Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine

C.Y. Chang, Catherine; Sakashita, Naomi; Ørnvold, Kim; Lee, Oneil; T. Chang, Ellen; Dong, Ruhong; Lin, Song; Gregory Lee, Chi‐Yu; C. Strom, Stephen; Kashyap, Randeep; J. Fung, John; V. Farese, Robert; Patoiseau, Jean‐François; Delhon, André; Chang, Ta‐Yuan

doi:10.1074/jbc.m003927200

Public

Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine

Published in Journal of Biological Chemistry • Sep 1, 2000

Authors:

Catherine C.Y. Chang

Naomi Sakashita

Kim Ørnvold

Abstract

By using specific anti-ACAT-1 antibodies in immunodepletion studies, we previously found that ACAT-1, a 50-kDa protein, plays a major catalytic role in the adult human liver, adrenal glands, macrophages, and kidneys but not in the intestine. Acyl-coenzyme A:cholesterol acyltransferase (ACAT) activit...

Subject

Small intestine

Chemistry

Internal medicine

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