Niğde Ömer Halisdemir Üniversitesi

ABSTRACT This paper presents a new empirical model for single layer drying process, which was verified with selected experimental data. The present model is also compared with other single layer drying models available in the literature, using laboratory as well as field data from literature.

In response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highest-luminosity high-energy lepton collider (FCC-ee) and an energy-frontier hadron collider (FCC-hh), which could, successively, be installed in the same 100 km tunnel. The scientific capabilities of the integrated FCC programme would serve the worldwide community throughout the 21st century. The FCC study also investigates an LHC energy upgrade, using FCC-hh technology. This document constitutes the second volume of the FCC Conceptual Design Report, devoted to the electron-positron collider FCC-ee. After summarizing the physics discovery opportunities, it presents the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan. FCC-ee can be built with today's technology. Most of the FCC-ee infrastructure could be reused for FCC-hh. Combining concepts from past and present lepton colliders and adding a few novel elements, the FCC-ee design promises outstandingly high luminosity. This will make the FCC-ee a unique precision instrument to study the heaviest known particles (Z, W and H bosons and the top quark), offering great direct and indirect sensitivity to new physics.

Drought stress, which causes a decline in quality and quantity of crop yields, has become more accentuated these days due to climatic change. Serious measures need to be taken to increase the tolerance of crop plants to acute drought conditions likely to occur due to global warming. Drought stress causes many physiological and biochemical changes in plants, rendering the maintenance of osmotic adjustment highly crucial. The degree of plant resistance to drought varies with plant species and cultivars, phenological stages of the plant, and the duration of plant exposure to the stress. Osmoregulation in plants under low water potential relies on synthesis and accumulation of osmoprotectants or osmolytes such as soluble proteins, sugars, and sugar alcohols, quaternary ammonium compounds, and amino acids, like proline. This review highlights the role of osmolytes in water-stressed plants and of enzymes entailed in their metabolism. It will be useful, especially for researchers working on the development of drought-resistant crops by using the metabolic-engineering techniques.

Abstract: We review the physics opportunities of the Future Circular Collider, covering its e+e-, pp, ep and heavy ion programmes. We describe the measurement capabilities of each FCC component, addressing the study of electroweak, Higgs and strong interactions, the top quark and flavour, as well as phenomena beyond the Standard Model. We highlight the synergy and complementarity of the different colliders, which will contribute to a uniquely coherent and ambitious research programme, providing an unmatchable combination of precision and sensitivity to new physics.

The physics programme and the design are described of a new collider for particle and nuclear physics, the Large Hadron Electron Collider (LHeC), in which a newly built electron beam of 60 GeV, to possibly 140 GeV, energy collides with the intense hadron beams of the LHC. Compared to the first ep collider, HERA, the kinematic range covered is extended by a factor of twenty in the negative four-momentum squared, Q 2 , and in the inverse Bjorken x , while with the design luminosity of 10 33 cm -2 s -1 the LHeC is projected to exceed the integrated HERA luminosity by two orders of magnitude. The physics programme is devoted to an exploration of the energy frontier, complementing the LHC and its discovery potential for physics beyond the Standard Model with high precision deep inelastic scattering measurements. These are designed to investigate a variety of fundamental questions in strong and electroweak interactions. The LHeC thus continues the path of deep inelastic scattering (DIS) into unknown areas of physics and kinematics. The physics programme also includes electron-deuteron and electron-ion scattering in a ( Q 2 1/ x ) range extended by four orders of magnitude as compared to previous lepton-nucleus DIS experiments for novel investigations of neutron's and nuclear structure, the initial conditions of Quark-Gluon Plasma formation and further quantum chromodynamic phenomena. The LHeC may be realised either as a ring-ring or as a linac-ring collider. Optics and beam dynamics studies are presented for both versions, along with technical design considerations on the interaction region, magnets including new dipole prototypes, cryogenics, RF, and further components. A design study is also presented of a detector suitable to perform high precision DIS measurements in a wide range of acceptance using state-of-the art detector technology, which is modular and of limited size enabling its fast installation. The detector includes tagging devices for electron, photon, proton and neutron detection near to the beam pipe. Civil engineering and installation studies are presented for the accelerator and the detector. The LHeC can be built within a decade and thus be operated while the LHC runs in its high-luminosity phase. It so represents a major opportunity for progress in particle physics exploiting the investment made in the LHC.

