Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure

Lai, Dongmei; Wang, Fangyuan; Yao, Xiaofen; Zhang, Qiuwan; Wu, Xiaoxing; Xiang, Charlie

doi:10.1186/s12967-015-0516-y

Public

Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure

Published in Journal of Translational Medicine • May 11, 2015

Authors:

Dongmei Lai

Fangyuan Wang

Xiaofen Yao

Abstract

BACKGROUND: Human endometrial mesenchymal stem cells (EnSCs) derived from menstrual blood have mesenchymal stem/stromal cells (MSCs) characteristics and can differentiate into cell types that arise from all three germ layers. We hypothesized that EnSCs may offer promise for restoration of ovarian dy...

Subject

Germline

Mesenchymal stem cell

Stem cell

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