NobleBlocks
Yıldız Technical University logo

Yıldız Technical University

UniversityIstanbul, Türkiye

Research output, citation impact, and the most-cited recent papers from Yıldız Technical University (Türkiye). Aggregated across the NobleBlocks index of 300M+ scholarly works.

Total works
28.3K
Citations
779.6K
h-index
227
i10-index
17.9K
Also known as
Yıldız Technical UniversityYıldız Teknik Üniversitesi

Top-cited papers from Yıldız Technical University

Centrality dependence of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>π</mml:mi></mml:math>,<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>K</mml:mi></mml:math>, and<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>p</mml:mi></mml:math>production in Pb-Pb collisions at<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>N</mml:mi><mml:mi>N</mml:mi></mml:mrow></mml:msub></mml:msqrt><mml:mo>=</mml:mo><mml:mn>2.76</mml:mn></mml:mrow></mml:math>TeV
B. Abelev, J. Adam, D. Adamová, A. Adare +4 more
2013· Physical Review C653doi:10.1103/physrevc.88.044910

In this paper measurements are presented of ${\ensuremath{\pi}}^{\ifmmode\pm\else\textpm\fi{}}$, ${K}^{\ifmmode\pm\else\textpm\fi{}}$, $p$, and $\overline{p}$ production at midrapidity ($|y|&lt;0.5$), in Pb-Pb collisions at $\sqrt{{s}_{NN}}=2.76$ TeV as a function of centrality. The measurement covers the transverse-momentum (${p}_{T}$) range from 100, 200, and 300 MeV/$c$ up to 3, 3, and 4.6 GeV/$c$ for $\ensuremath{\pi}$, $K$, and $p$, respectively. The measured ${p}_{T}$ distributions and yields are compared to expectations based on hydrodynamic, thermal and recombination models. The spectral shapes of central collisions show a stronger radial flow than measured at lower energies, which can be described in hydrodynamic models. In peripheral collisions, the ${p}_{T}$ distributions are not well reproduced by hydrodynamic models. Ratios of integrated particle yields are found to be nearly independent of centrality. The yield of protons normalized to pions is a factor $\ensuremath{\sim}$1.5 lower than the expectation from thermal models.

Higher Harmonic Anisotropic Flow Measurements of Charged Particles in Pb-Pb Collisions at<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>N</mml:mi><mml:mi>N</mml:mi></mml:mrow></mml:msub></mml:msqrt><mml:mo>=</mml:mo><mml:mn>2.76</mml:mn><mml:mtext> </mml:mtext><mml:mtext> </mml:mtext><mml:mi>TeV</mml:mi></mml:math>
K. Aamodt, B. Abelev, A. Abrahantes Quintana, D. Adamová +4 more
2011· Physical Review Letters641doi:10.1103/physrevlett.107.032301

We report on the first measurement of the triangular v3, quadrangular v4, and pentagonal v5 charged particle flow in Pb-Pb collisions at sqrt(s(NN)) = 2.76 TeV measured with the ALICE detector at the CERN Large Hadron Collider. We show that the triangular flow can be described in terms of the initial spatial anisotropy and its fluctuations, which provides strong constraints on its origin. In the most central events, where the elliptic flow v2 and v3 have similar magnitude, a double peaked structure in the two-particle azimuthal correlations is observed, which is often interpreted as a Mach cone response to fast partons. We show that this structure can be naturally explained from the measured anisotropic flow Fourier coefficients.

Entrepreneurial characteristics amongst university students
Yonca Gürol, Nuray Atsan
2006· Education + Training593doi:10.1108/00400910610645716

