Bisphosphonates and other bone agents for breast cancer

O’Carrigan, Brent; H. Wong, Matthew; L Willson, Melina; R. Stockler, Martin; Pavlakis, Nick; Goodwin, Annabel

doi:10.1002/14651858.cd003474.pub4

Public

Bisphosphonates and other bone agents for breast cancer

Published in Cochrane Database of Systematic Reviews • Oct 30, 2017

Authors:

Brent O’Carrigan

Matthew H. Wong

Melina L Willson

Abstract

BACKGROUND: Bone is the most common site of metastatic disease associated with breast cancer (BC). Bisphosphonates inhibit osteoclast-mediated bone resorption, and novel targeted therapies such as denosumab inhibit other key bone metabolism pathways. We have studied these agents in both early breast...

Subject

Denosumab

Medicine

Bisphosphonate

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