Effects of lithium and valproate on amphetamineinduced oxidative stress generation in an animal model of mania

N. Frey, Benício; S. Valvassori, Samira; Z. Réus, Gislaine; R. Martins, Márcio; Petronilho, Fabrícia; Bardini, Katrine; Dal‐Pizzol, Felipe; Kapczinski, Flávio; Quevedo, João

doi:10.1139/jpn.0637

Public

Effects of lithium and valproate on amphetamineinduced oxidative stress generation in an animal model of mania

Published in Journal of Psychiatry and Neuroscience • Sep 1, 2006

Authors:

Benício N. Frey

Samira S. Valvassori

Gislaine Z. Réus

Abstract

OBJECTIVE: Previous studies have suggested that oxidative stress may play a role in the pathophysiology of bipolar disorder (BD). Moreover, recent studies indicate that lithium and valproate exert neuroprotective effects against oxidative stress. We studied the effects of the mood stabilizers lithiu...

Subject

Mania

Lithium (medication)

Oxidative stress

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