B7-H3 participates in the development of experimental pneumococcal meningitis by augmentation of the inflammatory response via a TLR2-dependent mechanism.

X, Chen; EM, Quinn; H, Ni; J, Wang; S, Blankson; HP, Redmond; JH, Wang; X, Feng

doi:10.4049/jimmunol.1103715

Public

B7-H3 participates in the development of experimental pneumococcal meningitis by augmentation of the inflammatory response via a TLR2-dependent mechanism.

Shared by NobleBlocks on Jun 1, 2012 • 12:00 AM UTC

Authors:

Chen X

Quinn EM

Ni H

Abstract

In addition to a well-documented role in regulating T cell-mediated immune responses, B7-H3, a newly discovered member of the B7 superfamily, has been recently identified as a costimulator in the innate immunity-mediated inflammatory response. In this study, we further report that B7-H3 participates...

Discussions