HLA Class I Depleted hESC as a Source of Hypoimmunogenic Cells for Tissue Engineering Applications

Karabekian, Zaruhi; Ding, Hao; Stybayeva, Gulnaz; Ivanova, Irina; Muselimyan, Narine; Haque, Amranul; Toma, Ian; Gillum Posnack, Nikki; Revzin, Alexander; Leitenberg, David; A. Laflamme, Michael; Sarvazyan, Narine

doi:10.1089/ten.tea.2015.0105

Public

HLA Class I Depleted hESC as a Source of Hypoimmunogenic Cells for Tissue Engineering Applications

Published in Tissue Engineering Part A • Jul 28, 2015

Authors:

Zaruhi Karabekian

Hao Ding

Gulnaz Stybayeva

Abstract

BACKGROUND: Rapidly improving protocols for the derivation of autologous cells from stem cell sources is a welcome development. However, there are many circumstances when off-the-shelf universally immunocompatible cells may be needed. Embryonic stem cells (ESCs) provide a unique opportunity to modif...

Subject

Embryonic stem cell

Flow cytometry

Homeobox protein NANOG

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