University of Tulsa

The present study used meta-analytic techniques to test whether trait consistency maximizes and stabilizes at a specific period in the life course. From 152 longitudinal studies, 3,217 test-retest correlation coefficients were compiled. Meta-analytic estimates of mean population test-retest correlation coefficients showed that trait consistency increased from .31 in childhood to .54 during the college years, to .64 at age 30, and then reached a plateau around .74 between ages 50 and 70 when time interval was held constant at 6.7 years. Analysis of moderators of consistency showed that the longitudinal time interval had a negative relation to trait consistency and that temperament dimensions were less consistent than adult personality traits.

<h3>Importance</h3> Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data. <h3>Objective</h3> To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning. <h3>Evidence Review</h3> We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence. <h3>Findings</h3> In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572 000 deaths and 15.2 million DALYs), and stomach cancer (542 000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819 000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601 000 deaths and 17.4 million DALYs), TBL cancer (596 000 deaths and 12.6 million DALYs), and colorectal cancer (414 000 deaths and 8.3 million DALYs). <h3>Conclusions and Relevance</h3> The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer care.

Abstract The purpose of this paper is to examine the usefulness of factor analysis in developing and evaluating personality scales that measure limited domain constructs The approach advocated follows from several assumptions that a single scale ought to measure a single construct, that factor analysis ought to be applied routinely to new personality scales, and that the factors of a scale are important if it can be demonstrated that they are differentially related to other measures A detailed study of the Self‐Monitoring Scale illustrates how factor analysis can help us to understand what a scale measures A second example uses the self‐esteem literature to illustrate how factor analysis can clarify the proliferation of scales within a single content domain Both examples show how factor analysis can be used to identify important conceptual distinctions Confirmatory techniques are also introduced as a means for testing specific hypotheses It is concluded that factor analysis can make an important contribution to programmatic research in personality psychology

Evidence for situational specificity of personality-job performance relations calls for better understanding of how personality is expressed as valued work behavior. On the basis of an interactionist principle of trait activation (R. P. Tett & H. A. Guterman, 2000), a model is proposed that distinguishes among 5 situational features relevant to trait expression (job demands, distracters, constraints, releasers, and facilitators), operating at task, social, and organizational levels. Trait-expressive work behavior is distinguished from (valued) job performance in clarifying the conditions favoring personality use in selection efforts. The model frames linkages between situational taxonomies (e.g., J. L. Holland's [1985] RIASEC model) and the Big Five and promotes useful discussion of critical issues, including situational specificity, personality-oriented job analysis, team building, and work motivation.

The development of a measure of parental stress, the Parental Stress Scale, is presented. All participants (total N = 1276) completed the Parental Stress Scale and some also completed the Parenting Stress Index, a generic measure of stress called the Perceived Stress Scale, relevant measures of emotions and role satisfaction (e.g. loneliness, marital satisfaction, guilt, etc.), and one group completed the Parental Stress Scale twice. Analyses suggested that the Parental Stress Scale is highly reliable, both internally and over time, and related to the general measure of stress. Also, results were consistent across parents of differing parental characteristics, suggesting the stability of scale characteristics. The validity of Parental Stress Scale scores was supported by predicted correlations with measures of relevant emotions and role satisfaction and significant discrimination between mothers of children in treatment for emotional/behavioral problems and developmental disabilities vs mothers of children not receiving treatment. Finally, a factor analysis suggested that a 4-factor structure underlies responses to the Parental Stress Scale, despite its high internal reliability.

