Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13-<i>cis</i>-Retinoic Acid

K. Matthay, Katherine; G. Villablanca, Judith; C. Seeger, Robert; O. Stram, Daniel; E. Harris, Richard; K.C. Ramsay, Norma; S. Swift, Patrick; Shimada, Hiroyuki; T. Black, Charles; M. Brodeur, Garrett; B. Gerbing, Robert; Patrick Reynolds, C.

doi:10.1056/nejm199910143411601

Public

Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13-cis-Retinoic Acid

Published in New England Journal of Medicine • Oct 14, 1999

Authors:

Katherine K. Matthay

Judith G. Villablanca

Robert C. Seeger

Abstract

BACKGROUND: Children with high-risk neuroblastoma have a poor outcome. In this study, we assessed whether myeloablative therapy in conjunction with transplantation of autologous bone marrow improved event-free survival as compared with chemotherapy alone, and whether subsequent treatment with 13-cis...

Subject

Medicine

Chemotherapy

Internal medicine

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