Activation of human neutrophils with 1-<i>O</i>-hexadecyl/octadecyl-2-acetyl-<i>sn</i>-glycerol-3-phosphorylcholine (platelet activating factor).

O. Shaw, James; Neal Pinckard, R.; S Ferrigni, K; M. McManus, Linda; J Hanahan, D

doi:10.4049/jimmunol.127.3.1250

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Activation of human neutrophils with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycerol-3-phosphorylcholine (platelet activating factor).

Shared by NobleBlocks on Sep 1, 1981 • 12:00 AM UTC

Authors:

James O. Shaw

R. Neal Pinckard

K S Ferrigni

Abstract

1-O-Hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (AGEPC), the acetylated alkyl phosphoglyceride known as platelet-activating factor, stimulated human neutrophil (PMN) exocytosis, migration, superoxide production and aggregation over a concentration range of 10(-10) to 10(-5) M. AGEPC...

Subject

Platelet-activating factor

Cytochalasin B

Exocytosis

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