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The Regulation of Rabbit Skeletal Muscle Contraction

Published in Journal of Biological Chemistry • Aug 1, 1971
Authors:
James A. Spudich
,
Susan Watt

Abstract

Actin purified by a new, simple, and rapid purification procedure activated the ATPase activity of both heavy meromyosin and Subfragment 1 of heavy meromyosin, and this activation was not inhibited by the removal of Ca2+. Preparations of tropomyosin-troponin inhibited (by 85%) both the acto-heavy me...

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