Gas-liquid flow in inclined pipes was investigated to determine the erect of pipe inclination angle on liquid holdup and pressure loss. Correlations for liquid holdup and friction factor were developed for predicting pressure gradients for two-phase flow in pipes at all angles for many flow pressure gradients for two-phase flow in pipes at all angles for many flow conditions. Introduction The prediction of pressure drop and liquid holdup occurring during two-phase gas-liquid flow in pipes is of particular interest to the petroleum, chemical, and nuclear industries. In the nuclear industry, two-phase flow occurs in reactor cooling equipment, and liquid holdup greatly affects heat transfer. Two-phase flow occurs frequently in chemical processing, and the design of processing equipment and piping systems requites knowledge of pressure drop, liquid holdup, and often flow pattern. In the petroleum industry, two-phase flow occurs in pipelines and in oil and gas wells. More than one-half the natural gas gathered in the U. S. flows in two-phase flowlines. Most gas-producing wells produce some liquid and most oil wells produce some gas. As the natural reservoir energy is depleted, many wells are equipped with artificial-lift systems such as gas lift. To design these systems, a method of predicting two-phase-flow pressure gradients is required. pressure gradients is required. Although extensive research in two-phase flow has been conducted during the last 25 years, most of this research has concentrated on either horizontal or vertical flow. Several good correlations exist for predicting pressure drop and liquid holdup in either predicting pressure drop and liquid holdup in either horizontal or vertical flow, but these correlations have not been successful when applied to inclined flow. Many gathering lines and long-distance pipelines pass through areas of hilly terrain. This presents no problem in single-phase flow because the potential energy problem in single-phase flow because the potential energy lost going uphill is regained in the downhill section. This is not the case for two-phase flow, because the liquid holdup, and thus the mixture density, are usually much lower in downhill flow. For this reason, pressure recovery in the downhill sections is usually pressure recovery in the downhill sections is usually neglected in the design of two-phase pipelines. The number of directional or inclined wans is increasing as the search for petroleum moves into previously unexplored areas. In offshore drilling, previously unexplored areas. In offshore drilling, several directional wells are usually drilled from one platform for economic reasons. Deviations of 35 deg. to platform for economic reasons. Deviations of 35 deg. to 45 deg. from the vertical are common. In the permafrost areas of Alaska and Canada, the cost of drilling-rig foundations and the difficulty of transportation require that several wells be directionally drilled from one location. Existing vertical-flow correlations frequently fail to predict pressure gradients in these wells within acceptable limits. Gathering lines from offshore wells usually are laid along the sea floor that slopes up to the shore. The elevation pressure gradient in a pipeline with a very small upward inclination from horizontal can be much greater than the frictional pressure gradient. Therefore, in order to predict pressure drop, the liquid holdup must be accurately predicted. The ability to predict liquid holdup also is essential for designing field processing equipment, such as gas-liquid separators. JPT P. 607

Interoception refers to the process by which the nervous system senses, interprets, and integrates signals originating from within the body, providing a moment-by-moment mapping of the body's internal landscape across conscious and unconscious levels. Interoceptive signaling has been considered a component process of reflexes, urges, feelings, drives, adaptive responses, and cognitive and emotional experiences, highlighting its contributions to the maintenance of homeostatic functioning, body regulation, and survival. Dysfunction of interoception is increasingly recognized as an important component of different mental health conditions, including anxiety disorders, mood disorders, eating disorders, addictive disorders, and somatic symptom disorders. However, a number of conceptual and methodological challenges have made it difficult for interoceptive constructs to be broadly applied in mental health research and treatment settings. In November 2016, the Laureate Institute for Brain Research organized the first Interoception Summit, a gathering of interoception experts from around the world, with the goal of accelerating progress in understanding the role of interoception in mental health. The discussions at the meeting were organized around four themes: interoceptive assessment, interoceptive integration, interoceptive psychopathology, and the generation of a roadmap that could serve as a guide for future endeavors. This review article presents an overview of the emerging consensus generated by the meeting.

BACKGROUND: Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase, is a potential alternative to allopurinol for patients with hyperuricemia and gout. METHODS: We randomly assigned 762 patients with gout and with serum urate concentrations of at least 8.0 mg per deciliter (480 micromol per liter) to receive either febuxostat (80 mg or 120 mg) or allopurinol (300 mg) once daily for 52 weeks; 760 received the study drug. Prophylaxis against gout flares with naproxen or colchicine was provided during weeks 1 through 8. The primary end point was a serum urate concentration of less than 6.0 mg per deciliter (360 micromol per liter) at the last three monthly measurements. The secondary end points included reduction in the incidence of gout flares and in tophus area. RESULTS: The primary end point was reached in 53 percent of patients receiving 80 mg of febuxostat, 62 percent of those receiving 120 mg of febuxostat, and 21 percent of those receiving allopurinol (P<0.001 for the comparison of each febuxostat group with the allopurinol group). Although the incidence of gout flares diminished with continued treatment, the overall incidence during weeks 9 through 52 was similar in all groups: 64 percent of patients receiving 80 mg of febuxostat, 70 percent of those receiving 120 mg of febuxostat, and 64 percent of those receiving allopurinol (P=0.99 for 80 mg of febuxostat vs. allopurinol; P=0.23 for 120 mg of febuxostat vs. allopurinol). The median reduction in tophus area was 83 percent in patients receiving 80 mg of febuxostat and 66 percent in those receiving 120 mg of febuxostat, as compared with 50 percent in those receiving allopurinol (P=0.08 for 80 mg of febuxostat vs. allopurinol; P=0.16 for 120 mg of febuxostat vs. allopurinol). More patients in the high-dose febuxostat group than in the allopurinol group (P=0.003) or the low-dose febuxostat group discontinued the study. Four of the 507 patients in the two febuxostat groups (0.8 percent) and none of the 253 patients in the allopurinol group died; all deaths were from causes that the investigators (while still blinded to treatment) judged to be unrelated to the study drugs (P=0.31 for the comparison between the combined febuxostat groups and the allopurinol group). CONCLUSIONS: Febuxostat, at a daily dose of 80 mg or 120 mg, was more effective than allopurinol at the commonly used fixed daily dose of 300 mg in lowering serum urate. Similar reductions in gout flares and tophus area occurred in all treatment groups.

