IL-17A Produced by γδ T Cells Plays a Critical Role in Innate Immunity against <i>Listeria monocytogenes</i> Infection in the Liver

Hamada, Satoru; Umemura, Masayuki; Shiono, Takeru; Tanaka, Kensho; Yahagi, Ayano; Dilara Begum, Mst.; Oshiro, Kiyotetsu; Okamoto, Yuko; Watanabe, Hisami; Kawakami, Kazuyoshi; L. Roark, Christina; K. Born, Willi; L. O’Brien, Rebecca; Ikuta, Koichi; Ishikawa, Hiromichi; Nakae, Susumu; Iwakura, Yoichiro; Ohta, Takao; Matsuzaki, Goro

doi:10.4049/jimmunol.181.5.3456

Public

IL-17A Produced by γδ T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver

Published in The Journal of Immunology • Sep 1, 2008

Authors:

Satoru Hamada

Masayuki Umemura

Takeru Shiono

Abstract

IL-17A is originally identified as a proinflammatory cytokine that induces neutrophils. Although IL-17A production by CD4(+) Th17 T cells is well documented, it is not clear whether IL-17A is produced and participates in the innate immune response against infections. In the present report, we demons...

Subject

Listeria monocytogenes

Innate immune system

Immunity

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!