Stimulation of Neurogenesis and Synaptogenesis by Bilobalide and Quercetin via Common Final Pathway in Hippocampal Neurons

Tchantchou, Flaubert; N. Lacor, Pascale; Cao, Zhiming; Lao, Lixing; Hou, Yan; Cui, Changhai; L. Klein, William; Luo, Yuan

doi:10.3233/jad-2009-1189

Public

Stimulation of Neurogenesis and Synaptogenesis by Bilobalide and Quercetin via Common Final Pathway in Hippocampal Neurons

Published in Journal of Alzheimer s Disease • Nov 12, 2009

Authors:

Flaubert Tchantchou

Pascale N. Lacor

Zhiming Cao

Abstract

Loss of synapses has been correlated with dementia in Alzheimer's disease (AD) as an early event during the disease progression. Hence, synaptogenesis and neurogenesis in adulthood could serve as a therapeutic target for the prevention and treatment of AD. Recently, we have demonstrated enhanced hip...

Subject

Synaptogenesis

Neurogenesis

CREB

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