Universidad de Los Andes

Introduction Recent decades have seen a major international effort to inventory tree communities in the Amazon Basin and Guiana Shield (Amazonia), but the vast extent and record diversity of these forests have hampered an understanding of basinwide patterns. To overcome this obstacle, we compiled and standardized species-level data on more than half a million trees in 1170 plots sampling all major lowland forest types to explore patterns of commonness, rarity, and richness. Methods The ~6-million-km 2 Amazonian lowlands were divided into 1° cells, and mean tree density was estimated for each cell by using a loess regression model that included no environmental data but had its basis exclusively in the geographic location of tree plots. A similar model, allied with a bootstrapping exercise to quantify sampling error, was used to generate estimated Amazon-wide abundances of the 4962 valid species in the data set. We estimated the total number of tree species in the Amazon by fitting the mean rank-abundance data to Fisher’s log-series distribution. Results Our analyses suggest that lowland Amazonia harbors 3.9 × 10 11 trees and ~16,000 tree species. We found 227 “hyperdominant” species (1.4% of the total) to be so common that together they account for half of all trees in Amazonia, whereas the rarest 11,000 species account for just 0.12% of trees. Most hyperdominants are habitat specialists that have large geographic ranges but are only dominant in one or two regions of the basin, and a median of 41% of trees in individual plots belong to hyperdominants. A disproportionate number of hyperdominants are palms, Myristicaceae, and Lecythidaceae. Discussion The finding that Amazonia is dominated by just 227 tree species implies that most biogeochemical cycling in the world’s largest tropical forest is performed by a tiny sliver of its diversity. The causes underlying hyperdominance in these species remain unknown. Both competitive superiority and widespread pre-1492 cultivation by humans are compelling hypotheses that deserve testing. Although the data suggest that spatial models can effectively forecast tree community composition and structure of unstudied sites in Amazonia, incorporating environmental data may yield substantial improvements. An appreciation of how thoroughly common species dominate the basin has the potential to simplify research in Amazonian biogeochemistry, ecology, and vegetation mapping. Such advances are urgently needed in light of the >10,000 rare, poorly known, and potentially threatened tree species in the Amazon.

Large-scale societies in which strangers regularly engage in mutually beneficial transactions are puzzling. The evolutionary mechanisms associated with kinship and reciprocity, which underpin much of primate sociality, do not readily extend to large unrelated groups. Theory suggests that the evolution of such societies may have required norms and institutions that sustain fairness in ephemeral exchanges. If that is true, then engagement in larger-scale institutions, such as markets and world religions, should be associated with greater fairness, and larger communities should punish unfairness more. Using three behavioral experiments administered across 15 diverse populations, we show that market integration (measured as the percentage of purchased calories) positively covaries with fairness while community size positively covaries with punishment. Participation in a world religion is associated with fairness, although not across all measures. These results suggest that modern prosociality is not solely the product of an innate psychology, but also reflects norms and institutions that have emerged over the course of human history.

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BACKGROUND: The role of trypanocidal therapy in patients with established Chagas' cardiomyopathy is unproven. METHODS: We conducted a prospective, multicenter, randomized study involving 2854 patients with Chagas' cardiomyopathy who received benznidazole or placebo for up to 80 days and were followed for a mean of 5.4 years. The primary outcome in the time-to-event analysis was the first event of any of the components of the composite outcome of death, resuscitated cardiac arrest, sustained ventricular tachycardia, insertion of a pacemaker or implantable cardioverter-defibrillator, cardiac transplantation, new heart failure, stroke, or other thromboembolic event. RESULTS: The primary outcome occurred in 394 patients (27.5%) in the benznidazole group and in 414 (29.1%) in the placebo group (hazard ratio, 0.93; 95% confidence interval [CI], 0.81 to 1.07; P=0.31). At baseline, a polymerase-chain-reaction (PCR) assay was performed on blood samples obtained from 1896 patients; 60.5% had positive results for Trypanosoma cruzi on PCR. The rates of conversion to negative PCR results (PCR conversion) were 66.2% in the benznidazole group and 33.5% in the placebo group at the end of treatment, 55.4% and 35.3%, respectively, at 2 years, and 46.7% and 33.1%, respectively, at 5 years or more (P<0.001 for all comparisons). The effect of treatment on PCR conversion varied according to geographic region: in Brazil, the odds ratio for PCR conversion was 3.03 (95% CI, 2.12 to 4.34) at 2 years and 1.87 (95% CI, 1.33 to 2.63) at 5 or more years; in Colombia and El Salvador, the odds ratio was 1.33 (95% CI, 0.90 to 1.98) at 2 years and 0.96 (95% CI, 0.63 to 1.45) at 5 or more years; and in Argentina and Bolivia, the odds ratio was 2.63 (95% CI, 1.89 to 3.66) at 2 years and 2.79 (95% CI, 1.99 to 3.92) at 5 or more years (P<0.001 for interaction). However, the rates of PCR conversion did not correspond to effects on clinical outcome (P=0.16 for interaction). CONCLUSIONS: Trypanocidal therapy with benznidazole in patients with established Chagas' cardiomyopathy significantly reduced serum parasite detection but did not significantly reduce cardiac clinical deterioration through 5 years of follow-up. (Funded by the Population Health Research Institute and others; ClinicalTrials.gov number, NCT00123916; Current Controlled Trials number, ISRCTN13967269.).

