Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes

Romero, Pedro; Zippelius, Alfred; Kurth, Isabel; J Pittet, Mikaël; Touvrey, Cédric; M Iancu, Emanuela; Corthesy, Patricia; Devevre, Estelle; E Speiser, Daniel; Rufer, Nathalie

doi:10.4049/jimmunol.178.7.4112

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Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes

Shared by NobleBlocks on Apr 1, 2007 • 12:00 AM UTC

Authors:

Pedro Romero

Alfred Zippelius

Isabel Kurth

Abstract

Abstract In humans, the pathways of memory and effector T cell differentiation remain poorly defined. We have dissected the functional properties of ex vivo effector-memory (EM) CD45RA−CCR7− T lymphocytes present within the circulating CD8+ T cell pool of healthy individuals. Our studies show that E...

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