Improved Cellular Specificity of Plasmonic Nanobubbles versus Nanoparticles in Heterogeneous Cell Systems

Y. Lukianova‐Hleb, Ekaterina; Ren, Xiaoyang; E. Constantinou, Pamela; P. Danysh, Brian; L. Shenefelt, Derek; D. Carson, Daniel; C. Farach‐Carson, Mary; A. Kulchitsky, V.; Wu, Xiangwei; S. Wagner, Daniel; O. Lapotko, Dmitri

doi:10.1371/journal.pone.0034537

Public

Improved Cellular Specificity of Plasmonic Nanobubbles versus Nanoparticles in Heterogeneous Cell Systems

Published in PLoS ONE • Apr 3, 2012

Authors:

Ekaterina Y. Lukianova‐Hleb

Xiaoyang Ren

Pamela E. Constantinou

Abstract

The limited specificity of nanoparticle (NP) uptake by target cells associated with a disease is one of the principal challenges of nanomedicine. Using the threshold mechanism of plasmonic nanobubble (PNB) generation and enhanced accumulation and clustering of gold nanoparticles in target cells, we ...

Subject

Nanomedicine

Biophysics

Cell

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