Impact of pH modifiers and drug exposure on the solubility of pharmaceutical products commonly administered through water delivery systems

M. Dorr, Paul; Madson, Darin; Wayne, Spencer; B. Scheidt, A.; W. Almond, Glen

doi:10.54846/jshap/595

Public

Impact of pH modifiers and drug exposure on the solubility of pharmaceutical products commonly administered through water delivery systems

Shared by NobleBlocks on Jul 1, 2009 • 12:00 AM UTC

Authors:

Paul M. Dorr

Darin Madson

Spencer Wayne

Abstract

Fifteen antimicrobial powders and aspirin were prepared according to label directions and evaluated for pH and temperature, settling after 5 days, and physical-chemical reactions when pairs of products were mixed. Many products changed state or precipitated when mixed with other products or when the...

Subject

Solubility

Drug

Drug delivery

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