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Control of synaptic strength by glial TNFalpha.

Published in Science (New York, N.Y.) • Mar 22, 2002
Authors:
Eric C Beattie
,
David Stellwagen
,
Wade Morishita

Abstract

Activity-dependent modulation of synaptic efficacy in the brain contributes to neural circuit development and experience-dependent plasticity. Although glia are affected by activity and ensheathe synapses, their influence on synaptic strength has largely been ignored. Here, we show that a protein pr...

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