Abstract: In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries.

The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation γ-ray spectrometer. AGATA is based on the technique of γ-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a γ ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realisation of γ-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterisation of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximise its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer.

Cyber-attacks represent a potential threat to information security. As rates of data usage and internet consumption continue to increase, cyber awareness turned to be increasingly urgent. This study focuses on the relationships between cyber security awareness, knowledge and behavior with protection tools among individuals in general and across four countries: Israel, Slovenia, Poland and Turkey in particular. Results show that internet users possess adequate cyber threat awareness but apply only minimal protective measures usually relatively common and simple ones. The study findings also show that higher cyber knowledge is connected to the level of cyber awareness, beyond the differences in respondent country or gender. In addition, awareness is also connected to protection tools, but not to information they were willing to disclose. Lastly, findings exhibit differences between the explored countries that affect the interaction between awareness, knowledge, and behaviors. Results, implications, and recommendations for effective based cyber security training programs are presented and discussed.

As an antioxidant, lycopene has acquired importance as it prevents autoxidation of fats and related products. Tomatoes are an important agricultural product that is a great source of lycopene. It contains many vitamins and minerals, fiber, and carbohydrates and is associated with various positive effects on health. The antioxidant potential of tomatoes is substantially explained with lycopene compounds. Diet is a major risk factor for heart diseases which is shown as the most important cause of death in the world. It has been observed that the lycopene taken in the diet has positive effects in many stages of atherosclerosis. The serum lipid levels, endothelial dysfunction, inflammation, blood pressure, and antioxidative potential are mainly affected by lycopene. These natural antioxidants, which can also enhance the nutritional value of foods, may lead to new ways if used in food preservation. In this review study, the antioxidant potential and cardiovascular protection mechanism of lycopene are discussed.

Chitosan films blended with stem, leaf and seed extracts of <italic>Pistacia terebinthus</italic> for active food packaging.

Today’s wireless networks allocate radio resources to users based on the orthogonal multiple access (OMA) principle. However, as the number of users increases, OMA based approaches may not meet the stringent emerging requirements including very high spectral efficiency, very low latency, and massive device connectivity. Nonorthogonal multiple access (NOMA) principle emerges as a solution to improve the spectral efficiency while allowing some degree of multiple access interference at receivers. In this tutorial style paper, we target providing a unified model for NOMA, including uplink and downlink transmissions, along with the extensions to multiple input multiple output and cooperative communication scenarios. Through numerical examples, we compare the performances of OMA and NOMA networks. Implementation aspects and open issues are also detailed.

Water deficit conditions are a bearing on plant growth and development leading to diminished crop productivity. However, improving the crop productivity is need of the time to sustain the food security under ever increasing world population. Drought episodes are increasing with varying intensity and duration. Drought stress imposes alterations in crucial plant growth and developmental processes, including germination, plant height, stem diameter, number of leaves, leaf size and area, dry matter production and partitioning, flower and fruit production, and maturity. Nonetheless, plants show some morphological changes to cope with drought stress by lowering water loss, enhanced water uptake and maintenance of tissue water status. Some plants complete their life cycle early before the onset of drought to escape water deficit conditions. Identification of effects of drought stress on morphological attributes and morphological changes in response to drought can be promising for selection and breeding of drought resistant genotypes.