Purpose The purpose of this research is to explore the entrepreneurship profile of Turkish university students and to make an evaluation for their entrepreneurship orientation by comparing them with non‐entrepreneurially inclined students. Design/methodology/approach In this study, six traits, namely need for achievement, locus of control, risk taking propensity, tolerance for ambiguity, innovativeness and self‐confidence, are used to define the entrepreneurial profile of students. The study is conducted on a random sample of fourth year university students ( n = 400) from two Turkish universities. The question “what are you planning to do after graduation?” was asked to students in order to discriminate between those who are entrepreneurially inclined and those who are not. Respondents who have a response saying that “I'm planning to form my own business venture” are accepted as potential entrepreneurs. Then, the entrepreneurial traits of these students are subjected to a comparative analysis with other students who do not plan to start their own businesses, and thus are not included in the group of potential entrepreneurs. In short, a 40‐item questionnaire is administered to students, with questions related to demographic variables, entrepreneurial inclination, and six entrepreneurial traits above cited (with Likert type items). Findings The results of the t ‐tests showed that, except for tolerance for ambiguity and self‐confidence, all entrepreneurial traits are found to be higher in entrepreneurially inclined students, as compared to entrepreneurially non‐inclined students. That is, these students are found to have higher risk taking propensity, internal locus of control, higher need for achievement and higher innovativeness. Research limitations/implications The study comprises fourth year students only, and the percentage of students in the sample who wish to be entrepreneurs is quite low (18 per cent). Also, there are only two universities included in the sample. Further study can be conducted on a wider basis to lead to more general conclusions. Practical implications This study provides insight into entrepreneurship education, as to which entrepreneurial characteristics can be developed to raise good entrepreneurs. Originality/value This study contributes to understanding the differences between characteristics of entrepreneurially inclined and non‐inclined students at the edge of graduation.

Microfluidic Paper-Based Analytical Devices: From Design to Applications
Eka Noviana, Tuğba Özer, Cody S. Carrell, Jeremy Link +3 more
2021· Chemical Reviews592doi:10.1021/acs.chemrev.0c01335

Microfluidic paper-based analytical devices (μPADs) have garnered significant interest as a promising analytical platform in the past decade. Compared with traditional microfluidics, μPADs present unique advantages, such as easy fabrication using established patterning methods, economical cost, ability to drive and manipulate flow without equipment, and capability of storing reagents for various applications. This Review aims to provide a comprehensive review of the field, highlighting fabrication methods available to date with their respective advantages and drawbacks, device designs and modifications to accommodate different assay needs, detection strategies, and the growing applications of μPADs. Finally, we discuss how the field needs to continue moving forward to realize its full potential.

Governance and sustainability
Güler Aras, David Crowther
2008· Management Decision510doi:10.1108/00251740810863870

Purpose The purpose of this paper is to show that corporate governance is fundamental to the continuing operation of any corporation; hence much attention has been paid to the procedures of such governance. Similarly sustainability is fundamental to the continuing operation of any corporation, and is arguably the fashionable concept of the moment. While it is clear what is generally meant by corporate governance it is much less clear what is meant by sustainability and the paper starts by investigating this concept. Design/methodology/approach For two such fundamental concepts however it would seem that there should be a relationship between the two, although little work has been undertaken on exploring this relationship. The central part of this paper is therefore based upon an exploration of the relationship between governance and sustainability, by investigating the FTSE100 companies and their corporate governance policies. Findings This analysis found some strengths – and hence cause for optimism – and some weaknesses – and hence cause for concern. Areas where further work is needed are identified. Research limitations/implications The paper has implications in enhancing the understanding of the necessary components of corporate governance, although it is necessarily limited by the size of the sample. Originality/value This paper increases the understanding of the relationship between corporate governance, sustainability and sustainable development.

pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks
Ege Ülgen, Ozan Özışık, Osman Uğur Sezerman
2019· Frontiers in Genetics499doi:10.3389/fgene.2019.00858

Pathway analysis is often the first choice for studying the mechanisms underlying a phenotype. However, conventional methods for pathway analysis do not take into account complex protein-protein interaction information, resulting in incomplete conclusions. Previously, numerous approaches that utilize protein-protein interaction information to enhance pathway analysis yielded superior results compared to conventional methods. Hereby, we present pathfindR, another approach exploiting protein-protein interaction information and the first R package for active-subnetwork-oriented pathway enrichment analyses for class comparison omics experiments. Using the list of genes obtained from an omics experiment comparing two groups of samples, pathfindR identifies active subnetworks in a protein-protein interaction network. It then performs pathway enrichment analyses on these identified subnetworks. To further reduce the complexity, it provides functionality for clustering the resulting pathways. Moreover, through a scoring function, the overall activity of each pathway in each sample can be estimated. We illustrate the capabilities of our pathway analysis method on three gene expression datasets and compare our results with those obtained from three popular pathway analysis tools. The results demonstrate that literature-supported disease-related pathways ranked higher in our approach compared to the others. Moreover, pathfindR identified additional pathways relevant to the conditions that were not identified by other tools, including pathways named after the conditions.