Markus and Kitayama's (1991) theory of independent and interdependent self-construals had a major influence on social, personality, and developmental psychology by highlighting the role of culture in psychological processes. However, research has relied excessively on contrasts between North American and East Asian samples, and commonly used self-report measures of independence and interdependence frequently fail to show predicted cultural differences. We revisited the conceptualization and measurement of independent and interdependent self-construals in 2 large-scale multinational surveys, using improved methods for cross-cultural research. We developed (Study 1: N = 2924 students in 16 nations) and validated across cultures (Study 2: N = 7279 adults from 55 cultural groups in 33 nations) a new 7-dimensional model of self-reported ways of being independent or interdependent. Patterns of global variation support some of Markus and Kitayama's predictions, but a simple contrast between independence and interdependence does not adequately capture the diverse models of selfhood that prevail in different world regions. Cultural groups emphasize different ways of being both independent and interdependent, depending on individualism-collectivism, national socioeconomic development, and religious heritage. Our 7-dimensional model will allow future researchers to test more accurately the implications of cultural models of selfhood for psychological processes in diverse ecocultural contexts. (PsycINFO Database Record

We introduce Ego4D, a massive-scale egocentric video dataset and benchmark suite. It offers 3,670 hours of dailylife activity video spanning hundreds of scenarios (household, outdoor, workplace, leisure, etc.) captured by 931 unique camera wearers from 74 worldwide locations and 9 different countries. The approach to collection is designed to uphold rigorous privacy and ethics standards, with consenting participants and robust de-identification procedures where relevant. Ego4D dramatically expands the volume of diverse egocentric video footage publicly available to the research community. Portions of the video are accompanied by audio, 3D meshes of the environment, eye gaze, stereo, and/or synchronized videos from multiple egocentric cameras at the same event. Furthermore, we present a host of new benchmark challenges centered around understanding the first-person visual experience in the past (querying an episodic memory), present (analyzing hand-object manipulation, audio-visual conversation, and social interactions), and future (forecasting activities). By publicly sharing this massive annotated dataset and benchmark suite, we aim to push the frontier of first-person perception. Project page: https://ego4d-data.org/

This article charts the promissory notes and concerns related to college-level online education as reflected in the educational literature. It is argued that, to appreciate the potential and limitations of online education, we need to trace the issues that bind online education with distance education. The article reviews the history of distance education through the lenses of three historical themes—democratization, liberal education, and educational quality—and charts the current scene of online education in terms of three educational visions that may inform the development of online initiatives: the presentational view, the performance-tutoring view, and the epistemic-engagement view. The article emphasizes the potential contributions of online education to democratization and the advancement of the scholarship of teaching.