Conceptual change researchers have made significant progress on two prominent but competing theoretical perspectives regarding knowledge structure coherence. These perspectives can be broadly characterized as (1) knowledge-as-theory perspectives and (2) knowledge-as-elements perspectives. These perspectives can be briefly summarized in terms of the following questions. Is a student’s knowledge most accurately represented as a coherent unified framework of theory-like character (e.g., Carey, 1999; Chi, 2005; Ioannides & Vosniadou, 2002; Wellman & Gelman, 1992)? Or is a student’s knowledge more aptly considered as an ecology of quasi-independent elements (e.g., Clark, 2006; diSessa, Gillespie, & Esterly, 2004; Harrison, Grayson, & Treagust, 1999; Linn, Eylon, & Davis, 2004)? In this review, we clarify these two theoretical perspectives and discuss the educational implications of each. This debate is important because these perspectives implicate radically different pathways for curricular design to help students reorganize their understandings. Historically, the research literature has predominantly supported knowledge-as-theory perspectives. After outlining both perspectives, this paper discusses arguments and educational implications that potentially favor the adoption of knowledgeas- elements perspectives

Natural products, an infinite treasure of bioactive chemical entities, persist as an inexhaustible resource for discovery of drugs. This review article intends to emphasize on one of the naturally occurring flavonoids, astragalin (kaempferol 3-glucoside), which is a bioactive constituent of various traditional medicinal plants such as Cuscuta chinensis . This multifaceted compound is well known for its diversified pharmacological applications such as anti-inflammatory, antioxidant, neuroprotective, cardioprotective, antiobesity, antiosteoporotic, anticancer, antiulcer, and antidiabetic properties. It carries out the aforementioned activities by the regulation and modulation of various molecular targets such as transcription factors (NF- κ B, TNF- α , and TGF- β 1), enzymes (iNOS, COX-2, PGE2, MMP-1, MMP-3, MIP-1 α , COX-2, PGE-2, HK2, AChe, SOD, DRP-1, DDH, PLC γ 1, and GPX), kinases (JNK, MAPK, Akt, ERK, SAPK, I κ B α , PI3K, and PKC β 2), cell adhesion proteins (E-cadherin, vimentin PAR-2, and NCam), apoptotic and antiapoptotic proteins (Beclin-1, Bcl-2, Bax, Bcl-x L , cytochrome c, LC3A/B, caspase-3, caspase-9, procaspase-3, procaspase-8, and IgE), and inflammatory cytokines (SOCS-3, SOCS-5, IL-1 β , IL-4, IL-6, IL-8, IL-13, MCP-1, CXCL-1, CXCL-2, and IFN- γ ). Although researchers have reported multiple pharmacological applications of astragalin in various diseased conditions, further experimental investigations are still mandatory to fully understand its mechanism of action. It is contemplated that astragalin could be subjected to structural optimization to ameliorate its chemical accessibility, to optimize its absorption profiles, and to synthesize its more effective analogues which will ultimately lead towards potent drug candidates.

This paper proposes an iterative synthesis approach to Petri net (PN)-based deadlock prevention policy for flexible manufacturing systems (FMS). Given the PN model (PNM) of an FMS prone to deadlock, the goal is to synthesize a live controlled PNM. Its use for FMS control guarantees its deadlock-free operation and high performance in terms of resource utilization and system throughput. The proposed method is an iterative approach. At each iteration, a first-met bad marking is singled out from the reachability graph of a given PNM. The objective is to prevent this marking from being reached via a place invariant of the PN. A well-established invariant-based control method is used to derive a control place. This process is carried out until the net model becomes live. The proposed method is generally applicable, easy to use, effective, and straightforward although its off-line computation is of exponential complexity. Two FMS are used to show its effectiveness and applicability

A novel dual-mode resonator with square-patch or corner-cut elements located at four corners of a conventional microstrip loop resonator is proposed. One of these patches or corner cuts is called the perturbation element, while the others are called reference elements. In the proposed design method, the transmission zeros are created or eliminated without sacrificing the passband response by changing the perturbation's size depending on the size of the reference elements. A simple transmission-line model is used to calculate the frequencies of the two transmission zeros. It is shown that the nature of the coupling between the degenerate modes determines the type of filter characteristic, whether it is Chebyshev or elliptic. Finally, two dual-mode microstrip bandpass filters are designed and realized using degenerate modes of the novel dual-mode resonator. The filters are evaluated by experiment and simulation with very good agreement.

