Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes

Patel, Anushka; MacMahon, Stephen; Chalmers, John; Neal, Bruce; Billot, Laurent; Woodward, Mark; Marre, Michel; E. Cooper, Mark; Glasziou, Paul; E. Grobbee, Diederick; Hamet, Pavel; Harrap, Stephen; Heller, Simon; Liu, Lisheng; Mancia, Giuseppe; E. Mogensen, C.; Pan, Changyu; R Poulter, Neil; Rodgers, Anthony; Williams, Bryan; Bompoint, Séverine; E. de Galan, Bastiaan; Joshi, Rohina; Travert, F.

doi:10.1056/nejmoa0802987

Public

Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes

Published in New England Journal of Medicine • Jun 6, 2008

Authors:

Anushka Patel

Stephen MacMahon

John Chalmers

Abstract

BACKGROUND: In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain. METHODS: We randomly assigned 11,140 patients with type 2 diabetes to undergo either standard glucose control or intensive glucose control, defined as the use of gliclazide (...

Subject

Medicine

Hazard ratio

Glycated hemoglobin

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