Walton Community Hospital

Conventional marine exploration offshore Nile Delta is challenged by shallow heterogeneities and a deep, complex anhydrite layer called the Messinian. These subsurface complexities cause variable illumination and strong diffracted multiples resulting in imaging challenges below the anhydrite on conventional narrow-azimuth towed streamer acquisition because the recording antenna is too small (Figure 1a). Additionally, it has proved difficult to build the detailed depth migration velocity model required to correctly image below the Messinian layer. Multi-azimuth (MAZ) acquisition using time-domain processing however, has been very successful in addressing both the noise and illumination problems in the Nile Delta. The increased azimuthal and crossline offset coverage—bigger antenna—is achieved by acquiring six conventional marine surveys over the same area at 30° sail-line increments (Figure 1b).

'New' and 'old' suppositories (6 months and 30 months since manufacture) containing 800 mg paracetamol, 16 mg codeine phosphate and 12.5 mg buclizine hydrochloride in an identical base were administered to 10 normal volunteers at an interval of 2 weeks. Blood samples were taken at intervals up to 300 minutes after administration for estimation of paracetamol plasma concentrations using high pressure liquid chromatography. Mean peak concentrations were obtained of 4.75 +/- 0.74 mg/ml at 1.75 hours with the new suppositories and of 4.6 +/- 0.67 mg/ml at 2.0 hours with the old suppositories. The difference was not significant. Mean elimination half-life was 4.4 +/- 0.42 hours and 3.73 +/- 0.28 hours, respectively. Again, the difference was not significant, indicating that the absorption characteristics for the suppositories did not appear to deteriorate with ageing for 24 months. Bioavailability data for paracetamol derived from the results were similar to those reported by other workers who studied suppositories containing paracetamol as the only active ingredient. This indicates that the inclusion of codeine phosphate and buclizine hydrochloride in the suppository formulation investigated in the present study did not affect adversely the absorption of paracetamol.

Thank you very

The British Journal of In-service Education has documented most of the key developments in the field of in-service education for over 20 years. This article traces the phenomenon of teachers' centres from their initiation of the 1960s. Using material published in the journal, it illustrates their growth and development – and subsequent decline. It is argued that teachers' centres in Britain were products of a particular history and context. The manner in which the notion was taken and used in several overseas countries is described. The changing patterns in the way in which in-service education/staff development were perceived are critically examined and related to the political and educational contexts of the last two decades

Characterising the acute medical takeEditor -It is always interesting to read about other hospitals' medical take and the similarity to your own hospital's workload (Robbins et al, FHJ June 2014 pp.28-32).However, the authors missed an opportunity to compare their results to others when they suggested little information examined the acute medical take as a whole and instead literature focused on disease entities or appropriateness of scoring systems in isolation.Readers with an interest in acute medicine may like to be directed to the following studies.The Society of Acute Medicine's work with its national 'A Day in the Life of the AMU' Audits started in 2012 and describes the compliance with clinical quality indicators for acute medical units, disease-specifi c conditions, patient fl ow and outcomes.1 St James Hospital in Dublin has interrogated their databases and produced reports describing the acute medical take in several ways -regarding generating severity assessment scores with biochemical data (serum sodium, potassium, urea, albumin, red cell distribution and white blood cell) with a median length of stay of 4.5 days and 30 day mortality of 3.9% in 2010; the weekend and weekday case mix and illness severity; and readmission trends and mortality.2-4 Chelsea and Westminster Hospital have described the severity of presentations with their local Chelsea Early Warning Score and the National Early Warning Score (median score on their assessment unit 0 and 1 respectively).5 York Hospital has described the case mix that presents in their acute medical take with 16,000 admission episodes (cardiovascular, respiratory and falls being the top 3 presentations, median age 71 years) and Edinburgh Royal Infi rmary has described the medical take in terms of presenting symptoms, referral patterns/source and multi-disciplinary interventions.6,7

Drug DosageThe authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication.However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precau tions.This is particularly important when the recommended agent is a new and/or infrequently employed drug.

3D Seismic Imaging by B. L. Biondi. ISBN 1-56080-137-9, Society of Exploration Geophysicists, 2006, 240 pp., US$149 (Member price, US$99). Reflections in the Field—Commemorating the 75th Anniversary of the SEG. ISBN 1-56080-133-6, Society of Exploration Geophysicists, 2005, DVD (1 disc), US$25 (US$15 for members). Ideas of Landscape by M. Johnson. ISBN 978-1-4051-0160-8 Blackwell Publishing, 2007, 242 pp., US$29.95.