Importance: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. Objective: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion. Evidence Review: Cause-specific mortality and nonfatal health outcomes were analyzed for 195 countries and territories by age group, sex, and year from 1990 to 2015 using standardized approaches for data processing and statistical modeling, with subsequent analysis of the findings to describe levels and trends across geography and time among children and adolescents 19 years or younger. A composite indicator of income, education, and fertility was developed (Socio-demographic Index [SDI]) for each geographic unit and year, which evaluates the historical association between SDI and health loss. Findings: Global child and adolescent mortality decreased from 14.18 million (95% uncertainty interval [UI], 14.09 million to 14.28 million) deaths in 1990 to 7.26 million (95% UI, 7.14 million to 7.39 million) deaths in 2015, but progress has been unevenly distributed. Countries with a lower SDI had a larger proportion of mortality burden (75%) in 2015 than was the case in 1990 (61%). Most deaths in 2015 occurred in South Asia and sub-Saharan Africa. Global trends were driven by reductions in mortality owing to infectious, nutritional, and neonatal disorders, which in the aggregate led to a relative increase in the importance of noncommunicable diseases and injuries in explaining global disease burden. The absolute burden of disability in children and adolescents increased 4.3% (95% UI, 3.1%-5.6%) from 1990 to 2015, with much of the increase owing to population growth and improved survival for children and adolescents to older ages. Other than infectious conditions, many top causes of disability are associated with long-term sequelae of conditions present at birth (eg, neonatal disorders, congenital birth defects, and hemoglobinopathies) and complications of a variety of infections and nutritional deficiencies. Anemia, developmental intellectual disability, hearing loss, epilepsy, and vision loss are important contributors to childhood disability that can arise from multiple causes. Maternal and reproductive health remains a key cause of disease burden in adolescent females, especially in lower-SDI countries. In low-SDI countries, mortality is the primary driver of health loss for children and adolescents, whereas disability predominates in higher-SDI locations; the specific pattern of epidemiological transition varies across diseases and injuries. Conclusions and Relevance: Consistent international attention and investment have led to sustained improvements in causes of health loss among children and adolescents in many countries, although progress has been uneven. The persistence of infectious diseases in some countries, coupled with ongoing epidemiologic transition to injuries and noncommunicable diseases, require all countries to carefully evaluate and implement appropriate strategies to maximize the health of their children and adolescents and for the international community to carefully consider which elements of child and adolescent health should be monitored.

A metric structure is a many-sorted structure with each sort a metric space, which for convenience is assumed to have finite diameter. Additionally there are functions (of several variables) between sorts, assumed to be uniformly continuous. Examples include metric spaces themselves, measure algebras (with the metric d(A, B) = µ(A∆B), where ∆ is symmetric difference), and structures based on Banach spaces (where one interprets the sorts as balls), including Banach lattices, C*algebras, etc. The usual first-order logic does not work very well for such structures, and several good alternatives have been developed. One is the logic of positive bounded formulas with an approximate semantics (see [3]). Another is the setting of compact abstract theories (cats) (see [1]). A recent development, which will be emphasized in this course, is the convergence of these two points of view and the realization that they are also connected to the [0,1]-valued continuous logic that was studied extensively in the 1960s and then dropped (see [2]). This leads to a new formalism for the logic of metric structures in which the operations of sup and inf play a central role. The analogy between this logic for metric space structures and the usual first order logic for ordinary structures is far reaching. This new logic satisfies the compactness theorem, Löwenheim-Skolem

