Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes

Bauer, Stefan; C. Jendro, M.; Wadle, Andreas; Kleber, Sascha; Stenner, Frank; Dinser, Robert; Reich, Anja; Faccin, Erica; Gödde, Stefan; Dinges, H.; Müller‐Ladner, Ulf; Renner, Christoph

doi:10.1186/ar2080

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Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes

Published in Arthritis Research & Therapy • Nov 14, 2006

Authors:

Stefan Bauer

M. C. Jendro

Andreas Wadle

Abstract

Fibroblast activation protein (FAP), as described so far, is a type II cell surface serine protease expressed by fibroblastic cells in areas of active tissue remodelling such as tumour stroma or healing wounds. We investigated the expression of FAP by fibroblast-like synoviocytes (FLSs) and compared...

Subject

Myofibroblast

Rheumatology

Medicine

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