Much social theory takes for granted the core conceit of modern culture, that modern actors—individuals, organizations, nation states—are autochthonous and natural entities, no longer really embedded in culture. Accordingly, while there is much abstract metatheory about “actors” and their “agency,” there is arguably little theory about the topic. This article offers direct arguments about how the modern (European, now global) cultural system constructs the modern actor as an authorized agent for various interests via an ongoing relocation into society of agency originally located in transcendental authority or in natural forces environing the social system. We see this authorized agentic capability as an essential feature of what modern theory and culture call an “actor,” and one that, when analyzed, helps greatly in explaining a number of otherwise anomalous or little analyzed features of modern individuals, organizations, and states. These features include their isomorphism and standardization, their internal decoupling, their extraordinarily complex structuration, and their capacity for prolific collective action.

Although psychologists know a great deal about leadership, persons who make decisions about real leaders seem largely to ignore their accumulated wisdom. In an effort to make past research more accessible, interpretable, and relevant to decision makers, this article defines leadership and then answers nine questions that routinely come up when practical decisions are made about leadership (e.g., whom to appoint, how to evaluate them, when to terminate them.

Seismic data are usually acquired and processed for imaging reflections. This paper describes a method of processing seismic data for imaging discontinuities (e.g., faults and stratigraphic features). One application of this nontraditional process is a 3-D volume, or cube, of coherence coefficients within which faults are revealed as numerically separated surfaces. Figure 1 compares a traditional 3-D reflection amplitude time slice with the results of the new method. To our knowledge, this is the first published method of revealing fault surfaces within a 3-D volume for which no fault reflections have been recorded.

This book is a guide to the use of inverse theory for estimation and conditional simulation of flow and transport parameters in porous media. It describes the theory and practice of estimating properties of underground petroleum reservoirs from measurements of flow in wells, and it explains how to characterize the uncertainty in such estimates. Early chapters present the reader with the necessary background in inverse theory, probability and spatial statistics. The book demonstrates how to calculate sensitivity coefficients and the linearized relationship between models and production data. It also shows how to develop iterative methods for generating estimates and conditional realizations. The text is written for researchers and graduates in petroleum engineering and groundwater hydrology and can be used as a textbook for advanced courses on inverse theory in petroleum engineering. It includes many worked examples to demonstrate the methodologies and a selection of exercises.

BACKGROUND: Episodes of depression are the most frequent cause of disability among patients with bipolar disorder. The effectiveness and safety of standard antidepressant agents for depressive episodes associated with bipolar disorder (bipolar depression) have not been well studied. Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania. METHODS: In this double-blind, placebo-controlled study, we randomly assigned subjects with bipolar depression to receive up to 26 weeks of treatment with a mood stabilizer plus adjunctive antidepressant therapy or a mood stabilizer plus a matching placebo, under conditions generalizable to routine clinical care. A standardized clinical monitoring form adapted from the mood-disorder modules of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, was used at all follow-up visits. The primary outcome was the percentage of subjects in each treatment group meeting the criterion for a durable recovery (8 consecutive weeks of euthymia). Secondary effectiveness outcomes and rates of treatment-emergent affective switch (a switch to mania or hypomania early in the course of treatment) were also examined. RESULTS: Forty-two of the 179 subjects (23.5%) receiving a mood stabilizer plus adjunctive antidepressant therapy had a durable recovery, as did 51 of the 187 subjects (27.3%) receiving a mood stabilizer plus a matching placebo (P=0.40). Modest nonsignificant trends favoring the group receiving a mood stabilizer plus placebo were observed across the secondary outcomes. Rates of treatment-emergent affective switch were similar in the two groups. CONCLUSIONS: The use of adjunctive, standard antidepressant medication, as compared with the use of mood stabilizers, was not associated with increased efficacy or with increased risk of treatment-emergent affective switch. Longer-term outcome studies are needed to fully assess the benefits and risks of antidepressant therapy for bipolar disorder. (ClinicalTrials.gov number, NCT00012558 [ClinicalTrials.gov].).

Spectral decomposition provides a novel means of utilizing seismic data and the discrete Fourier transform (DFT) for imaging and mapping temporal bed thickness and geologic discontinuities over large 3-D seismic surveys. By transforming the seismic data into the frequency domain via the DFT, the amplitude spectra delineate temporal bed thickness variability while the phase spectra indicate lateral geologic discontinuities. This technology has delineated stratigraphic settings (such as channel sands and structural settings involving complex fault systems) in 3-D surveys.

