Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection.

Feng, Shuo; J Phillips, Daniel; White, Thomas; Sayal, Homesh; K Aley, Parvinder; Bibi, Sagida; Dold, Christina; Fuskova, Michelle; C Gilbert, Sarah; Hirsch, Ian; E Humphries, Holly; Jepson, Brett; J Kelly, Elizabeth; Plested, Emma; Shoemaker, Kathryn; M Thomas, Kelly; Vekemans, Johan; L Villafana, Tonya; Lambe, Teresa; J Pollard, Andrew; Voysey, Merryn; COVID Vaccine Trial Group, Oxford

doi:10.1038/s41591-021-01540-1

Public

Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection.

Shared by NobleBlocks on Nov 1, 2021 • 12:00 AM UTC

Authors:

Shuo Feng

Daniel J Phillips

Thomas White

Abstract

The global supply of COVID-19 vaccines remains limited. An understanding of the immune response that is predictive of protection could facilitate rapid licensure of new vaccines. Data from a randomized efficacy trial of the ChAdOx1 nCoV-19 (AZD1222) vaccine in the United Kingdom was analyzed to dete...

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