Comparing sequences without using alignments: application to HIV/SIV subtyping

Didier, Gilles; Debomy, Laurent; Pupin, Maude; Zhang, Ming; Grossmann, A.; Devauchelle, Claudine; Laprevotte, Ivan

doi:10.1186/1471-2105-8-1

Public

Comparing sequences without using alignments: application to HIV/SIV subtyping

Published in BMC Bioinformatics • Jan 2, 2007

Authors:

Gilles Didier

Laurent Debomy

Maude Pupin

Abstract

BACKGROUND: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for instance ambiguous regions) are deleted before tree building. To overcome this difficulty, one of us previously introduced a ...

Subject

Subtyping

Human immunodeficiency virus (HIV)

Computer science

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