Climate change and abiotic stress factors are key players in crop losses worldwide. Among which, extreme temperatures (heat and cold) disturb plant growth and development, reduce productivity and, in severe cases, lead to plant death. Plants have developed numerous strategies to mitigate the detrimental impact of temperature stress. Exposure to stress leads to the accumulation of various metabolites, e.g. sugars, sugar alcohols, organic acids and amino acids. Plants accumulate the amino acid 'proline' in response to several abiotic stresses, including temperature stress. Proline abundance may result from de novo synthesis, hydrolysis of proteins, reduced utilization or degradation. Proline also leads to stress tolerance by maintaining the osmotic balance (still controversial), cell turgidity and indirectly modulating metabolism of reactive oxygen species. Furthermore, the crosstalk of proline with other osmoprotectants and signalling molecules, e.g. glycine betaine, abscisic acid, nitric oxide, hydrogen sulfide, soluble sugars, helps to strengthen protective mechanisms in stressful environments. Development of less temperature-responsive cultivars can be achieved by manipulating the biosynthesis of proline through genetic engineering. This review presents an overview of plant responses to extreme temperatures and an outline of proline metabolism under such temperatures. The exogenous application of proline as a protective molecule under extreme temperatures is also presented. Proline crosstalk and interaction with other molecules is also discussed. Finally, the potential of genetic engineering of proline-related genes is explained to develop 'temperature-smart' plants. In short, exogenous application of proline and genetic engineering of proline genes promise ways forward for developing 'temperature-smart' future crop plants.

The extensive usage of open communication networks in power system control causes inevitable time delays. This paper studies impacts of such delays on the stability of one-area and two-area load frequency control (LFC) systems and proposes an analytical method to determine delay margins, the upper bound on the delay for stability. The proposed method first eliminates transcendental terms in characteristic equation of LFC systems without making any approximation and transforms the transcendental characteristic equation into a regular polynomial. The key result of the elimination process is that real roots of the new polynomial correspond to imaginary roots of the transcendental characteristic equation. With the help of new polynomial, it is also possible to determine the delay-dependency of system stability and root tendency with respect to the time delay. An analytical formula is then developed to compute delay margins in terms of system parameters. For a large set of controller gains, delay margins of LFC systems are computed to investigate the qualitative effect of controller gains on the delay margin. Finally, simulations studies are carried out to verify the effectiveness of the proposed method.

Abstract The Large Hadron–Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron–proton and proton–proton operations. This report represents an update to the LHeC’s conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics by extending the accessible kinematic range of lepton–nucleus scattering by several orders of magnitude. Due to its enhanced luminosity and large energy and the cleanliness of the final hadronic states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, this report contains a detailed updated design for the energy-recovery electron linac (ERL), including a new lattice, magnet and superconducting radio-frequency technology, and further components. Challenges of energy recovery are described, and the lower-energy, high-current, three-turn ERL facility, PERLE at Orsay, is presented, which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution, and calibration goals that arise from the Higgs and parton-density-function physics programmes. This paper also presents novel results for the Future Circular Collider in electron–hadron (FCC-eh) mode, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies.

Our previous work presented a Petri net-based iterative synthesis policy for deadlock prevention in flexible manufacturing systems (FMS). Given the Petri net model of an FMS prone to deadlock, it aims to synthesize a live controlled Petri net. Its use for FMS control guarantees its deadlock-free operation and high performance in terms of resource utilization and system throughput. At each iteration, a first-met bad marking is singled out from the reachability graph of the Petri net. A well-established invariant-based control method is used to prevent it from being reached. This process is carried out until the net model becomes live. The method proposed is generally applicable, easy to use, effective, and straightforward, although its off-line computation is of exponential complexity. This paper presents two improvements: (a) using the Petri net reduction approach to simplify very large Petri net models so as to alleviate computation effort; and (2) simplifying the invariant-based control method. A number of FMS deadlock problems from the literature are used to illustrate them.