We present baryon acoustic oscillation (BAO) measurements from more than 14 million galaxies and quasars drawn from the Dark Energy Spectroscopic Instrument (DESI) Data Release 2 (DR2), based on three years of operation. For cosmology inference, these galaxy measurements are combined with DESI Lyman- <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" display="inline"> <a:mi>α</a:mi> </a:math> forest BAO results presented in a companion paper (M. Abdul-Karim , companion paper, .). The DR2 BAO results are consistent with DESI DR1 and the Sloan Digital Sky Survey, and their distance-redshift relationship matches those from recent compilations of supernovae (SNe) over the same redshift range. The results are well described by a flat <c:math xmlns:c="http://www.w3.org/1998/Math/MathML" display="inline"> <c:mi mathvariant="normal">Λ</c:mi> </c:math> cold dark matter ( <f:math xmlns:f="http://www.w3.org/1998/Math/MathML" display="inline"> <f:mi mathvariant="normal">Λ</f:mi> <f:mi>CDM</f:mi> </f:math> ) model, but the parameters preferred by BAO are in mild, <i:math xmlns:i="http://www.w3.org/1998/Math/MathML" display="inline"> <i:mn>2.3</i:mn> <i:mi>σ</i:mi> </i:math> tension with those determined from the cosmic microwave background (CMB), although the DESI results are consistent with the acoustic angular scale <k:math xmlns:k="http://www.w3.org/1998/Math/MathML" display="inline"> <k:msub> <k:mi>θ</k:mi> <k:mo>*</k:mo> </k:msub> </k:math> that is well measured by Planck. This tension is alleviated by dark energy with a time-evolving equation of state parametrized by <m:math xmlns:m="http://www.w3.org/1998/Math/MathML" display="inline"> <m:msub> <m:mi>w</m:mi> <m:mn>0</m:mn> </m:msub> </m:math> and <o:math xmlns:o="http://www.w3.org/1998/Math/MathML" display="inline"> <o:msub> <o:mi>w</o:mi> <o:mi>a</o:mi> </o:msub> </o:math> , which provides a better fit to the data, with a favored solution in the quadrant with <q:math xmlns:q="http://www.w3.org/1998/Math/MathML" display="inline"> <q:msub> <q:mi>w</q:mi> <q:mn>0</q:mn> </q:msub> <q:mo>&gt;</q:mo> <q:mo>−</q:mo> <q:mn>1</q:mn> </q:math> and <s:math xmlns:s="http://www.w3.org/1998/Math/MathML" display="inline"> <s:msub> <s:mi>w</s:mi> <s:mi>a</s:mi> </s:msub> <s:mo>&lt;</s:mo> <s:mn>0</s:mn> </s:math> . This solution is preferred over <u:math xmlns:u="http://www.w3.org/1998/Math/MathML" display="inline"> <u:mi mathvariant="normal">Λ</u:mi> <u:mi>CDM</u:mi> </u:math> at <x:math xmlns:x="http://www.w3.org/1998/Math/MathML" display="inline"> <x:mn>3.1</x:mn> <x:mi>σ</x:mi> </x:math> for the combination of DESI BAO and CMB data. When also including SNe, the preference for a dynamical dark energy model over <z:math xmlns:z="http://www.w3.org/1998/Math/MathML" display="inline"> <z:mi mathvariant="normal">Λ</z:mi> <z:mi>CDM</z:mi> </z:math> ranges from <cb:math xmlns:cb="http://www.w3.org/1998/Math/MathML" display="inline"> <cb:mn>2.8</cb:mn> <cb:mo>−</cb:mo> <cb:mn>4.2</cb:mn> <cb:mi>σ</cb:mi> </cb:math> depending on which SNe sample is used. We present evidence from other data combinations which also favor the same behavior at high significance. From the combination of DESI and CMB we derive 95% upper limits on the sum of neutrino masses, finding <eb:math xmlns:eb="http://www.w3.org/1998/Math/MathML" display="inline"> <eb:mo>∑</eb:mo> <eb:msub> <eb:mi>m</eb:mi> <eb:mi>ν</eb:mi> </eb:msub> <eb:mo>&lt;</eb:mo> <eb:mn>0.064</eb:mn> <eb:mtext> </eb:mtext> <eb:mtext> </eb:mtext> <eb:mi>eV</eb:mi> </eb:math> assuming <gb:math xmlns:gb="http://www.w3.org/1998/Math/MathML" display="inline"> <gb:mi mathvariant="normal">Λ</gb:mi> <gb:mi>CDM</gb:mi> </gb:math> and <jb:math xmlns:jb="http://www.w3.org/1998/Math/MathML" display="inline"> <jb:mo>∑</jb:mo> <jb:msub> <jb:mi>m</jb:mi> <jb:mi>ν</jb:mi> </jb:msub> <jb:mo>&lt;</jb:mo> <jb:mn>0.16</jb:mn> <jb:mtext> </jb:mtext> <jb:mtext> </jb:mtext> <jb:mi>eV</jb:mi> </jb:math> in the <lb:math xmlns:lb="http://www.w3.org/1998/Math/MathML" display="inline"> <lb:msub> <lb:mi>w</lb:mi> <lb:mn>0</lb:mn> </lb:msub> <lb:msub> <lb:mi>w</lb:mi> <lb:mi>a</lb:mi> </lb:msub> </lb:math> model. Unless there is an unknown systematic error associated with one or more datasets, it is clear that <nb:math xmlns:nb="http://www.w3.org/1998/Math/MathML" display="inline"> <nb:mi mathvariant="normal">Λ</nb:mi> <nb:mi>CDM</nb:mi> </nb:math> is being challenged by the combination of DESI BAO with other measurements and that dynamical dark energy offers a possible solution.

