Suppression of TNF-α-Induced Apoptosis by NF-κB

J. Van Antwerp, Daniel; J. Martin, Seamus; Kafri, Tal; R. Green, Douglas; M. Verma, Inder

doi:10.1126/science.274.5288.787

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Suppression of TNF-α-Induced Apoptosis by NF-κB

Shared by NobleBlocks on Nov 1, 1996 • 12:00 AM UTC

Authors:

Daniel J. Van Antwerp

Seamus J. Martin

Tal Kafri

Abstract

Tumor necrosis factor α (TNF-α) signaling gives rise to a number of events, including activation of transcription factor NF-κB and programmed cell death (apoptosis). Previous studies of TNF-α signaling have suggested that these two events occur independently. The sensitivity and kinetics of TNF-α-in...

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