Introduction to Petroleum Seismology, by L. T. Ikelle and L. Amundsen. ISBN 1-56080-129-8, SEG, 2005, 679 pp., $189, $124 (members). Information-based Inversion and Processing with Applications by T. Ulrych and M. Sacchi. ISBN 13 978-0-08-044721-6, Elsevier, 403 pp., US$85, €76.95, £52.99. Groundwater Geophysics: A Tool for Hydrogeology, edited by R. Kirsch. ISBN 978-3-540-29383-5, Springer, 2006, 493 pp., $120. A Hand Up: Women Mentoring Women in Science, edited by D. C. Fort. ISBN 0-9634-590-6-6, Association of Women in Science, 2005, 508 pp., $34.95. Introduction to Mineral Exploration, 2nd Edition, edited by C. J. Moon, M. K. G. Whateley, and A. M. Evans. ISBN-10 1-4051-1317-0, Blackwell, 2006, 489 pp., $84.95.

Multiple Attenuation, edited by Arthur B. Weglein and William H. Dragoset. ISBN 1-56080-131-X, SEG Geophysics Reprint Series No. 23, 2005, 1042 pp., $69 (nonmembers: $99). Exploring Stone Walls—A Field Guide to New England's Stone Walls, by R. M. Thorson. ISBN 0-8027-7708-2, Walker and Co., 2005, 187 pp., $14. Volcanoes and the Environment, edited by Joan Marti and Gerald G. J. Ernst. ISBN 0-521-59254-2. Cambridge, 2005, 488 pp., $90.

The Volcano Adventure Guide, by Rosaly Lopes. ISBN 0-521-55453-5, Cambridge, 2005, 368 pp. $50.

The Volcano Adventure Guide, by Rosaly Lopes. ISBN 0-521-55453-5, Cambridge University Press, 2005, 368 pp. $50. Seismic Signatures and Analysis of Reflection data in Anisotropic Media, by Ilya Tsvankin. ISBN 0950-1401 (Series), 0-08-044618-3 (paperback volume), Elsevier, 2005, Handbook of Geophysical Exploration: Seismic Exploration v.29, 436 pp., $102. Ground-Penetrating Radar for Archaeology by Lawrence B. Conyers. ISBN 0-7591-0772-6, Alta Mira Press, 2004, 173 pp., $85. Parameter Estimation and Inverse Problems, by Richard C. Aster, Brian Borchers and Clifford H. Thurber. ISBN 0-12-065604-3, Elsevier, 2005, 301 pp., $79.95.

Dowsing: A Journey Beyond Our Five Senses, by Hamish Miller. ISBN 0-8027-1430-7, Walker, 2004, 57 pp., $10. Elements of a Random Walk: An Introduction for Advanced Students and Researchers, by Joseph Rudnick and George Gaspari. ISBN 0-521-82891-0, Cambridge, 2004, 346 pp., $65. Seismic While Drilling: Fundamentals of Drill-Bit Seismic for Exploration, Handbook of Geophysical Exploration: Seismic Exploration v.35, by Flavio Poletto and Francesco Miranda. ISBN 0950-1401 (Series), 0-080-43928-4 (Volume), Elsevier, 2004, 520 pp., $140. Nobel Laureates and Twentieth-Century Physics, by Mauro Dardo. ISBN 0-521-54008-9, Cambridge, 2005, 546 pp. $39.99.

JOHRNAL concentrate available resources into fewer and larger units."Mr. Roper's report was dealing with the office of Health Economics' latest publication Building for Health.This wellconsidered document, the result of wideseeking research, seriously challenges the concept of huge hospitals and suggests that resources would be better employed in the development of about 1,000 community care units.Any one properly interested in the future pattern of hospitals (and therefore in the future pattern of medical care because the two are intimately related) would know that the subject is very much open and the decisions involved are ones that will profoundly affect all of us, both as doctors and as potential patients for the next half century or more.May I ask, therefore, through your col- umns if the originator of this press pro- nouncement will reveal himself, and also the authority on which he bases his "wis- dom."His pronouncement as quoted by Mr. Roper is at best irresponsible, and perhaps he will see fit to withdraw it.