Resistance to fipronil in Drosophila simulans: influence of two point mutations in the RDL GABA receptor subunit

Le Goff, Gaëlle; Hamon, Alain; Bergé, Jean‐Baptiste; Amichot, Marcel

doi:10.1111/j.1471-4159.2004.02922.x

Public

Resistance to fipronil in Drosophila simulans: influence of two point mutations in the RDL GABA receptor subunit

Published in Journal of Neurochemistry • Feb 17, 2005

Authors:

Gaëlle Le Goff

Alain Hamon

Jean‐Baptiste Bergé

Abstract

The Eyguieres 42 strain of Drosophila simulans, obtained by laboratory selection, displayed approximately 20,000-fold resistance to the insecticide fipronil. Molecular cloning of the cDNA encoding the RDL GABA receptor subunit of this strain revealed the presence of two mutations: the Rdl mutation (...

Subject

Fipronil

Picrotoxin

Biology

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