The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases

A. Cabral-Pacheco, Griselda; Garza‐Veloz, Idalia; Castruita-De la Rosa, Claudia; Manuel Ramirez-Acuña, Jesus; A Perez-Romero, Braulio; F Guerrero-Rodriguez, Jesús; Martínez-Avila, Nadia; L. Martínez‐Fierro, Margarita

doi:10.3390/ijms21249739

Public

The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases

Published in International Journal of Molecular Sciences • Dec 20, 2020

Authors:

Griselda A. Cabral-Pacheco

Idalia Garza‐Veloz

Claudia Castruita-De la Rosa

Abstract

Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM) remodeling endopeptidases that have the capacity to degrade almost every component of the ECM. The degradation of the ECM is of great importance, since it is related to embryonic development and angiogenesis. ...

Subject

Matrix metalloproteinase

Angiogenesis

Extracellular matrix

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