Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

Rezeki Hadinegoro, Sri; Luis Arredondo-Garcı́a, José; Rosario Capeding, Maria; Deseda, Carmen; Chotpitayasunondh, Tawee; Dietze, Reynaldo; Hj Muhammad Ismail, H.I.; Reynales, Humberto; Limkittikul, Kriengsak; Maribel Rivera-Medina, Doris; Ngoc Tran, Huu; Bouckenooghe, Alain; Chansinghakul, Danaya; Cortés, Margarita; Fanouillere, Karen; Forrat, Rémi; Frago, Carina; Gailhardou, Sophia; Jackson, Nicholas; Noriega, Fernando; Plennevaux, Eric; Anh Wartel, T.; Zambrano, Betzana; Saville, Mélanie

doi:10.1056/nejmoa1506223

Public

Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

Published in New England Journal of Medicine • Jul 27, 2015

Authors:

Sri Rezeki Hadinegoro

José Luis Arredondo-Garcı́a

Maria Rosario Capeding

Abstract

BACKGROUND: A candidate tetravalent dengue vaccine is being assessed in three clinical trials involving more than 35,000 children between the ages of 2 and 16 years in Asian-Pacific and Latin American countries. We report the results of long-term follow-up interim analyses and integrated efficacy an...

Subject

Medicine

Dengue fever

Dengue vaccine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!