<i>BRCA1</i> and <i>BRCA2</i> mutations account for a large proportion of ovarian carcinoma cases

Pal, Tuya; Permuth‐Wey, Jenny; A. Betts, Judith; P. Krischer, Jeffrey; V. Fiorica, James; Arango, Hector; P. LaPolla, James; Hoffman, Mitchell; A Martino, Martin; Wakeley, Katie; D. Wilbanks, George; V. Nicosia, Santo; Cantor, Alan; Sutphen, Rebecca

doi:10.1002/cncr.21536

Public

BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases

Published in Cancer • Nov 14, 2005

Authors:

Tuya Pal

Jenny Permuth‐Wey

Judith A. Betts

Abstract

BACKGROUND: It is believed that BRCA1 and BRCA2 germline mutations account for the majority of hereditary ovarian carcinomas; however, to the authors' knowledge, there are scant data on the prevalence and spectrum of mutations, genotype/phenotype correlations, tumor histology, and family history cha...

Subject

Ovarian cancer

Medicine

Ovarian carcinoma

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