Human Mesenchymal Stem Cell Microvesicles for Treatment of <i>Escherichia coli</i> Endotoxin-Induced Acute Lung Injury in Mice

Zhu, Yinggang; Feng, Xiaomei; Abbott, Jason; Fang, Xiaohui; Qi, Hao; Monsel, Antoine; Qu, Jieming; A. Matthay, Michael; Woo Lee, Jae

doi:10.1002/stem.1504

Public

Human Mesenchymal Stem Cell Microvesicles for Treatment of Escherichia coli Endotoxin-Induced Acute Lung Injury in Mice

Published in Stem Cells • Aug 13, 2013

Authors:

Yinggang Zhu

Xiaomei Feng

Jason Abbott

Abstract

We previously found that human mesenchymal stem cells (MSC) or its conditioned medium restored lung protein permeability and reduced alveolar inflammation following Escherichia coli endotoxin-induced acute lung injury (ALI) in an ex vivo perfused human lung in part through the secretion of soluble f...

Subject

Biology

Mesenchymal stem cell

Escherichia coli

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