Computational thinking (CT) uses concepts that are essential to computing and information science to solve problems, design and evaluate complex systems, and understand human reasoning and behavior. This way of thinking has important implications in computer sciences as well as in almost every other field. Therefore, we contend that CT should be taught in elementary schools and included in every university’s educational curriculum. Several studies that measure the impact of teaching programming, analytical thinking, and CT have been conducted. In this review, we analyze and discuss findings from these studies and highlight the importance of learning programming with a focus on the development of CT skills at a young age. We also describe the tools that are available to improve the teaching of CT and provide a state-of-the-art overview of how programming is being taught at schools and universities in Colombia and around the world.

La contingencia provocada por la pandemia de la covid-19 (del inglés, coronavirus disease 2019) ha generado una situación inédita en los escenarios de la educación superior en México y en el mundo. Este documento reporta los resultados de una encuesta aplicada en línea a profesores de bachillerato, licenciatura y posgrado de la Universidad Nacional Autónoma de México (unam) el 25 de marzo de 2020. De una muestra de 788 docentes de la unam, respondieron 383 (48.6%), de los cuales 60.5% están de acuerdo con el apoyo institucional que han recibido de la Universidad durante la contingencia. Las principales problemáticas a las que se enfrentan son logísticas (43.3%), tecnológicas (39.7%), pedagógicas (35.2%) y socioafectivas (14.9%). En cuanto al uso de la tecnología, para comunicación usan principalmente el correo electrónico, Facebook y WhatsApp; para trabajo académico, Google Classroom, Moodle y Google Suite; y para trabajo sincrónico, Zoom, Google Hangouts y Skype. En su mayoría, refieren requerir apoyo tecnológico y asesoría didáctica. A la pregunta abierta acerca de las propuestas que solicitan, en orden de importancia éstas son: formación pedagógica, disponibilidad de recursos digitales, recursos informativos sobre uso de tecnologías en educación, mejora de procesos institucionales, acompañamiento pedagógico, asesoría técnica e información de los recursos institucionales.

Civil wars and ethnic conflicts have resulted in an estimated number of approximately 35 million refugees and internally displaced persons worldwide. Understanding the determinants of forced migration is an important prerequisite for the definition of appropriate policies of prevention, assistance, and relocation. We develop a conceptual framework for the empirical analysis of displacement decisions at the household level. While similarities to conventional migration theories exist, there are also important differences implied by the presence of violent conflict. For example, risk aversion and lack of information may hamper conventional migration but enhance displacement. Factors such as landholdings and social capital at the place of origin may not only reduce displacement in the conventional sense of raising opportunity costs but may also spur displacement indirectly by increasing the household’s likelihood of becoming the victim of direct threats. For the case of Colombia, we conduct an econometric analysis of the determinants of displacement and of direct threats. We conclude with policy recommendations and directions for further research.

