Preliminary Report of a Multicenter Prospective Phase II Study of DA-EPOCH-R in MYC-Rearranged Aggressive B-Cell Lymphoma

Dunleavy, Kieron; A. Fanale, Michelle; S. LaCasce, Ann; Noy, Ariela; F. Caimi, Paolo; Parekh, Samir; W. Hayslip, John; Jagadeesh, Deepa; S. Lord, Raymond; Jo Lechowicz, Mary; Gaur, Rakesh; N. Lucas, Andrea; M. Staudt, Louis; M. Steinberg, Seth; S. Kahl, Brad; W. Friedberg, Jonathan; F. Little, Richard; L. Bartlett, Nancy; H. Wilson, Wyndham

doi:10.1182/blood.v124.21.395.395

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Preliminary Report of a Multicenter Prospective Phase II Study of DA-EPOCH-R in MYC-Rearranged Aggressive B-Cell Lymphoma

Shared by NobleBlocks on Dec 6, 2014 • 12:00 AM UTC

Authors:

Kieron Dunleavy

Michelle A. Fanale

Ann S. LaCasce

Abstract

Abstract Background: In diffuse large B-cell lymphoma (DLBCL), a MYC-rearrangement (MYC-R) is present in approximately 10% of cases and has been associated with an inferior outcome following R-CHOP chemotherapy. In a previous report that retrospectively analyzed the prognostic impact of a MYC-R on s...

Subject

Lymphoma

Internal medicine

Epoch (astronomy)

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