Minimizing Errors in Acute Traumatic Spinal Cord Injury Trials by Acknowledging the Heterogeneity of Spinal Cord Anatomy and Injury Severity: An Observational Canadian Cohort Analysis

F. Dvorak, Marcel; K. Noonan, Vanessa; Fallah, Nader; G. Fisher, Charles; S. Rivers, Carly; Ahn, Henry; C. Tsai, Eve; Linassi, Gary; Christie, Sean; Attabib, Najmedden; John Hurlbert, R.; R. Fourney, Daryl; G. Johnson, Michael; G. Fehlings, Michael; Drew, Brian; S. Bailey, Christopher; Paquet, Jérôme; Parent, Stefan; Townson, Andrea; Ho, Chester; Catharine Craven, B.; H. Gagnon, Dany; Tsui, Deborah; Fox, Richard; Mac‐Thiong, Jean‐Marc; K. Kwon, Brian

doi:10.1089/neu.2013.3278

Public

Minimizing Errors in Acute Traumatic Spinal Cord Injury Trials by Acknowledging the Heterogeneity of Spinal Cord Anatomy and Injury Severity: An Observational Canadian Cohort Analysis

Published in Journal of Neurotrauma • May 8, 2014

Authors:

Marcel F. Dvorak

Vanessa K. Noonan

Nader Fallah

Abstract

Clinical trials of therapies for acute traumatic spinal cord injury (tSCI) have failed to convincingly demonstrate efficacy in improving neurologic function. Failing to acknowledge the heterogeneity of these injuries and under-appreciating the impact of the most important baseline prognostic variabl...

Subject

Medicine

Spinal cord injury

Clinical trial

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