Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5’-regulatory region. Induction by cytokines and phorbol ester

Voraberger, Günter; Schäfer, Reinhold; Stratowa, Christian

doi:10.4049/jimmunol.147.8.2777

Public

Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5’-regulatory region. Induction by cytokines and phorbol ester

Published in The Journal of Immunology • Oct 1, 1991

Authors:

Günter Voraberger

Reinhold Schäfer

Christian Stratowa

Abstract

Human intercellular adhesion molecule-1 (ICAM-1), a specific ligand for the lymphocyte function-associated Ag-1 (LFA-1), plays an important role in leukocyte-endothelial cell interactions. It is induced by proinflammatory cytokines such as IL-1, TNF-alpha, or IFN-gamma. However, little is known conc...

Subject

Biology

Molecular biology

Intron

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