Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection

Feng, Shuo; J. Phillips, Daniel; White, Thomas; Sayal, Homesh; K. Aley, Parvinder; Bibi, Sagida; Dold, Christina; Fuskova, Michelle; C. Gilbert, Sarah; Hirsch, Ian; E. Humphries, Holly; Jepson, Brett; J. Kelly, Elizabeth; Plested, Emma; Shoemaker, Kathryn; Thomas, Kelly; Vekemans, Johan; Villafana, Tonya; Lambe, Teresa; J. Pollard, Andrew; Voysey, Merryn; Oxford COVID Vaccine Trial Group, the; Adlou, Syed; Allen, Lauren; Angus, Brian; Anslow, Rachel; Asselin, Marie‐Claude; Baker, Natalie; Baker, Philip; Barlow, Thomas; Beveridge, Amy; R. Bewley, Kevin; J. Brown, Phillip; Brunt, Emily; R. Buttigieg, Karen; Camara, Susana; Charlton, Sue; Chiplin, Emily; Cicconi, Paola; Clutterbuck, Elizabeth; M. Collins, Andrea; S. Coombes, Naomi; Ann Costa Clemens, Sue; Davison, M.; Demissie, Tesfaye; Dinesh, Tanya; D. Douglas, Alexander; Duncan, C.J.; R. W. Emary, Katherine; Ewer, Katie; Felle, Sally; M. Ferreira, Daniela; Finn, Adam; M. Folegatti, Pedro; Fothergill, Ross; Fraser, Sara; Garlant, Harriet; Gatcombe, Laura; Godwin, Kerry; L. Goodman, Anna; Green, Christopher; Hallis, Bassam; C. Hart, Thomas; T. Heath, Paul; Hill, Helen; V. S. Hill, Adrian; Jenkin, Daniel; Kasanyinga, Mwila; Kerridge, Simon; Knight, Chanice; Leung, Stephanie; Libri, Vincenzo; Lillie, Patrick; Marinou, Spyridoula; McGlashan, Joanna; McGregor, Alastair; McInroy, Lorna; M. Minassian, Angela; F Mujadidi, Yama; J. Penn, Elizabeth; J. Petropoulos, Christos; M. Pollock, Katrina; C. Proud, Pamela; Provstgaard-Morys, Samuel; Rajapaska, Durga; Ramasamy, Maheshi; Sanders, Katherine; H. Shaik, Imam; Singh, Nisha; Smith, Andrew; D. Snape, Matthew; Song, Rinn; Shrestha, Sonu; Sutherland, Rebecca; C. Thomson, Emma; P. J. Turner, David; Webb-Bridges, Alice; Wrin, Terri; J. Williams, Christopher

doi:10.1038/s41591-021-01540-1

Public

Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection

Published in Nature Medicine • Sep 29, 2021

Authors:

Shuo Feng

Daniel J. Phillips

Thomas White

Abstract

Abstract The global supply of COVID-19 vaccines remains limited. An understanding of the immune response that is predictive of protection could facilitate rapid licensure of new vaccines. Data from a randomized efficacy trial of the ChAdOx1 nCoV-19 (AZD1222) vaccine in the United Kingdom was analyze...

Subject

Asymptomatic

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Coronavirus disease 2019 (COVID-19)

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