Three Months of Rifapentine and Isoniazid for Latent Tuberculosis Infection

R. Sterling, Timothy; E. Villarino, Margarita; Borisov, Andrey; Shang, Nong; M. Gordin, Fred; Bliven-Sizemore, Erin; Hackman, Judith; Hamilton, Carol; Menzies, Dick; Kerrigan, Amy; E. Weis, Stephen; Weiner, Marc; Wing, Diane; Barreto Conde, Marcus; Bozeman, Lorna; Robert Horsburgh, C.; E. Chaisson, Richard

doi:10.1056/nejmoa1104875

Public

Three Months of Rifapentine and Isoniazid for Latent Tuberculosis Infection

Published in New England Journal of Medicine • Dec 7, 2011

Authors:

Timothy R. Sterling

Margarita E. Villarino

Andrey Borisov

Abstract

BACKGROUND: Treatment of latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control and elimination. The current standard regimen of isoniazid for 9 months is efficacious but is limited by toxicity and low rates of treatment completion. METHODS: We conducted an ope...

Subject

Rifapentine

Medicine

Isoniazid

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