A turbulent jet in crossflow analysed with proper orthogonal decomposition
Knud Erik Meyer, JAKOB M. PEDERSEN, Oktay Özcan
2007· Journal of Fluid Mechanics442doi:10.1017/s0022112007006143

Detailed instantaneous velocity fields of a jet in crossflow have been measured with stereoscopic particle image velocimetry (PIV). The jet originated from a fully developed turbulent pipe flow and entered a crossflow with a turbulent boundary layer. The Reynolds number based on crossflow velocity and pipe diameter was 2400 and the jet to crossflow velocity ratios were R =3.3 and R =1.3. The experimental data have been analysed by proper orthogonal decomposition (POD). For R =3.3, the results in several different planes indicate that the wake vortices are the dominant dynamic flow structures and that they interact strongly with the jet core. The analysis identifies jet shear-layer vortices and finds that these vortical structures are more local and thus less dominant. For R =1.3, on the other hand, jet shear-layer vortices are the most dominant, while the wake vortices are much less important. For both cases, the analysis finds that the shear-layer vortices are not coupled to the dynamics of the wake vortices. Finally, the hanging vortices are identified and their contribution to the counter-rotating vortex pair (CVP) and interaction with the newly created wake vortices are described.

Centrality determination of Pb-Pb collisions at<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>N</mml:mi><mml:mi>N</mml:mi></mml:mrow></mml:msub></mml:msqrt><mml:mo>=</mml:mo><mml:mn>2.76</mml:mn></mml:mrow></mml:math>TeV with ALICE
B. Abelev, J. Adam, D. Adamová, A. Adare +4 more
2013· Physical Review C435doi:10.1103/physrevc.88.044909

This publication describes the methods used to measure the centrality of inelastic Pb-Pb collisions at a center-of-mass energy of 2.76 TeV per colliding nucleon pair with ALICE. The centrality is a key parameter in the study of the properties of QCD matter at extreme temperature and energy density, because it is directly related to the initial overlap region of the colliding nuclei. Geometrical properties of the collision, such as the number of participating nucleons and the number of binary nucleon-nucleon collisions, are deduced from a Glauber model with a sharp impact parameter selection and shown to be consistent with those extracted from the data. The centrality determination provides a tool to compare ALICE measurements with those of other experiments and with theoretical calculations.

Optimal Household Appliances Scheduling Under Day-Ahead Pricing and Load-Shaping Demand Response Strategies
Nikolaos G. Paterakis, Ozan Erdinç, Anastasios G. Bakirtzis, João P. S. Catalào
2015· IEEE Transactions on Industrial Informatics426doi:10.1109/tii.2015.2438534

In this paper, a detailed home energy management system structure is developed to determine the optimal day-ahead appliance scheduling of a smart household under hourly pricing and peak power-limiting (hard and soft power limitation)-based demand response strategies. All types of controllable assets have been explicitly modeled, including thermostatically controllable (air conditioners and water heaters) and nonthermostatically controllable (washing machines and dishwashers) appliances, together with electric vehicles (EVs). Furthermore, an energy storage system (ESS) and distributed generation at the end-user premises are taken into account. Bidirectional energy flow is also considered through advanced options for EV and ESS operation. Finally, a realistic test-case is presented with a sufficiently reduced time granularity being thoroughly discussed to investigate the effectiveness of the model. Stringent simulation results are provided using data gathered from real appliances and real measurements.

Coping with antibiotic resistance: combining nanoparticles with antibiotics and other antimicrobial agents
Adil Allahverdiyev, Kateryna Kon, Emrah Şefik Abamor, Malahat Bagirova +1 more
2011· Expert Review of Anti-infective Therapy403doi:10.1586/eri.11.121