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.

Clarification of the ideas of institution, institutionalization, and institutionalism. Conceives of institutions as controlling patterns of widely varying sorts, relevant to the explanation of, and stabilization of, the behavior of the full range of modern actors.

Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understood. Structural brain differences have been associated with BD, but results from neuroimaging studies have been inconsistent. To address this, we performed the largest study to date of cortical gray matter thickness and surface area measures from brain magnetic resonance imaging scans of 6503 individuals including 1837 unrelated adults with BD and 2582 unrelated healthy controls for group differences while also examining the effects of commonly prescribed medications, age of illness onset, history of psychosis, mood state, age and sex differences on cortical regions. In BD, cortical gray matter was thinner in frontal, temporal and parietal regions of both brain hemispheres. BD had the strongest effects on left pars opercularis (Cohen’s d =−0.293; P =1.71 × 10 −21 ), left fusiform gyrus ( d =−0.288; P =8.25 × 10 −21 ) and left rostral middle frontal cortex ( d =−0.276; P =2.99 × 10 −19 ). Longer duration of illness (after accounting for age at the time of scanning) was associated with reduced cortical thickness in frontal, medial parietal and occipital regions. We found that several commonly prescribed medications, including lithium, antiepileptic and antipsychotic treatment showed significant associations with cortical thickness and surface area, even after accounting for patients who received multiple medications. We found evidence of reduced cortical surface area associated with a history of psychosis but no associations with mood state at the time of scanning. Our analysis revealed previously undetected associations and provides an extensive analysis of potential confounding variables in neuroimaging studies of BD.

Meta-analytic techniques were used to examine the effectiveness of Web-based instruction (WBI) relative to classroom instruction (CI) and to examine moderators of the comparative effectiveness of the 2 delivery media. The overall results indicated WBI was 6% more effective than CI for teaching declarative knowledge, the 2 delivery media were equally effective for teaching procedural knowledge, and trainees were equally satisfied with WBI and CI. However, WBI and CI were equally effective for teaching declarative knowledge when the same instructional methods were used to deliver both WBI and CI, suggesting media effects are spurious and supporting Clark's (1983, 1994) theory. Finally, WBI was 19% more effective than CI for teaching declarative knowledge when Web-based trainees were provided with control, in long courses, and when trainees practiced the training material and received feedback during training. Study limitations and directions for future research are discussed.

Introduction and Background There has been great progress in data assimilation within atmospheric and oceanographic sciences during the last couple of decades. In data assimilation, one aims at merging the information from observations into a numerical model, typically of a geophysical system. A typical example where data assimilation is needed is in weather forecasting. Here, the atmospheric models must take into account the most recent observations of variables such as temperature and atmospheric pressure for better forecasting of the weather in the next time period. A major challenge for these models is that they contain very large numbers of variables. The progress in data assimilation is because of both increased computational power and the introduction of techniques that are capable of handling large amounts of data and more severe nonlinearities. The aim of this paper is to focus on one of these techniques, the ensemble Kalman filter (EnKF). The EnKF has been introduced to petroleum science recently (Lorentzen et al. 2001a) and, in particular, has attracted attention as a promising method for solving the history matching problem. The literature available on the EnKF is now rather overwhelming. We hope that this review will help researchers (and students) working on adapting the EnKF to petroleum applications to find valuable references and ideas, although the number of papers discussing the EnKF is too large to give a complete review. For practitioners, we have cited critical EnKF papers from weather and oceanography. We have also tried to review most of the papers dealing with the EnKF and updating of reservoir models available to the authors by the beginning of 2008. The EnKF is based on the simpler Kalman filter (Kalman 1960). We will start by introducing the Kalman filter. The Kalman filter is an efficient recursive filter that estimates the state of a linear dynamical system from a series of noisy measurements. The Kalman filter is based on a model equation, where the current state of the system is associated with an uncertainty (expressed by a covariance matrix) and an observation equation that relates a linear combination of the states to measurements. The measurements are also associated with uncertainty. The model equations are used to compute a forward step (Eqs. 1 and 2) where the state variables are computed forward in time with the current estimate of the state as initial condition. The observation equations are used in the analysis step (Eqs. 3 through 5) where the estimated value of the state and its uncertainty are corrected to take into account the most recent measurements See, e.g., Cohn (1997), Maybeck (1979), or Stengel (1994) for an introduction to the Kalman filter.

La complexite des innovations a longtemps ete reconnue comme un facteur affectant leur taux d'adoption. On a etudie la relation entre le sentiment de l'efficacite des ordinateurs et la propension des gens a les utiliser. La croyance en l'efficacite des ordinateurs exerce une influence sur la decision de les utiliser, independemment des croyances concernant la valeur instrumentale de l'ordinateur dans tel ou tel cas specifique