Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

Kikkawa, Ushio; Takai, Yoshimi; Minakuchi, R; Inohara, Shinichi; Nishizuka, Yasutomi

doi:10.1016/s0021-9258(18)33453-7

Public

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

Published in Journal of Biological Chemistry • Nov 1, 1982

Authors:

Ushio Kikkawa

Yoshimi Takai

R Minakuchi

Abstract

in rat brain was investigated.Approximately one-third of the protein kinase was recovered in the soluble cytosol fraction, another one-third was in the crude mitochondrial fraction, and the rest was in nuclear and microsomal fractions.Upon further analysis of the crude mitochondrial fraction, most o...

Subject

Phospholipid

Calcium

Distribution (mathematics)

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