Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL.

B, He; A, Chadburn; E, Jou; EJ, Schattner; DM, Knowles; A, Cerutti

doi:10.4049/jimmunol.172.5.3268

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Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL.

Shared by NobleBlocks on Mar 1, 2004 • 12:00 AM UTC

Authors:

He B

Chadburn A

Jou E

Abstract

The mechanisms underlying the autonomous accumulation of malignant B cells remain elusive. We show in this study that non-Hodgkin's lymphoma (NHL) B cells express B cell-activating factor of the TNF family (BAFF) and a proliferation-inducing ligand (APRIL), two powerful B cell-activating molecules u...

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