The worldwide escalation of bacterial resistance to conventional medical antibiotics is a serious concern for modern medicine. High prevalence of multidrug-resistant bacteria among bacteria-based infections decreases effectiveness of current treatments and causes thousands of deaths. New improvements in present methods and novel strategies are urgently needed to cope with this problem. Owing to their antibacterial activities, metallic nanoparticles represent an effective solution for overcoming bacterial resistance. However, metallic nanoparticles are toxic, which causes restrictions in their use. Recent studies have shown that combining nanoparticles with antibiotics not only reduces the toxicity of both agents towards human cells by decreasing the requirement for high dosages but also enhances their bactericidal properties. Combining antibiotics with nanoparticles also restores their ability to destroy bacteria that have acquired resistance to them. Furthermore, nanoparticles tagged with antibiotics have been shown to increase the concentration of antibiotics at the site of bacterium-antibiotic interaction, and to facilitate binding of antibiotics to bacteria. Likewise, combining nanoparticles with antimicrobial peptides and essential oils generates genuine synergy against bacterial resistance. In this article, we aim to summarize recent studies on interactions between nanoparticles and antibiotics, as well as other antibacterial agents to formulate new prospects for future studies. Based on the promising data that demonstrated the synergistic effects of antimicrobial agents with nanoparticles, we believe that this combination is a potential candidate for more research into treatments for antibiotic-resistant bacteria.

Driver Behavior Analysis for Safe Driving: A Survey
Sinan Kaplan, M. Amaç Güvensan, A. Gökhan Yavuz, Yasin Karalurt
2015· IEEE Transactions on Intelligent Transportation Systems393doi:10.1109/tits.2015.2462084

Driver drowsiness and distraction are two main reasons for traffic accidents and the related financial losses. Therefore, researchers have been working for more than a decade on designing driver inattention monitoring systems. As a result, several detection techniques for the detection of both drowsiness and distraction have been proposed in the literature. Some of these techniques were successfully adopted and implemented by the leading car companies. This paper discusses and provides a comprehensive insight into the well-established techniques for driver inattention monitoring and introduces the use of most recent and futuristic solutions exploiting mobile technologies such as smartphones and wearable devices. Then, a proposal is made for the active of such systems into car-to-car communication to support vehicular ad hoc network's (VANET's) primary aim of safe driving. We call this approach the dissemination of driver behavior via C2C communication. Throughout this paper, the most remarkable studies of the last five years were examined thoroughly in order to reveal the recent driver monitoring techniques and demonstrate the basic pros and cons. In addition, the studies were categorized into two groups: driver drowsiness and distraction. Then, research on the driver drowsiness was further divided into two main subgroups based on the exploitation of either visual features or nonvisual features. A comprehensive compilation, including used features, classification methods, accuracy rates, system parameters, and environmental details, was represented as tables to highlight the (dis)advantages and/or limitations of the aforementioned categories. A similar approach was also taken for the methods used for the detection of driver distraction.

Slater-Pauling behavior in LiMgPdSn-type multifunctional quaternary Heusler materials: Half-metallicity, spin-gapless and magnetic semiconductors
K. Özdoğan, E. Şaşıoğlu, I. Galanakis
2013· Journal of Applied Physics391doi:10.1063/1.4805063

We employ ab-initio electronic structure calculations to study 60 LiMgPdSn-type (also known as LiMgPdSb-type) quaternary Heusler compounds. All compounds obey the Slater-Pauling rule with diverse electronic and magnetic properties. 41 compounds are found to be half-metals, 8 spin-gapless semiconductors, and 9 semiconductors. CoVTiAl and CrVTiAl compounds are identified as ferromagnetic and antiferromagnetic semiconductors, respectively, with large energy gaps in both spin directions. All magnetic compounds are expected to have high Curie temperatures making them suitable for spintronics/magnetoelectronics applications.

Managing corporate performance
Güler Aras, Aslı Aybars, Özlem Kutlu Furtuna
2010· International Journal of Productivity and Performance Management391doi:10.1108/17410401011023573

Purpose Corporate social responsibility is important and fundamental to the sustainable operations of corporations. Similarly financial performance is undoubtedly fundamental to the continuing operating of any corporation. This paper aims to investigate the relationship between corporate social responsibility and firm financial performance. Design/methodology/approach The main part of this paper is based upon an exploration of the relationship between corporate social responsibility and financial performance in developing countries. The authors do this by investigating the Istanbul Stock Exchange (ISE) 100 index companies and their social responsibility policy and financial indicators. The relationship between CSR and financial performance is empirically examined between 2005 and 2007 with different approaches and measurement methods. The authors show that some causality is related to lagging between periods for financial performance and CSR. Based upon previous empirical studies, this study conducts the analysis based on the assumption that there may be a relationship between firm size, profitability, risk level and CSR. Findings In doing this analysis the authors found a relationship between firm size and corporate social responsibility. However the authors were not able to find any significant relationship between corporate social responsibility and financial performance/profitability. Research limitations/implications The paper has implications in enhancing the understanding of performance management through understanding the relationship between corporate social responsibility and financial performance particularly in a developing country, although it is necessarily limited by the size of the sample. Originality/value This paper increases the understanding of the relationship between corporate social responsibility and financial performance. This research is also the first research that has examined Turkish companies.

