IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells.

Okada, Masaji; Kitahara, Masanori; Kishimoto, S.; Matsuda, Tadashi; Hirano, Takao; Kishimoto, Tadamitsu

doi:10.4049/jimmunol.141.5.1543

Public

IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells.

Published in The Journal of Immunology • Sep 1, 1988

Authors:

Masaji Okada

Masanori Kitahara

S. Kishimoto

Abstract

rIL-6/B cell stimulatory factor 2 was found to augment CTL generation from mature as well as immature human T cells stimulated with UV-treated allogeneic cells. rIL-6 also acted on peanut agglutinin-positive murine thymocytes and Lyt-2-positive splenic T cells to give rise to CTL. rIL-6 alone could ...

Subject

CTL*

Cytotoxic T cell

In vitro

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