Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869.

Belle S, Van; MR, Lichinitser; RM, Navari; AM, Garin; ML, Decramer; A, Riviere; M, Thant; E, Brestan; B, Bui; K, Eldridge; Smet M, De; N, Michiels; RR, Reinhardt; AD, Carides; JK, Evans; BJ, Gertz

doi:10.1002/cncr.10516

Public

Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869.

Shared by NobleBlocks on Jun 1, 2002 • 12:00 AM UTC

Authors:

Van Belle S

Lichinitser MR

Navari RM

Abstract

Background Recent studies have suggested that antiemetic therapy with a triple combination of the neurokinin-1 receptor antagonist MK-869, a serotonin (5-HT(3)) antagonist, and dexamethasone provides enhanced control of cisplatin-induced emesis compared with standard therapy regimens. The authors co...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!