Antimicrobial Effects of TiO <sub>2</sub> and Ag <sub>2</sub> O Nanoparticles Against Drug-Resistant Bacteria and <i>Leishmania</i> Parasites
Adil Allahverdiyev, Emrah Şefik Abamor, Malahat Bagirova, Miriam Rafailovich
2011· Future Microbiology390doi:10.2217/fmb.11.78

Nanotechnology is the creation of functional materials, devices and systems at atomic and molecular scales (1-100 nm), where properties differ significantly from those at a larger scale. The use of nanotechnology and nanomaterials in medical research is growing rapidly. Recently, nanotechnologic developments in microbiology have gained importance in the field of chemotherapy. Bacterial strains that are resistant to current antibiotics have become serious public health problems that raise the need to develop new bactericidal materials. Metal oxide nanoparticles, especially TiO(2) and Ag(2)O nanoparticles, have demonstrated significant antibacterial activity. Therefore, it is thought that this property of metal oxide nanoparticles could effectively be used as a novel solution strategy. In this review, we focus on the unique properties of nanoparticles, their mechanism of action as antibacterial agents and recent studies in which the effects of visible and UV-light induced TiO(2) and Ag(2)O nanoparticles on drug-resistant bacteria have been documented. In addition, from to previous results of our studies, antileishmanial effects of metal oxide nanoparticles are also demonstrated, indicating that metal oxide nanoparticles can also be effective against eukaryotic infectious agents. Conversely, despite their significant potential in antimicrobial applications, the toxicity of metal oxide nanoparticles restricts their use in humans. However, recent studies infer that metal oxide nanoparticles have considerable potential to be the first-choice for antibacterial and antiparasitic applications in the future, provided that researchers can bring new ideas in order to cope with their main problem of toxicity.

Sulfur Chemistry in Polymer and Materials Science
Hatice Mutlu, Ezgi Berfin Ceper, Xiaohui Li, Yang Jing-mei +3 more
2018· Macromolecular Rapid Communications379doi:10.1002/marc.201800650

Sulfur and its functional groups are major players in an area of exciting research taking place in modern polymer and materials science, both in academia and industry. In fact, manifold sulfur-based reactions that are both exceptionally versatile as well as tremendously useful have been implemented, and further utilized for the design and preparation of polymeric materials that lead to a plethora of applications ranging from medicine to optics and nanotechnology to separation science. Hence, within this review, an overview of strategies and developments used over the last 5 years to reinforce the importance of the sulfur functional group in modern polymer and materials science is presented. In particular, many important references in the primary literature of sulfur chemistry are referred to, including thiol-ene, thiol-yne, thiol-Michael addition, disulfide cross-linking, and thiol-disulfide exchange, among others, by explaining and illustrating the important principles. Last but not least, the grand aim to underpin the importance of sulfur in modern polymer and materials science is achieved by presenting selected examples in diverse fields and postulating the respective potential for real-world applications.

Analysis and Mitigation of Power Quality Issues in Distributed Generation Systems Using Custom Power Devices
Eklas Hossain, Mehmet Rıda Tür, Sanjeevikumar Padmanaban, Selim Ay +1 more
2018· IEEE Access368doi:10.1109/access.2018.2814981

This paper discusses the power quality issues for distributed generation systems based on renewable energy sources, such as solar and wind energy. A thorough discussion about the power quality issues is conducted here. This paper starts with the power quality issues, followed by discussions of basic standards. A comprehensive study of power quality in power systems, including the systems with dc and renewable sources is done in this paper. Power quality monitoring techniques and possible solutions of the power quality issues for the power systems are elaborately studied. Then, we analyze the methods of mitigation of these problems using custom power devices, such as D-STATCOM, UPQC, UPS, TVSS, DVR, etc., for micro grid systems. For renewable energy systems, STATCOM can be a potential choice due to its several advantages, whereas spinning reserve can enhance the power quality in traditional systems. At Last, we study the power quality in dc systems. Simpler arrangement and higher reliability are two main advantages of the dc systems though it faces other power quality issues, such as instability and poor detection of faults.