BACKGROUND: We compared 24-hour waist-worn accelerometer wear time characteristics of 9-11 year old children in the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) to similarly aged U.S. children providing waking-hours waist-worn accelerometer data in the 2003-2006 National Health and Nutrition Examination Survey (NHANES). METHODS: Valid cases were defined as having ≥4 days with ≥10 hours of waking wear time in a 24-hour period, including one weekend day. Previously published algorithms for extracting total sleep episode time from 24-hour accelerometer data and for identifying wear time (in both the 24-hour and waking-hours protocols) were applied. The number of valid days obtained and a ratio (percent) of valid cases to the number of participants originally wearing an accelerometer were computed for both ISCOLE and NHANES. Given the two surveys' discrepant sampling designs, wear time (minutes/day, hours/day) from U.S. ISCOLE was compared to NHANES using a meta-analytic approach. Wear time for the 11 additional countries participating in ISCOLE were graphically compared with NHANES. RESULTS: 491 U.S. ISCOLE children (9.92±0.03 years of age [M±SE]) and 586 NHANES children (10.43 ± 0.04 years of age) were deemed valid cases. The ratio of valid cases to the number of participants originally wearing an accelerometer was 76.7% in U.S. ISCOLE and 62.6% in NHANES. Wear time averaged 1357.0 ± 4.2 minutes per 24-hour day in ISCOLE. Waking wear time was 884.4 ± 2.2 minutes/day for U.S. ISCOLE children and 822.6 ± 4.3 minutes/day in NHANES children (difference = 61.8 minutes/day, p < 0.001). Wear time characteristics were consistently higher in all ISCOLE study sites compared to the NHANES protocol. CONCLUSIONS: A 24-hour waist-worn accelerometry protocol implemented in U.S. children produced 22.6 out of 24 hours of possible wear time, and 61.8 more minutes/day of waking wear time than a similarly implemented and processed waking wear time waist-worn accelerometry protocol. Consistent results were obtained internationally. The 24-hour protocol may produce an important increase in wear time compliance that also provides an opportunity to study the total sleep episode time separate and distinct from physical activity and sedentary time detected during waking-hours. TRIAL REGISTRATION: ClinicalTrials.gov NCT01722500 .

Estimates of extinction risk for Amazonian plant and animal species are rare and not often incorporated into land-use policy and conservation planning. We overlay spatial distribution models with historical and projected deforestation to show that at least 36% and up to 57% of all Amazonian tree species are likely to qualify as globally threatened under International Union for Conservation of Nature (IUCN) Red List criteria. If confirmed, these results would increase the number of threatened plant species on Earth by 22%. We show that the trends observed in Amazonia apply to trees throughout the tropics, and we predict that most of the world's >40,000 tropical tree species now qualify as globally threatened. A gap analysis suggests that existing Amazonian protected areas and indigenous territories will protect viable populations of most threatened species if these areas suffer no further degradation, highlighting the key roles that protected areas, indigenous peoples, and improved governance can play in preventing large-scale extinctions in the tropics in this century.

Abstract Many formulations used in surfactant flooding involve blends of surfactants designed to glue the best oil-recovery efficiency. Because oil-recovery efficiency usually is presumed to relate closely to surfactant/brine/oil phase behavior, it is of interest to understand the effect of mixing surfactants or of mixing oils on this phase behavior.We show that a correlation defining optimal behavior as a function of salinity, alcohol type and concentration, temperature, WOR (water/oil ratio), and oil type can be extended to mixtures of sulfonated surfactants and to those of sulfonates with sulfates and of sulfonates with alkanoates, provided the proper mixing rules are observed. provided the proper mixing rules are observed. The mixing rules apply to some mixtures of anionic and nonionic surfactants, but not to all. These mixtures exhibit some properties that may be of practical interest, such as increased salinity and practical interest, such as increased salinity and temperature tolerance. Introduction Recent studies have shown that formulation of the surfactant/brine/oil system is a key factor governing the performance of microemulsions designed to recover residual oil. These studies demonstrate that all optimal formulations exhibit characteristic properties that are remarkably similar. In general, properties that are remarkably similar. In general, the optimal microemulsion can solubilize large quantities of oil and connate water; in the presence of excess quantities of oil and water, a third surfactant-rich middle phase is formed. The interfacial tensions (IFT's) between the excess phases and the surfactant-rich phase are both low - about 10 dyne/cm (10 mN/m). Given an oil/brine system from a particular reservoir, one can achieve this formulation by varying the surfactant or the cosurfactant. Different oils, brines, or temperatures require formulations correspondingly altered to maintain optimal conditions. Previous studies have shown that the three-phase region exists over a range of values when one parameter, such as cosurfactant concentration, parameter, such as cosurfactant concentration, salinity, temperature, etc., is varied systematically (often called a scan). Thus, some ambiguity may exist with regard to the selection of those parameters representing the optimal formulation. Clearly, the optimum is that which recovers the most oil. However, tests are laborious, difficult to reproduce precisely, and sensitive to other factors, such as precisely, and sensitive to other factors, such as mobility, surfactant retention, wettability, etc. Therefore, it is desirable to impose an alternative definition that can be used for screening, though the final design still is dictated by core floods.Healy and Reeds have shown that the optimal formulation for oil recovery closely corresponds to that for which the IFT's between the excess oil and water phases and the surfactant-rich phase are equal. An almost equivalent criterion also was shown to be that point in the three-phase region for which the volume of oil solubilized into the middle phase equals the volume of brine. Furthermore, Salager et al. have used still another criterion that seems to be essentially equivalent to those used by Healy and Reed - an optimal salinity is defined as the midpoint of the salinity range for which the system exhibits three phases.These criteria are useful because they permit the screening of microemulsion systems using simple laboratory tests. SPEJ P. 271

