Carcinogenicity, DNA adduct formation and K-ras activation by 7H-dibenzo[c,g]carbazole in strain A/J mouse lung.

D, Warshawsky; G, Talaska; M, Jaeger; T, Collins; A, Galati; L, You; G, Stoner

doi:10.1093/carcin/17.4.865

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Carcinogenicity, DNA adduct formation and K-ras activation by 7H-dibenzo[c,g]carbazole in strain A/J mouse lung.

Shared by NobleBlocks on Apr 1, 1996 • 12:00 AM UTC

Authors:

Warshawsky D

Talaska G

Jaeger M

Abstract

N-Heterocyclic polynuclear aromatic hydrocarbons (NHA) are environmental pollutants formed during the combustion of organic materials. 7-H-Dibenzo[c,g]carbazole (DBC) is a potent carcinogen in lung, liver and skin. We undertook these studies to determine whether tissue specificity for DBC lung carci...

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