The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

J. Clark, Barbara; A Wells, J; R King, S; M. Stocco, D.

doi:10.1016/s0021-9258(18)46930-x

Public

The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

Published in Journal of Biological Chemistry • Nov 1, 1994

Authors:

Barbara J. Clark

J A Wells

S R King

Abstract

The acute response of steroidogenic cells to trophic hormone stimulation is the mobilization of cholesterol from cellular stores to the mitochondrial outer membrane and the transfer of this cholesterol to the mitochondrial inner membrane where the first enzymatic step in steroidogenesis occurs. The ...

Subject

Steroidogenic acute regulatory protein

Cloning (programming)

Luteinizing hormone

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