A comprehensive review of fuzzy multi criteria decision making methodologies for energy policy making
İ̇hsan Kaya, Murat Çolak, Fulya Terzi
2019· Energy Strategy Reviews349doi:10.1016/j.esr.2019.03.003

Energy policy making is one of the most significant issues for countries and it can be evaluated by using multi-criteria decision making (MCDM) methods. The energy decision and policy-making problems include selecting among energy alternatives, evaluating energy supply technologies, determining energy policy and energy planning. There is a wide range of studies about energy decision-making problems in the literature and different types of energy alternatives are considered in these studies. The MCDM methods are used as effective tools in order to solve energy decision-making problems since they evaluate alternatives with different perspectives in terms of several conflicting criteria. In this context, the fuzzy set theory (FST) that expresses uncertainties in human opinions, can be successfully used together with the MCDM methods to get more sensitive, concrete and realistic results. This paper aims to present a comprehensive review and bring together existing literature and the most recent advances to lead researchers about the methodologies and applications of fuzzy MCDM in the energy field. For this aim, a large number of papers that use fuzzy MCDM methods to solve energy policy and decision making problems have been analyzed with respect to some characteristics such as types of fuzzy sets, year, journal, fuzzy MCDM method, country and document type. The results of this study indicate that fuzzy Analytic Hierarchy Process (AHP), as an individual tool or by integrating with another MCDM method, is the most applied MCDM method and type-1 fuzzy sets are the most preferred type of fuzzy sets. Additionally, Turkey and China are countries which have the highest number of publications related to fuzzy MCDM methods in energy-related problems.

Dynamic Modeling, Design, and Simulation of a Combined PEM Fuel Cell and Ultracapacitor System for Stand-Alone Residential Applications
M. Uzunoglu, Mohammad Saad Alam
2006· IEEE Transactions on Energy Conversion331doi:10.1109/tec.2006.875468

The available power generated from a fuel cell (FC) power plant may not be sufficient to meet sustained load demands, especially during peak demand or transient events encountered in stationary power plant applications. An ultracapacitor (UC) bank can supply a large burst of power, but it cannot store a significant amount of energy. The combined use of FC and UC has the potential for better energy efficiency, reducing the cost of FC technology, and improved fuel usage. In this paper, we present an FC that operates in parallel with a UC bank. A new dynamic model and design methodology for an FCand UC-based energy source for stand-alone residential applications has been developed. Simulation results are presented using MATLAB, Simulink, and SimPowerSystems environments based on the mathematical and dynamic electrical models developed for the proposed system

Advances in Paper-Based Analytical Devices
Tuğba Özer, Catherine McMahon, Charles S. Henry
2020· Annual Review of Analytical Chemistry324doi:10.1146/annurev-anchem-061318-114845

Microfluidic paper-based analytical devices (μPADs) are the newest generation of lab-on-a-chip devices and have made significant strides in both our understanding of fundamental behavior and performance characteristics and expansion of their applications. μPADs have become useful analytical techniques for environmental analysis in addition to their more common application as medical point-of-care devices. Although the most common method for device fabrication is wax printing, numerous other techniques exist and have helped address factors ranging from solvent compatibility to improved device function. This review highlights recent reports of fabrication and design, modes of detection, and broad applications of μPADs. Such advances have enabled μPADs to be used in field and laboratory studies to address critical needs in fast, cheaper measurement technologies.

Unraveling the KNOTTED1 regulatory network in maize meristems
Nathalie Bolduc, Alper Yılmaz, Maria Katherine Mejía‐Guerra, Kengo Morohashi +3 more
2012· Genes & Development315doi:10.1101/gad.193433.112

KNOTTED1 (KN1)-like homeobox (KNOX) transcription factors function in plant meristems, self-renewing structures consisting of stem cells and their immediate daughters. We defined the KN1 cistrome in maize inflorescences and found that KN1 binds to several thousand loci, including 643 genes that are modulated in one or multiple tissues. These KN1 direct targets are strongly enriched for transcription factors (including other homeobox genes) and genes participating in hormonal pathways, most significantly auxin, demonstrating that KN1 plays a key role in orchestrating the upper levels of a hierarchical gene regulatory network that impacts plant meristem identity and function.