Antibody-Drug Conjugates: A Comprehensive Review.
Published in Molecular cancer research : MCR • Jan 1, 2020
Authors:,,
Puregmaa Khongorzul
Cai Jia Ling
Farhan Ullah Khan
Abstract
Antibody-drug conjugates (ADC) are one of the fastest growing anticancer drugs. This approach comprises a mAb conjugated to the cytotoxic payload via a chemical linker that directed toward a target antigen expressed on the cancer cell surface, reducing systemic exposure and therefore toxicity. ADCs ...
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