Eco-certification of food and other agricultural products has been promoted as a way of making markets work for sustainability. Certification programs offer a price premium to producers who invest in more sustainable practices. The literature on the impacts of certification has focused primarily on the economic benefits farmers perceive from participating in these schemes. These benefits, however, are often subject to price variability, offering only a partial explanation of why farmers join and stay in certification programs. We evaluated the potential of the Rainforest Alliance certification program to foster more resilient social-ecological systems in the face of globalization. Using the case of Santander, Colombia, and a pair-based comparison of 86 households to effectively produce a robust counterfactual, we showed that certification provides important environmental benefits, while improving the well-being of farmers and their communities. Furthermore, the study showed that price premiums are only one of many elements defining the success of certification, particularly important for motivating farmers to join, but less so to explain retention and upgrading. The case of Colombian coffee growers illustrates how the connections between local social-ecological systems and larger global forces can produce more sustainable livelihoods and land uses.

We aim to detect all instances of a category in an image and, for each instance, mark the pixels that belong to it. We call this task Simultaneous Detection and Segmentation (SDS). Unlike classical bounding box detection, SDS requires a segmentation and not just a box. Unlike classical semantic segmentation, we require individual object instances. We build on recent work that uses convolutional neural networks to classify category-independent region proposals (R-CNN [16]), introducing a novel architecture tailored for SDS. We then use category-specific, top- down figure-ground predictions to refine our bottom-up proposals. We show a 7 point boost (16% relative) over our baselines on SDS, a 5 point boost (10% relative) over state-of-the-art on semantic segmentation, and state-of-the-art performance in object detection. Finally, we provide diagnostic tools that unpack performance and provide directions for future work.

Macrophages are essential for appendage regeneration after amputation in regenerative species. The molecular mechanisms through which macrophages orchestrate blastema formation and regeneration are still unclear. Here, we use the genetically tractable and transparent zebrafish larvae to study the functions of polarized macrophage subsets during caudal fin regeneration. After caudal fin amputation, we show an early and transient accumulation of pro-inflammatory macrophages concomitant with the accumulation of non-inflammatory macrophages which, in contrast to pro-inflammatory macrophages, remain associated to the fin until the end of the regeneration. Chemical and genetic depletion of macrophages suggested that early recruited macrophages that express TNFα are critical for blastema formation. Combining parabiosis and morpholino knockdown strategies, we show that TNFα/TNFR1 signaling pathway is required for the fin regeneration. Our study reveals that TNFR1 has a necessary and direct role in blastema cell activation suggesting that macrophage subset balance provides the accurate TNFα signal to prime regeneration in zebrafish.

Abstract This paper surveys recent literature, both theoretical and empirical, regarding political explanations for fiscal deficits. Political economy suggests conflicts of interest may lie behind the emergence of deficits: (1) Opportunistic politicians generate deficits to win elections, even in conflict with general welfare; (2) Conflicts of interests between politicians’ partisan preferences create incentives for (at least some) incumbents to run deficits and (3) Conflicts of interest between different social groups or regions generate tensions in the allocation of government resources leading to overspending. This paper reviews these different strands of the literature. It also covers contributions that highlight the crucial role of budget institutions in determining the extent to which the political motivations to generate deficits are indeed translated into poor fiscal outcomes. Promising avenues for future research are highlighted.