Amyloid β Protein (Aβ) in Alzheimeri's Disease Brain

A. Gravina, Stephen; Ho, Libin; B. Eckman, Christopher; E. Long, Kristin; Ötvös, László; H. Younkin, Linda; Suzuki, Nobuhiro; G. Younkin, Steven

doi:10.1074/jbc.270.13.7013

Public

Amyloid β Protein (Aβ) in Alzheimeri's Disease Brain

Published in Journal of Biological Chemistry • Mar 1, 1995

Authors:

Stephen A. Gravina

Libin Ho

Christopher B. Eckman

Abstract

Biochemical and immunocytochemical analyses were performed to evaluate the composition of the amyloid beta protein (A beta) deposited in the brains of patients with Alzheimer's disease (AD). To quantitate all A beta s present, cerebral cortex was homogenized in 70% formic acid, and the supernatant w...

Subject

Angiopathy

Senile plaques

Pathology

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