Thromboembolic Events After Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-Controlled Studies

J. Milling, Truman; A. Refaai, Majed; N. Goldstein, Joshua; Schneider, Astrid; Omert, Laurel; Harman, Amy; L. Lee, Martin; Sarode, Ravi

doi:10.1016/j.annemergmed.2015.04.036

Public

Thromboembolic Events After Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-Controlled Studies

Published in Annals of Emergency Medicine • Jun 18, 2015

Authors:

Truman J. Milling

Majed A. Refaai

Joshua N. Goldstein

Abstract

STUDY OBJECTIVE: We evaluated thromboembolic events after vitamin K antagonist reversal in post hoc analyses of pooled data from 2 randomized trials comparing 4-factor prothrombin complex concentrate (4F-PCC) (Beriplex/Kcentra) with plasma. METHODS: Unblinded investigators identified thromboembolic ...

Subject

Medicine

Prothrombin complex concentrate

Vitamin K antagonist

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