microbes. The cost of production could potentially be reduced with the use of waste carbon from food-related processes. Food wastage is a global issue and therefore harbours immense potential to create valuable bioproducts. This article's main focus is to examine the state of the art of converting food-derived waste into carbon substrates for microbial metabolism and subsequent conversion into PHAs.

Abstract Cobalt oxide nanoparticles (Co 3 O 4 -Nps) have many applications and now a days the green methods of synthesis of these NPs are preferred over other methods because of associated benefits. In this study, Co 3 O 4 -Nps were synthesized by using leaves extract of Populus ciliata (safaida) and cobalt nitrate hexa hydrate as a source of cobalt. The synthesized NPs were analyzed by different techniques such as fourier transform spectroscopy (FTIR), x-ray diffraction (XRD), transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Antibacterial activities of the synthesized Co 3 O 4 -Nps were evaluated against gram negative and gram positive bacteria and found active against Escherichia coli (E. coli), Klebseilla pneumonia (K. pneumonia), Bacillus subtillus (B.subtillus) and Bacillus lichenifermia (B. lichenifermia). The activity results were analyzed statistically by one-way ANOVA, with ‘Dunnett’s Multiple Comparison Test’. The maximum mean activity (21.8 ± 0.7) was found for B. subtilis and minimum mean activity (14.0 ± 0.6) was observed for E. coli.

Recently, development of reliable experimental protocols for synthesis of metal nanoparticles with desired morphologies and sizes has become a major focus of researchers. Green synthesis of metallic nanoparticles has accumulated an ultimate interest over the last decade due to their distinctive properties that make them applicable in various fields of science and technology. Metal nanoparticles that are synthesized by using plants have emerged as nontoxic and ecofriendly. In this study a very cheap and simple conventional heating method was used to obtain the iron nanoparticles (FeNPs) using the leaves extract of Lawsonia inermis and Gardenia jasminoides plant. The iron nanoparticles were characterized by thermal gravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT‐IR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic force microscopy (AFM), and X‐ray diffraction (XRD). The antibacterial activity was studied against Escherichia coli , Salmonella enterica , Proteus mirabilis , and Staphylococcus aureus by using well‐diffusion method.

The majority of the studies addressing human happiness have been conducted with Western Judeo-Christian cultures; other countries with different sociocultural milieus are underrepresented in research investigating this issue. The present work was undertaken to determine the prevalence and predictors of personal well-being in an Eastern Muslim culture, Pakistan. The study also aimed to compare the current ratings of subjective well-being with those obtained from other areas of the world. To make this survey representative of the vast majority of Pakistani people, a total of 1,000 people, with an age range of 16–80, living in diverse areas of Lahore (the provincial capital) were contacted. Ten localities ranging from upper-class areas to congested inner-city locations and to Kacchi Abadies (temporary houses built in caravan) were visited. Apart from demographic information, responses of the survey subjects were collected on multiple dimensions: personality traits, self-esteem, work satisfaction, marital satisfaction, religiosity, and social support. General well-being was assessed using Faces Scale and Ladder Scale of Life Satisfaction. The current findings, consistent with previous worldwide reports, showed that the number of happy people exceeds those who are unhappy, and also that Eastern people are as happy and satisfied as people from many Western countries. Work satisfaction, social support, religious affiliation, social class, income level, and marital status and satisfaction were found to be the better predictors of subjective well-being.

Graphene oxide (GO) was obtained through modified hummers method, and reduced graphene oxide (rGO) was acquired by employing heat treatment. Various concentrations (2.5, 5, 7.5, and 10 wt. %) of silver (Ag) were incorporated in GO nanosheets by adopting hydrothermal approach. Synthesized Ag decorated rGO photocatalyst Ag/rGO was characterized using X-ray diffraction (XRD) to determine phase purity and crystal structure. XRD patterns showed the formation of GO to Ag/rGO. Molecular vibration and functional groups were determined through Fourier Transform Infrared spectroscopy (FTIR). Optical properties and a decrease in bandgap with insertion of Ag were confirmed with UV-Visible (Uv-Vis) spectrophotometer and photoluminescence (PL). Electronic properties and disorders in carbon structures were investigated through Raman spectroscopy that revealed the existence of characteristic bands (D and G). Surface morphology of prepared samples was examined with field emission scanning electron microscope (FESEM). Homogeneous distribution, size, and spherical shape of Ag NPs over rGO sheets were further confirmed with the help of high-resolution transmission electron microscope (HR-TEM). Dye degradation of doped and undoped samples was examined through Uv-Vis spectra. Experimental results indicated that photocatalytic activity of Ag@rGO enhanced with increased doping ratio owing to diminished electron-hole pair recombination. Therefore, it is suggested that Ag@rGO can be used as a beneficial and superior photocatalyst to clean environment and wastewater.