Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain.

J. Giudice, George; Emery, Derek; D. Zelickson, Brian; J. Anhalt, Grant; Liu, Zhi; A. Díaz, Luis

doi:10.4049/jimmunol.151.10.5742

Public

Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain.

Shared by NobleBlocks on Nov 1, 1993 • 12:00 AM UTC

Authors:

George J. Giudice

Derek Emery

Brian D. Zelickson

Abstract

Bullous pemphigoid (BP) and herpes gestationis (HG) are skin diseases characterized by subepidermal blisters and autoantibodies against two hemidesmosomal Ag, i.e., BP230 and BP180. Based on sequence analysis the BP180 Ag was predicted to be a transmembrane protein with a long extracellular collagen...

Subject

Ectodomain

Bullous pemphigoid

Autoantibody

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