Proteolytic processing of Alzheimer’s β‐amyloid precursor protein

J. Neurochem. (2012) 120 (Suppl. 1), 9–21. Abstract β‐Amyloid precursor protein (APP) is a critical factor in the pathogenesis of Alzheimer’s disease (AD). APP undergoes post‐translational proteolysis/processing to generate the hydrophobic β‐amyloid (Aβ) peptides. Deposition of Aβ in the brain, form... View More