<i>N</i>‐Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury

Demougeot, Céline; Garnier, Philippe; Mossiat, Claude; Bertrand, Nathalie; Giroud, Maurice; Beley, A.; Marie, Christine

doi:10.1046/j.1471-4159.2001.00285.x

Public

N‐Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury

Published in Journal of Neurochemistry • Apr 15, 2001

Authors:

Céline Demougeot

Philippe Garnier

Claude Mossiat

Abstract

To evaluate the contribution of cellular dysfunction and neuronal loss to brain N-acetylaspartate (NAA) depletion, NAA was measured in brain tissue by HPLC and UV detection in rats subjected to cerebral injury, associated or not with cell death. When lesion was induced by intracarotid injection of m...

Subject

Penumbra

Lesion

Medicine

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