Ceroid Histiocytosis of Spleen and Bone Marrow in Idiopathic Thrombocytopenic Purpura (ITP): A Contribution to the Understanding of the Sea-blue Histiocyte

M. Rywlin, Arkadi; A. HERNANDEZ, JUAN; E. Chastain, Doyle; Pardo, Victoriano

doi:10.1182/blood.v37.5.587.587

Public

Ceroid Histiocytosis of Spleen and Bone Marrow in Idiopathic Thrombocytopenic Purpura (ITP): A Contribution to the Understanding of the Sea-blue Histiocyte

Published in Blood • May 1, 1971

Authors:

Arkadi M. Rywlin

JUAN A. HERNANDEZ

Doyle E. Chastain

Abstract

Abstract Ceroid-containing histiocytes are described for the first time in the spleen and marrow of a patient with ITP. Ceroid results from the oxidation and polymerization of unsaturated lipids and may appear in histiocytes in a variety of diseases. With the Wright or Giemsa methods, ceroid granule...

Subject

Histiocyte

Lipofuscin

Pathology

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